2016 Fiscal Year Final Research Report
Gene mutation analysis of esophageal cancer in the era of post genome-sequense
| Project/Area Number |
26461986
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | Nagoya City University |
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Principal Investigator |
KIMURA Masahiro 名古屋市立大学, 大学院医学研究科, 研究員 (50336682)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 次世代シークエンス / 食道癌 |
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| Outline of Final Research Achievements |
Next generataion Sequence was done about 400 genes using Truseq Custum Trial kit (Cancer Gene) for 48 samples of esophageal cancer. We found the mutaion of 7 genes involved T factor (AKAP9, ATM, CYTSB, DDX10, MYH7, MYST4 and PRDM16) Moreover, we found 8 gene mutaion involved N factor (BCR, CARD11, FANCA, JAZF1, NIN, NSD1, RAMBP17 and REQL4).
This result of analysis for these 400 genes were similar to 30,000 genes of whole genomic analysis in other facilities.
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| Free Research Field |
医歯薬学
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