Neural information dynamics in the cerebral cortex and subcortical regions in human decision-making

• Project Area: Brain information dynamics underlying multi-area interconnectivity and parallel processing
• Project/Area Number: 17H06314
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Complex systems
• Research Institution: National Institute of Information and Communications Technology
• Principal Investigator: Haruno Masahiko 国立研究開発法人情報通信研究機構, 未来ICT研究所脳情報通信融合研究センター, 室長 (40395124)
• Co-Investigator(Kenkyū-buntansha): 吉田 和子 株式会社国際電気通信基礎技術研究所, 脳情報通信総合研究所, 客員研究員 (30379599) ; 田村 弘 大阪大学, 大学院生命機能研究科, 准教授 (80304038)
• Project Period (FY): 2017-06-30 – 2022-03-31
• Project Status: Completed (Fiscal Year 2022)
• Budget Amount: ¥124,280,000 (Direct Cost: ¥95,600,000、Indirect Cost: ¥28,680,000); Fiscal Year 2021: ¥25,740,000 (Direct Cost: ¥19,800,000、Indirect Cost: ¥5,940,000); Fiscal Year 2020: ¥25,740,000 (Direct Cost: ¥19,800,000、Indirect Cost: ¥5,940,000); Fiscal Year 2019: ¥25,740,000 (Direct Cost: ¥19,800,000、Indirect Cost: ¥5,940,000); Fiscal Year 2018: ¥25,740,000 (Direct Cost: ¥19,800,000、Indirect Cost: ¥5,940,000); Fiscal Year 2017: ¥21,320,000 (Direct Cost: ¥16,400,000、Indirect Cost: ¥4,920,000)
• Keywords: 脳情報 / 計算理論 / 7テスラfMRI / ダイナミックス / ７テスラfMRI / 7テスラMRI / ダイナミクス

Outline of Final Research Achievements

In many instances of everyday social behavior, it is known that the response time for self-oriented behavior is longer than for pro-social behavior. However, underlying neural mechanism was unaddressed. We found the key component to be the time needed for the pregenual anterior cingulate cortex to suppress the emotional responses of the amygdala to the difference in gain between self and others. This finding was made possible by using the parameters of the Drift Diffusion Model, which explains both behavioral choices and response times.

Academic Significance and Societal Importance of the Research Achievements

日常の社会行動の多くの場合において、向社会行動より向自己行動の方が反応時間が長くなるのは、自己と他者の利得差に対する(主に)扁桃体の情動反応を背測前帯状回皮質が抑制することに時間を要するためであることを示した。この発見は、行動選択と反応時間の両方を説明するDrift Diffusion Modelのパラメータを用いることで初めて可能となった。この結果は第一に、向自己行動は従来考えられてきたほど単純な行動ではなく、ストレスを伴うものあること、第二に、意思決定の神経機構を同定する際に選択された行動とともにその反応時間を考慮することの重要性を示唆する。

Research Products

• [Journal Article] The initial decrease in 7T-BOLD signals detected by hyperalignment contains information to decode facial expressions (2022)
  • Author(s): Tanaka Toshiko、Okamoto Naohiro、Kida Ikuhiro、Haruno Masahiko
  • Journal Title: NeuroImage Volume: 262 Pages: 119537-119537
  • DOI: 10.1016/j.neuroimage.2022.119537
  • Peer Reviewed / Open Access
• [Journal Article] Gender differences in guilt aversion in Korea and the United Kingdom (2022)
  • Author(s): Tsuyoshi Nihonsugi, Toshiko Tanaka and Masahiko Haruno
  • Journal Title: Scientific Reports Volume: 12(1) Issue: 1
  • DOI: 10.1038/s41598-022-12163-y
  • Peer Reviewed / Open Access
• [Journal Article] Natural Language Content Mediates the Association Between Active Interactions on Social Network Services and Subjective Well-Being (2022)
  • Author(s): Mori Kazuma、Hadjur Hugo、Haruno Masahiko
  • Journal Title: Cyberpsychology, Behavior, and Social Networking Volume: 25 Issue: 10 Pages: 678-685
  • DOI: 10.1089/cyber.2021.0340
  • Peer Reviewed / Open Access
• [Journal Article] Resting functional connectivity of the left inferior frontal gyrus with the dorsomedial prefrontal cortex and temporoparietal junction reflects the social network size for active interactions (2022)
  • Author(s): Mori Kazuma、Haruno Masahiko
  • Journal Title: Human Brain Mapping Volume: 43 Issue: 9 Pages: 2869-2879
  • DOI: 10.1002/hbm.25822
  • Peer Reviewed / Open Access
• [Journal Article] Functional Connectivity Basis and Underlying Cognitive Mechanisms for Gender Differences in Guilt Aversion (2021)
  • Author(s): Nihonsugi Tsuyoshi、Numano Shotaro、Haruno Masahiko
  • Journal Title: eNeuro Volume: 8 Issue: 6 Pages: ENEURO.0226-21.2021
  • DOI: 10.1523/eneuro.0226-21.2021
  • Peer Reviewed / Open Access
• [Journal Article] Dissociable Behavioral and Neural Correlates for Target-Changing and Conforming Behaviors in Interpersonal Aggression (2020)
  • Author(s): Takami K, Haruno M
  • Journal Title: eNeuro Volume: - Issue: 3 Pages: ENEURO.0273-19.2020
  • DOI: 10.1523/eneuro.0273-19.2020
  • Peer Reviewed / Open Access
• [Journal Article] Differential ability of network and natural language information on social media to predict interpersonal and mental health traits Journal of Personality (2020)
  • Author(s): Kazuma Mori, Masahiko Haruno
  • Journal Title: Journal of Personality Volume: - Issue: 2 Pages: 228-243
  • DOI: 10.1111/jopy.12578
  • Peer Reviewed / Open Access
• [Journal Article] Value computations underlying human proposer behavior in the ultimatum game. (2020)
  • Author(s): Pulcu Erdem、Haruno Masahiko
  • Journal Title: Journal of Experimental Psychology: General Volume: 149 Issue: 1 Pages: 125-137
  • DOI: 10.1037/xge0000621
  • Peer Reviewed
• [Journal Article] Computing Social Value Conversion in the Human Brain (2019)
  • Author(s): Fukuda Haruaki、Ma Ning、Suzuki Shinsuke、Harasawa Norihiro、Ueno Kenichi、Gardner Justin L.、Ichinohe Noritaka、Haruno Masahiko、Cheng Kang、Nakahara Hiroyuki
  • Journal Title: The Journal of Neuroscience Volume: 39 Issue: 26 Pages: 5153-5172
  • DOI: 10.1523/jneurosci.3117-18.2019
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Activity in the dorsal ACC causes deterioration of sequential motor performance due to anxiety (2019)
  • Author(s): Ganesh Gowrishankar、Minamoto Takehiro、Haruno Masahiko
  • Journal Title: Nature Communications Volume: 10 Issue: 1 Pages: 4287-4287
  • DOI: 10.1038/s41467-019-12205-6
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Interactive effects of OXTR and GAD1 on envy-associated behaviors and neural responses (2019)
  • Author(s): Tanaka Toshiko、Nishimura Fumichika、Kakiuchi Chihiro、Kasai Kiyoto、Kimura Minoru、Haruno Masahiko
  • Journal Title: PLOS ONE Volume: 14 Issue: 1 Pages: 0210493-0210493
  • DOI: 10.1371/journal.pone.0210493
  • Peer Reviewed / Open Access
• [Journal Article] Behavioral and functional connectivity basis for peer-influenced bystander participation in bullying (2018)
  • Author(s): Takami Kyosuke、Haruno Masahiko
  • Journal Title: Social Cognitive and Affective Neuroscience Volume: 14 Issue: 1 Pages: 23-33
  • DOI: 10.1093/scan/nsy109
  • Peer Reviewed / Open Access
• [Journal Article] Brain response patterns to economic inequity predict present and future depression indices (2017)
  • Author(s): Toshiko Tanaka, Takao Yamamoto, Masahiko Haruno
  • Journal Title: Nature Human Behaivior Volume: 1 Issue: 10 Pages: 748-756
  • DOI: 10.1038/s41562-017-0207-1
  • Peer Reviewed
• [Presentation] Activity in the dorsal ACC causes deterioration of sequential motor performance due to anxiety (2019)
  • Author(s): 春野雅彦
  • Organizer: Events _ Max Planck Institute for Biological Cybernetics Tübing
  • Invited
• [Presentation] Activity in the dorsal ACC causes motor performance deterioration due to anxiety (2018)
  • Author(s): 春野雅彦
  • Organizer: Experimental Psychology Seminar
  • Invited
• [Presentation] Amygdala and dorsolateral prefrontal cortex in human prosocial behavior (2018)
  • Author(s): 春野雅彦
  • Organizer: International symposium on Brain Information Dynamics 2018
  • Int'l Joint Research / Invited
• [Presentation] ヒトの向社会性を実現する大脳皮質と皮質下領域のインタラクション (2017)
  • Author(s): 春野雅彦
  • Organizer: 次世代脳プロジェクト冬のシンポジウム2017
  • Invited
• [Remarks] 脳情報通信融合研究センター
  • URL: https://cinet.jp/japanese/people/2014279/
• [Remarks] Computational Social Neuroscience Group
  • URL: https://cinet-decision-lab.nict.go.jp/
• [Remarks] 脳情報と社会行動研究グループ（春野グループ）
  • URL: http://www2.nict.go.jp/bnc/haruno/website/jp/index.html
• [Patent(Industrial Property Rights)] 脳活動刺激システム、および脳活動刺激装置 (2019)
  • Inventor(s): 春野雅彦
  • Industrial Property Rights Holder: 春野雅彦
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2019-169022
  • Filing Date: 2019