2016 Fiscal Year Final Research Report
Does the intake of n-3 fatty acids contribute to infant growth and development -Verification by epidemiology-
| Project/Area Number |
26500016
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Integrated Nutrition Science
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| Research Institution | Kagawa Nutrition University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | n-3系脂肪酸 / 出生コホート / 母乳 / 血液 / 脂肪酸不飽和化酵素 / スニップ / トランス脂肪酸 |
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| Outline of Final Research Achievements |
We examined the relationship between mothers’ fish intakes and n-3 fatty acid metabolism during the lactation period and the growth and development of their infants. The compositions and concentrations of the n-3 fatty acid docosahexaenoic acid (DHA) in maternal milk were significantly positively correlated with the mothers’ fish intakes. The C/C type of the rs174547 SNP in the delta-5 fatty acid desaturase gene was found in 15% of mothers, the DHA composition (wt%) of maternal milk of mothers with the C/C type was significantly lower than that of mothers with the T/T type. When the growth of infants was analyzed according to the DHA concentration ingested from birth to 7 months, no association was found between DHA concentration and the weight gain of infants. We believe that further analysis is required to clarify the relationship between DHA ingestion and growth in infants.
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| Free Research Field |
脂質栄養学
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