High resolution DWI to valuate diasese in the skull and head and neck

2016 Fiscal Year Final Research Report

• Project/Area Number: 26461826
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kyushu University
• Principal Investigator: Hiwatahi Akio 九州大学, 大学病院, 助教 (30444855)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 拡散強調像 / MRI / 下垂体腺腫

Outline of Final Research Achievements

This retrospective study included 23 adult patients with pituitary adenomas. Among them, 6 each
were prolactin-producing adenomas and growth hormone producing adenomas (GH) and the remaining 11 were non-functioning adenomas (NON). The apparent diffusion coefficients (ADCs) were measured in the pituitary adenoma and in the unaffected pituitary gland using coronal reformatted plane. All pituitary adenomas were clearly visualized on DSDE-TFE and ADC maps without obvious geometrical distortion. There were no statistically significant differences in ADC of the all pituitary adenoma (1.50±0.61×10-3mm2/s) and the unaffected anterior lobe of the pituitary gland (1.49 ±0.3×10-3mm2/s,p=0.99). The ADC in prolactin-producing adenomas (2.04±0.76×10-3mm2/s) was significantly higher than that in GH (1.26±0.47×10-3mm2/s, p<0.05) and NON (1.33±0.42×10-3mm2/s, p=0.04). There was no statistically
significant difference between GH and NON (p50.97).

Free Research Field

神経放射線学