2015 Fiscal Year Final Research Report
An attempt to identify circulating exosomal miRNA biomarkers for assessment of carcass traits and meat quality characteristics of Japanese Black cattle
| Project/Area Number |
26660215
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Animal production science
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| Research Institution | Kinki University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAGAI Kouhei 近畿大学, 生物理工学部, 講師 (70500578)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | バイオマーカー |
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| Outline of Final Research Achievements |
In this study, to identify circulating exosomal miRNA biomarkers for predicting carcass traits and meat quality characteristics of Japanese Black cattle by bioinformatics analysis, we first compared exosomal miRNA expression profiles of serum between low and high merit steers in main carcass traits. We then inferred the involvement of the lower- or higher-expressed exosomal miRNAs in metabolic pathways by computational searches of existing public databases (miRDB, and PANTHER). As a result, our study suggests the possibility of at least eight identified exosomal miRNAs as biomarker candidates for predicting carcass traits and meat quality characteristics during fattening of Japanese Black cattle.
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| Free Research Field |
バイオインフォマティクス
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