KAKEN — Research Projects | Researcher Number: 70090488

Search Results: 8 results / Researcher Number: 70090488

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1. Endocrinological and Immunological Roles of Toll-like Receptor 3 in Culture Human Thyroid Follicles

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Endocrinology
Research Institution	Tokyo Women's Medical University
Principal Investigator	SATO Kanji Tokyo Women's Medical University, Graduate School of Medicine, Professor
Project Period (FY)	2005 – 2006Completed
Keywords	Toll-like receptor-3 / double-stranded RNA / type I interferon / thyroid follicles / subacute thyroiditis / vascular endothelial growth factor / thyroidal blood flow / inorganic iodide
Research Abstract	Recently, it was shown that pathogen-associated molecular patterns (PAMPS) stimulate Toll-like receptors (TLR) and activate innate immune responses by ...

Research Products of this project	Journal Article (10 results) Book (2 results)

2. GENES REGULATED BY PHOSPHATE-INDUCED PARATHYROID CELL PROLIFERATION IN ORGAN CULTURE : ANALYSIS USING OLIGO-DNA MICROARRAY

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Endocrinology
Research Institution	Tokyo Women's Medical University
Principal Investigator	SATO Kanji Tokyo Women's Medical University, Associate Professor
Project Period (FY)	2003 – 2004Completed
Keywords	parathyroid gland / cDNA microarray / phosphate / PTH / growth factors / prion
Research Abstract	A patient with hypophosphatemic osteomalacia, who was treated with high phosphate, developed tertiary hyperparathyroidism. Gene analysis of the four h ...

Research Products of this project	Journal Article (15 results) Publications (2 results)

3. The volumetric methods in the lesions for radioisotope therapy

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Radiation science
Research Institution	Tokyo Women's Medical University
Principal Investigator	KUSAKABE Kiyoko Tokyo Women's Medical University, Medical Department, Professor
Project Period (FY)	1999 – 2000Completed
Keywords	Dosimetry / Radioisotope therapy / Functioning mass volume / Grave's disease / Thyroid cancer
Research Abstract	The estimation of functioning volume in the lesion is an important factor to know the severity of illness. We had been tried to develop the easy metho ...

Research Products of this project	Publications (10 results)

4. Vascular endothelial growth factor-C mRNA expression on lymphatic metastasis of thyroid papillary carcinoma

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	General surgery
Research Institution	Tokyo Women's Medical University
Principal Investigator	OBARA Takao Tokyo Women's Medical University, School of Medicine, Professor
Project Period (FY)	1998 – 1999Completed
Keywords	vascular endothelial growth factor / papillary thyroid carcinoma / follicular thyroid carcinoma / metastasis
Research Abstract	Background : ...

Research Products of this project	Publications (3 results)

5. 原発性副甲状腺機能亢進症患者のビタミンD受容体遺伝子多型と骨密度および手術適応

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	General surgery
Research Institution	Tokyo Women's Medical University
Principal Investigator	小原孝男東京女子医科大学, 医学部, 教授
Project Period (FY)	1996Completed
Keywords	原発性副甲状腺機能亢進症 / ビタミンD受容体遺伝子多型 / 骨密度
Research Abstract	〈目的〉骨密度は、ビタミンD受容体遺伝子多型により影響を受けていることが報告された。原発性副甲状腺機能亢進症(Primary hyperparathyroidism,PHP)患者のビタミンD受容体遺伝子多型と骨密度ならびに各種骨代謝マーカーとの関連性を検討し、ビタミンD受容体遺伝子多型がPHP患者の ...

6. 甲状腺乳頭癌における接着分子および裏うち蛋白の発現異常と生物学的悪性度の関連

Research Project

Research Category	Grant-in-Aid for General Scientific Research (C)
Research Field	General surgery
Research Institution	Tokyo Women's Medical University
Principal Investigator	山下共行東京女子医科大学, 医学部, 講師
Project Period (FY)	1995 – 1996Completed
Keywords	甲状腺乳頭癌 / 接着分子 / E-カドヘリン / 病理組織学
Research Abstract	近年癌の浸潤、転移に癌細胞の接着性の喪失が深く関与していることが明らかとなってきた。本研究は、甲状腺乳頭癌において細胞接着性の喪失と病理組織所見、予後との関連があるかを細胞接着分子の発現の点から解明することを目的としている。

Research Products of this project	Publications (2 results)

7. Flow-cytometric DNA analysis for pathological diagnosis of parathyroid carcinoma.

Research Project

Research Category	Grant-in-Aid for General Scientific Research (C)
Research Field	General surgery
Research Institution	Tokyo Women's Medical College
Principal Investigator	OBARA Takao Tokyo Women's Medical College, Department of Endocrine Surgery
Project Period (FY)	1987 – 1988Completed
Keywords	Primary hyperparathyroidism / Parathyroid carcinoma / Parathyroid adenoma / Primary hyperplasia / Flowcytometry
Research Abstract	Flow cytometric DNA analysis was performed on 68 paraffin-embedded parathyroid tumors from 49 patients with primary hyperparathyroidism (15 cancers-13 ...

Research Products of this project	Publications (15 results)

8. Parathyroid carcinoma:Criteria for the diagnosis and appropriate therapy of recurrence.

Research Project

Research Category	Grant-in-Aid for General Scientific Research (C)
Research Field	General surgery
Research Institution	Tokyo Women's Medical College
Principal Investigator	OBARA Takao Tokyo Women's Medical College, Department of Endocrine Surgery
Project Period (FY)	1985 – 1986Completed
Keywords	Parathyroid carcinoma / Primary hyperparathyroidism / Hypercalcemia / Flowcytometric DNA analysis / Localization study for recurrent parathyroid carcinoma
Research Abstract	In an attempt to assess the reliability of pathological criteria for the diagnosis of parathyroid carcinoma, this work underwent (1)long term follow-u ...

Research Products of this project	Publications (8 results)