Development of epigenetic reporter mice and their application in development and dedifferentiation process studies.

2015 Fiscal Year Final Research Report

• Project/Area Number: 26870343
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Molecular biology; Developmental biology
• Research Institution: Chubu University
• Principal Investigator: UEDA Jun 中部大学, 実験動物教育研究センター, 助教 (80450394)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Keywords: エピジェネティクス / ライブセルイメージング / DNAのメチル化

Outline of Final Research Achievements

Recent studies have indicated that epigenetics change dynamically not only during developmental and differentiation processes, but also in pathological processes, including tumorigenesis. To analyze and track the epigenetic dynamics during development, differentiation and tumorigenic processes, we have generated epigenetic reporter mice and utilized them to study these processes.

Free Research Field

発生生物学