2016 Fiscal Year Final Research Report
The establishment of nutrition therapy and the pathophysiological assessment for cardiac cachexia and aspiration pneumonia with targeting sarcopenia.
| Project/Area Number |
26461068
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cardiovascular medicine
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| Research Institution | Shiga University of Medical Science |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 心不全 / 栄養障害 |
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| Outline of Final Research Achievements |
We evaluated the nutritional status of patients with chronic heart failure (CHF) by body composition analysis and indirect calorimetry. 34 patients with chronic heart failure and 19 control subjects were recruited in this study. In results, the patients with severe CHF have malnutrition characterized by the reduction of body fat and skeletal muscle mass of lower limbs compared to control subjects. Furthermore, in patients with severe CHF, the energy consumption tends to exceed the energy intake, resulting in the negative energy balance. The reason of the negative energy balance in patients with CHF is due to both the reduction of energy intake and the acceleration of the energy consumption. The negative energy balance is likely to be deteriorated as the severity of CHF is worsened.
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| Free Research Field |
医歯薬学
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