Cross-talk between uppper and lower airway involvenet assesed by CT imaging and biomarkers in asthmatic subjects

2016 Fiscal Year Final Research Report

• Project/Area Number: 26461151
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Respiratory organ internal medicine
• Research Institution: Hokkaido University
• Principal Investigator: Konno Satoshi 北海道大学, 医学研究科, 准教授 (20399835)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 気管支喘息

Outline of Final Research Achievements

This study was aimed aim to evaluate the effect of smoking on the relationship
between sinus involvement and asthma-related indices. Resuts from this study showed that sinusitis and asthma are expressions of a common process characterized by intense Th2-related inflammation,regardless of smoking status. However, such Th2-related inflammation may be linked withfixed airflow limitation only in non-smoking asthmatics.

Free Research Field

呼吸器内科学