Analysis of mouse behavior under different gravity conditions

2016 Fiscal Year Final Research Report

• Project/Area Number: 26506031
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: 宇宙生命学
• Research Institution: Japan Aerospace EXploration Agency
• Principal Investigator: Shiba Dai 国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 主任研究開発員 (50360722)
• Co-Investigator(Renkei-kenkyūsha): MORITA hironobu 岐阜大学, 医学研究科, 教授 (80145044) ; SUGIYAMA noriyuki 大阪医科大学, 医学部, 講師 (90381954)
• Research Collaborator: SHIMOMURA michihiko 国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 主任研究開発員
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 重力 / 前庭機能 / 平衡機能 / 行動解析 / センサー

Outline of Final Research Achievements

Animals have a function to sense acceleration changes in the inner ear, but it is not clear at the molecular level about how much changes can be detected and how to sense the subtle changes. In addition, while animals have a system to sense changes, they can adapt to a new environment if the change is in a permanent state. In other words, the sensing system is sensitive and flexible.
In this study, in order to analyze the activity under the hyper gravity environment, the cage with video camera, which can be housed individually, was placed in a centrifuge and the mice were reared for 2 weeks. In addition, we developed a "pixel analysis system" that analyzes the activity from mouse behavior, and evaluated the time when the mice were mostly affected by hyper gravity.

Free Research Field

重力生物学