Exploration of Electronic/Ionic Functions of Aquatic Functional Materials

• Project Area: Aquatic Functional Materials: Creation of New Materials Science for Environment-Friendly and Active Functions
• Project/Area Number: 19H05719
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: Kyoto University
• Principal Investigator: 田中 求 京都大学, 高等研究院, 特任教授 (00706814)
• Co-Investigator(Kenkyū-buntansha): 中畑 雅樹 大阪大学, 大学院理学研究科, 助教 (40755641)
• Project Period (FY): 2019-06-28 – 2024-03-31
• Project Status: Completed (Fiscal Year 2023)
• Budget Amount: ¥117,130,000 (Direct Cost: ¥90,100,000、Indirect Cost: ¥27,030,000); Fiscal Year 2023: ¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000); Fiscal Year 2022: ¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000); Fiscal Year 2021: ¥20,670,000 (Direct Cost: ¥15,900,000、Indirect Cost: ¥4,770,000); Fiscal Year 2020: ¥23,400,000 (Direct Cost: ¥18,000,000、Indirect Cost: ¥5,400,000); Fiscal Year 2019: ¥34,840,000 (Direct Cost: ¥26,800,000、Indirect Cost: ¥8,040,000)
• Keywords: 生物着想分子材料 / 半導体電子材料 / 界面制御 / 電子・イオン機能

Outline of Research at the Start

本研究課題は、生物の持つ高感度で選択的な機能を、強靭性・安定性をもつ人工材料で実現することに焦点をあて、水と無機・有機半導体材料の界面接続（つなぐ）により、水圏電子・イオン機能材料を創製するための基礎学理の確立を目指す。
田中求の専門とする半導体材料と生体融合材料による融合電子材料を核に、中畑（研究分担者）の分子認識機能を有する生物着想材料を組み合わせ、水圏の有害イオンを超高効率で捕捉して環境浄化する機能を有する水圏電子・イオン機能材料や、水圏の微小な環境変化を超高感度で検知し電視信号として発信する、機能材料を設計・創製する。

Outline of Annual Research Achievements

本研究課題は、田中求（研究代表者）の専門である界面制御技術と中畑（研究分担者）が得意とする生物着想型高分子材料を融合させて、材料と水圏環境の界面水和構造を制御することで「水圏で作動する電子・イオン機能材料」の創製およびそのための基礎学理の確立を目的としている。令和5年度の研究実施に当たっては、これまでの成果をさらに大きく発展展開すべく、以下のような計画に沿って研究を推進した。
まず、重金属イオンを選択的に捕捉する生物着想材料については、これまでに論文として発表したQCM-Dや周波数変調AFMを用いた界面水和構造変化の精密計測から最適化した、工業廃水モデルをWHOが定める飲料水レベルまで浄化する水圏環境浄化デバイスの作製に成功した（Preprintとして発表済み、現在修正稿が査読中）。また論文査読者からの助言を取り入れ、さらに有害アニオン（ヒ素）の除去機能に関するデータも論文に追加した。
A01-1加藤らとの共同研究は、液晶超分子膜の選択的イオン輸送のキネティクスを窒化ガリウムデバイスを用いて計測した成果を論文として発表した（J Phys Chem B, supplementary cover）。A01-2辻らとスタートさせた水圏で作動する有機半導体分子層に関する研究については、単分子膜を実際のデバイスに転写した実験を行った。A03-3高島らとの選択的分子選択機能を駆使したメカノバイオ材料による幹細胞制御に関する研究成果もAdv Healthcare Mater (back cover) に論文として発表した。
共通機器であるQCM-Dを用いた公募班・芹澤との研究をACS Appl Biomater (front cover)に、また公募班・長谷川とEu錯体の水中自己会合体を用いたがん細胞検知に関する論文を発表するなど、公募班との共同研究成果を挙げることができた。

Research Progress Status

令和5年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

令和5年度が最終年度であるため、記入しない。

Research Products

• [Int'l Joint Research] コペンハーゲン大学(デンマーク)
• [Int'l Joint Research] ルンド大学(スウェーデン)
• [Int'l Joint Research] ハイデルベルク大学/カールスルーエ工科大学/ブレーメン大学(ドイツ)
• [Int'l Joint Research] ロレイン大学/ストラスブール大学(フランス)
• [Int'l Joint Research] 欧州分子生物学研究所（EMBL)(ドイツ)
• [Int'l Joint Research] ハイデルベルク大学 医学部 化学部(ドイツ)
• [Int'l Joint Research] ゲッチンゲン大学 物理学部(ドイツ)
• [Int'l Joint Research] カールスルーエ工科大学 生物学部(ドイツ)
• [Int'l Joint Research] 欧州分子生物学研究所（EMBL)/ハイデルベルク大学(ドイツ)
• [Int'l Joint Research] ストラスブルク大学(フランス)
• [Int'l Joint Research] ストラスブール大学/欧州放射光機構(フランス)
• [Int'l Joint Research] ハイデルベルク大学/カールスルーエ工科大学/ミュンヘン工科大学(ドイツ)
• [Int'l Joint Research] ストラスブール大学/ESRF(フランス)
• [Int'l Joint Research] ブルックヘブン国立研究所(米国)
• [Int'l Joint Research] ハイデルベルク大学(ドイツ)
• [Journal Article] Electrochemical Detection of Selective Anion Transport through Subnanopores in Liquid-Crystalline Water Treatment Membranes (2024)
  • Author(s): Mehlhose Sven、Sakamoto Takeshi、Eickhoff Martin、Kato Takashi、Tanaka Motomu
  • Journal Title: The Journal of Physical Chemistry B Volume: - Issue: 18 Pages: 4537-4543
  • DOI: 10.1021/acs.jpcb.4c00047
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Structure-changeable luminescent Eu(III) complex as a human cancer grade probing system for brain tumor diagnosis (2024)
  • Author(s): M. Wang, M. Kono, Y. Yamaguchi, J. Islam, S. Shoji, Y. Kitagawa, K. Fushimi, S. Watanabe, G. Matsuba, A. Yamamoto, M. Tanaka, M. Tsuda, S. Tanaka, Y. Hasegawa
  • Journal Title: Scientific Reports Volume: 14 Issue: 1 Pages: 778-778
  • DOI: 10.1038/s41598-023-50138-9
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Antibacterial Synthetic Nanocelluloses Synergizing with a Metal-Chelating Agent (2024)
  • Author(s): Takeshi Serizawa, Saeko Yamaguchi, Kai Sugiura, Ramona Marten, Akihisa Yamamoto, Yuuki Hata, Toshiki Sawada, Hiroshi Tanaka, and Motomu Tanaka
  • Journal Title: ACS Appl. Bio Mater. Volume: 7 Issue: 1 Pages: 246-255
  • DOI: 10.1021/acsabm.3c00846
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Reversible Host-Guest Crosslinks in Supramolecular Hydrogels for On‐Demand Mechanical Stimulation of Human Mesenchymal Stem Cells (2023)
  • Author(s): Linke Philipp、Munding Natalie、Kimmle Esther、Kaufmann Stefan、Hayashi Kentaro、Nakahata Masaki、Takashima Yoshinori、Sano Masaki、Bastmeyer Martin、Holstein Thomas、Dietrich Sascha、Muller‐Tidow Carsten、Harada Akira、Ho Anthony D.、Tanaka Motomu
  • Journal Title: Advanced Healthcare Materials Volume: 13 Issue: 10 Pages: 1-17
  • DOI: 10.1002/adhm.202302607
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Delivery of Probiotics and Enzymes in Self-assemblies of Lipids and Biopolymers Based on Colloidal Principles (2023)
  • Author(s): Jens Risbo, Tommy Nylander, and Motomu Tanaka
  • Journal Title: Front. Soft Matter Volume: 3
  • DOI: 10.3389/frsfm.2023.1257688
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Bio-Metamaterials for Mechano-Regulation of Mesenchymal Stem Cells (2023)
  • Author(s): Natalie Munding, Magdalena Fladung, Yi Chen, Marc Hippler, Anthony D. Ho, Martin Wegener, Martin Bastmeyer, and Motomu Tanaka
  • Journal Title: Adv. Funct. Mater Volume: 33 Issue: 20
  • DOI: 10.1002/adfm.202301133
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Thermodynamics and Viscoelastic Property of Interface Unravel Combined Functions of Cationic Surfactant and Aromatic Alcohol against Gram-Negative Bacteria (2023)
  • Author(s): Ippei Furikado, Taichi Habe, Shigeto Inoue, and Motomu Tanaka
  • Journal Title: Langmuir Volume: 39 Issue: 24 Pages: 8523-8531
  • DOI: 10.1021/acs.langmuir.3c00862
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Physical Biomarkers for Human Hematopoietic Stem and Progenitor Cells (2023)
  • Author(s): Motomu Tanaka, Judith Thoma, Laura Poisa-Beiro, Patrick Wuchter, Volker Eckstein, Sascha Dietrich, Caroline Pabst, Carsten Mueller-Tidow, Takao Ohta, and Anthony D. Ho
  • Journal Title: Cell & Development Volume: 174 Pages: 203845-203845
  • DOI: 10.1016/j.cdev.2023.203845
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Higher-Order Mesoscopic Self-Assembly of Fluorinated Surfactants on Water Surfaces (2023)
  • Author(s): Motomu Tanaka, Marie Pierre Krafft, and Andreea Pasc
  • Journal Title: NPG Asia Materials Volume: 15 Issue: 1
  • DOI: 10.1038/s41427-023-00466-z
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Wnt/β-catenin signaling induces axial elasticity patterns of Hydra extracellular matrix (2023)
  • Author(s): Veschgini Mariam、Suzuki Ryo、Kling Svenja、Petersen Hendrik O.、Bergheim Bruno Gideon、Abuillan Wasim、Linke Philipp、Kaufmann Stefan、Burghammer Manfred、Engel Ulrike、Stein Frank、?zbek Suat、Holstein Thomas W.、Tanaka Motomu
  • Journal Title: iScience Volume: 26 Issue: 4 Pages: 106416-106416
  • DOI: 10.1016/j.isci.2023.106416
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Modulation of wetting of stimulus responsive polymer brushes by lipid vesicles: experiments and simulations (2023)
  • Author(s): Weissenfeld Felix、Wesenberg Lucia、Nakahata Masaki、Mueller Marcus、Tanaka Motomu
  • Journal Title: Soft Matter Volume: 19 Issue: 14 Pages: 2491-2504
  • DOI: 10.1039/d2sm01673g
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Discreteness of cell?surface contacts affects spatio-temporal dynamics, adhesion, and proliferation of mouse embryonic stem cells (2022)
  • Author(s): Kimmle Esther、Hajian Foroushani Zahra、Keppler Stephan、Thoma Judith、Hayashi Kentaro、Yamamoto Akihisa、Bastmeyer Martin、Tanaka Motomu
  • Journal Title: Frontiers in Physics Volume: 10 Pages: 1-13
  • DOI: 10.3389/fphy.2022.1052106
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Stimulus-Responsive, Gelatin-Containing Supramolecular Nanofibers as Switchable 3D Microenvironments for Cells (2022)
  • Author(s): Hayashi Kentaro、Matsuda Mami、Nakahata Masaki、Takashima Yoshinori、Tanaka Motomu
  • Journal Title: Polymers Volume: 14 Issue: 20 Pages: 4407-4407
  • DOI: 10.3390/polym14204407
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Ion-specific nanoscale compaction of cysteine-modified poly(acrylic acid) brushes revealed by 3D scanning force microscopy with frequency modulation detection (2022)
  • Author(s): Yamamoto Akihisa、Ikarashi Takahiko、Fukuma Takeshi、Suzuki Ryo、Nakahata Masaki、Miyata Kazuki、Tanaka Motomu
  • Journal Title: Nanoscale Advances Volume: 4 Issue: 23 Pages: 5027-5036
  • DOI: 10.1039/d2na00350c
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Modulation of viscoelasticity and interfacial potential of polyelectrolyte brush by Ion-specific interactions (2022)
  • Author(s): Yamamoto Akihisa、Hayashi Kentaro、Sumiya Ai、Weissenfeld Felix、Hinatsu Satoko、Abuillan Wasim、Nakahata Masaki、Tanaka Motomu
  • Journal Title: Frontiers in Soft Matter Volume: 2 Pages: 1-14
  • DOI: 10.3389/frsfm.2022.959542
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Time-strain inseparability in multiaxial stress relaxation of supramolecular gels formed via host-guest interactions (2022)
  • Author(s): Kimura Takuro、Aoyama Takuma、Nakahata Masaki、Takashima Yoshinori、Tanaka Motomu、Harada Akira、Urayama Kenji
  • Journal Title: Soft Matter Volume: 18 Issue: 26 Pages: 4953-4962
  • DOI: 10.1039/d2sm00285j
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] One-Step Synthesis of Gelatin-Conjugated Supramolecular Hydrogels for Dynamic Regulation of Adhesion Contact and Morphology of Myoblasts (2022)
  • Author(s): Hayashi Kentaro、Matsuda Mami、Mitake Nodoka、Nakahata Masaki、Munding Natalie、Harada Akira、Kaufmann Stefan、Takashima Yoshinori、Tanaka Motomu
  • Journal Title: ACS Applied Polymer Materials Volume: 4 Issue: 4 Pages: 2595-2603
  • DOI: 10.1021/acsapm.1c01902
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Superiority of Mature Differentiated Cultured Human Corneal Endothelial Cell Injection Therapy for Corneal Endothelial Failure (2022)
  • Author(s): UENO MORIO、TODA MUNETOYO、NUMA KOHSAKU、TANAKA HIROSHI、IMAI KOJIRO、BUSH JOHN、TERAMUKAI SATOSHI、OKUMURA NAOKI、KOIZUMI NORIKO、YAMAMOTO AKIHISA、TANAKA MOTOMU、SOTOZONO CHIE、HAMURO JUNJI、KINOSHITA SHIGERU
  • Journal Title: American Journal of Ophthalmology Volume: 237 Pages: 267-277
  • DOI: 10.1016/j.ajo.2021.11.012
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Interplay of Trans- and Cis-Interactions of Glycolipids in Membrane Adhesion (2021)
  • Author(s): Kav Batuhan、Deme Bruno、Gege Christian、Tanaka Motomu、Schneck Emanuel、Weikl Thomas R.
  • Journal Title: Frontiers in Molecular Biosciences Volume: 8 Pages: 1-16
  • DOI: 10.3389/fmolb.2021.754654
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Water modulates the lamellar structure and interlayer correlation of poly(perfluorooctyl acrylate) films: a specular and off-specular neutron scattering study (2021)
  • Author(s): Yamamoto Akihisa、Higaki Yuji、Thoma Judith、Kimmle Esther、Ishige Ryohei、Dem? Bruno、Takahara Atsushi、Tanaka Motomu
  • Journal Title: Polymer Journal Volume: 54 Issue: 1 Pages: 57-65
  • DOI: 10.1038/s41428-021-00555-2
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Functionalized supported membranes for quantifying adhesion of P.?falciparum-infected erythrocytes (2021)
  • Author(s): Froehlich Benjamin、Dasanna Anil K.、Lansche Christine、Czajor Julian、Sanchez Cecilia P.、Cyrklaff Marek、Yamamoto Akihisa、Craig Alister、Schwarz Ulrich S.、Lanzer Michael、Tanaka Motomu
  • Journal Title: Biophysical Journal Volume: 120 Issue: 16 Pages: 3315-3328
  • DOI: 10.1016/j.bpj.2021.07.003
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Dendronized oligoethylene glycols with phosphonate tweezers for cell-repellent coating of oxide surfaces: coarse-scale and nanoscopic interfacial forces (2021)
  • Author(s): Julian Czajor, Wasim Abuillan, Dinh Vu Nguyen, Christopher Heidebrecht, Evan Angelo Mondarte, Oleg V Konovalov, Tomohiro Hayashi, Delphine Felder-Flesch, Stefan Kaufmann, Motomu Tanaka
  • Journal Title: RSC Advances Volume: 11 Issue: 29 Pages: 17727-17733
  • DOI: 10.1039/d1ra02571f
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] De Novo Synthesis of Free‐Standing Flexible 2D Intercalated Nanofilm Uniform over Tens of cm ² (2021)
  • Author(s): Ravat Prince、Uchida Hikaru、Sekine Ryosuke、Kamei Ko、Yamamoto Akihisa、Konovalov Oleg、Tanaka Motomu、Yamada Teppei、Harano Koji、Nakamura Eiichi
  • Journal Title: Advanced Materials Volume: - Issue: 22 Pages: 2106465-2106465
  • DOI: 10.1002/adma.202106465
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Critical role of lipid membranes in polarization and migration of cells: a biophysical view. (2021)
  • Author(s): Sackmann,E. & Tanaka, M.
  • Journal Title: Biophys Rev. Volume: 13 Issue: 1 Pages: 123-138
  • DOI: 10.1007/s12551-021-00781-1
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Ion-Mediated Cross-linking of Biopolymers Confined at Liquid/ Liquid Interfaces Probed by In Situ High-Energy Grazing Incidence X ray Photon Correlation Spectroscopy. (2020)
  • Author(s): Amadei, F.; Thomas, J.; Czajor, J.; Kimmle, E.; Yamamoto, A.; Abuillan,W.; Konovalov, O. V.; Chushkin, Y. & Tanaka, M.
  • Journal Title: J. Phys. Chem. B. Volume: 124 Issue: 40 Pages: 8937-8942
  • DOI: 10.1021/acs.jpcb.0c07056
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Mechanical stimulation of single cells by reversible host-guest interactions in 3D microscaffolds. (2020)
  • Author(s): Hippler, M.; Weissenbruch, K.; Richler, K.; Lemma, E. D.; Nakahata, M.; Richter, B.; Barner-Kowollik, C.; Takashima, Y.; Harada, A.; Blasco, E.; Wegener, M.; Tanaka, M. & Bastmeyer, M.
  • Journal Title: Sci. Adv. Volume: 6 Issue: 39 Pages: 1-13
  • DOI: 10.1126/sciadv.abc2648
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Stimuli-responsive hydrogels as a model of the dynamic cellular microenvironment (2020)
  • Author(s): Motomu Tanaka, Masaki Nakahata, Philipp Linke, Stefan Kaufmann
  • Journal Title: Polymer Journal Volume: - Issue: 8 Pages: 861-870
  • DOI: 10.1038/s41428-020-0353-6
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Editorial: Interfacial Water: A Physical Chemistry Perspective (2020)
  • Author(s): Tanaka Motomu、Seto Hideki
  • Journal Title: Frontiers in Chemistry Volume: 8 Pages: 760-760
  • DOI: 10.3389/fchem.2020.00760
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Specific localisation of ions in bacterial membranes unravels physical mechanism of effective bacteria killing by sanitizer. (2020)
  • Author(s): Thomas, J.; Abuillan, W.; Furikado, I.; Habe, T.; Yamamoto, A.; Gierlich, S.; Kaufmann, S.; Brandenburg, K.; Gutsmann, T.; Konobalov, O.; Inoue, S. & Tanaka, M.
  • Journal Title: Sci. Rep. Volume: 10 Issue: 1 Pages: 12302-12302
  • DOI: 10.1038/s41598-020-69064-1
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Nano-Focused Scanning X-ray Fluorescence Microscopy Reveals an Effect of Hemoglobin S and C on Biochemical Activities in P. falciparum-Infected Erythrocytes. (2020)
  • Author(s): Froehlich, B.; Yang, Y.; Thomas, J.; Czajor, J.; Lansche, C.; Sanchez, C.; Lanzer, M.; Cloetens, P. & Tanaka, M
  • Journal Title: Anal. Chem., Volume: 92 Issue: 8 Pages: 5765-5771
  • DOI: 10.1021/acs.analchem.9b05111
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Interplays of Interfacial Forces Modulate Structure and Function of Soft and Biological Matters in Aquatic Environments. (2020)
  • Author(s): Tanaka, M.
  • Journal Title: Front. Chem. Volume: 8 Pages: 165-165
  • DOI: 10.3389/fchem.2020.00165
  • NAID: 120006951654
  • Peer Reviewed / Open Access
• [Journal Article] Influence of Semifluorinated Alkane Surface Domains on Phase Behavior and Linear and Nonlinear Viscoelasticity of Phospholipid Monolayers. (2020)
  • Author(s): Mielke, S.; Liu, X.; Krafft, M. P. & Tanaka, M.
  • Journal Title: Langmuir Volume: 36 Issue: 3 Pages: 781-788
  • DOI: 10.1021/acs.langmuir.9b03521
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Presentation] 水圏機能材料の電子・イオン機能開拓 (2023)
  • Author(s): 田中 求
  • Organizer: 日本化学会CSJ化学フェスタ
• [Presentation] Bio-metamaterials: Mechanical Regulation of Single Mesenchymal Stem Cells by Unit Cell Arrangement (2023)
  • Author(s): 田中 求
  • Organizer: Metamaterials 2023:The 17th International Congress on Artificial Materials for Novel Wave Phenomena,
  • Int'l Joint Research / Invited
• [Presentation] Morphological dynamics of mouse pancreatic cells from different precancerous lesions (2023)
  • Author(s): 山本 暁久
  • Organizer: 28th International Conference on Statistical Physics, Statphys28
  • Int'l Joint Research / Invited
• [Presentation] 物理と数理で『測り』臨床医学につなげる細胞運動と組織秩序 (2023)
  • Author(s): 山本 暁久
  • Organizer: 2023年度統合講義「医学と数理及び工学」
  • Invited
• [Presentation] 異なる前癌病変に由来するマウス膵癌細胞変形運動ダイナミクス (2023)
  • Author(s): 山本 暁久
  • Organizer: 日本物理学会第78回年次大会
  • Invited
• [Presentation] 重金属イオン認識タンパク質を範とする生物着想型合成高分子の設計と水圏環境浄化への応用 (2023)
  • Author(s): 中畑 雅樹, 角谷 歩惟, 池本 夕佳, 中村 貴志, 山本 暁久, 境 慎司, Kaufmann Stefan, 田中 求
  • Organizer: 第72回高分子討論会
• [Presentation] 界面から解き明かす生命現象のダイナミクス (2022)
  • Author(s): 田中 求
  • Organizer: 第73回コロイドおよび界面科学討論会
  • Int'l Joint Research / Invited
• [Presentation] Spatio-temporal analysis of infected cells reveals the protection of HbS carriers from severe malari (2022)
  • Author(s): 田中 求
  • Organizer: 第三回「医学と数理」研究会 京大-ハイデルベルク大-理研ワークショップ 発表年
  • Int'l Joint Research
• [Presentation] Physical Modeling of Cell Surfaces: Interfacial Forces and Mechanics (2021)
  • Author(s): 田中 求
  • Organizer: Neutrons in Life Science and Biomaterials Swedish Neutron Graduate School (SWEDNESS)サマーシンポジウム
  • Int'l Joint Research / Invited
• [Presentation] 界面から読み解く抗菌・殺菌の物理化学：感染症と向き合う社会 に貢献する分析科学 (2021)
  • Author(s): 田中 求
  • Organizer: 大阪大学基礎工学研究科における次世代分析科学を考える会主催次世代分析化学へ向けてのセミナーシリーズ①
  • Invited
• [Presentation] Biological Interfaces out of Equilibrium - New Challenges in Soft Interface Science (2021)
  • Author(s): 田中 求
  • Organizer: Soft Interface Seminar九州大学・国際セミナーシリーズ
  • Int'l Joint Research / Invited
• [Presentation] Physics of Infectious Diseases (2021)
  • Author(s): 田中 求
  • Organizer: 日本生物物理学会
  • Invited
• [Presentation] 斜入射角X線を用いた界面微細構造・水圏静電相互作用・界面ダイナミクスの精密計測 (2021)
  • Author(s): 田中 求
  • Organizer: ソフト界面科学研究会
  • Invited
• [Presentation] 殺菌・抗菌の物理化学：界面から読み解くケミカルの機能 (2020)
  • Author(s): 田中 求
  • Organizer: 日本化学会秋季事業―第10回ＣＳＪ化学フェスタ2020
  • Invited
• [Presentation] “ヒト角膜内皮再生医療における細胞品質・予後予測の統合的バイオマーカーの開発 (2020)
  • Author(s): 山本 暁久, ;田中 求,
  • Organizer: 第69回高分子討論会
  • Invited
• [Presentation] Supported membranes as a platform for dynamic phenotyping of primary human cells: Quantifying the effect of intrinsic and extrinsic factors (2019)
  • Author(s): M.Tanaka
  • Organizer: American Chemical Society Spring Meeting
  • Int'l Joint Research / Invited
• [Presentation] Supported Membranes: Platform for Dynamic Phenotyping of Diseases (2019)
  • Author(s): M.Tanaka
  • Organizer: Institute Colloquium, Institute Charles Sadron
  • Int'l Joint Research / Invited
• [Presentation] Human Corneal Endothelium as 2D Colloidal Assembly (2019)
  • Author(s): M.Tanaka;A. Yamamoto
  • Organizer: Okinawa Colloid
  • Int'l Joint Research / Invited
• [Presentation] Nano-to-Meso Confinement Regulates the Fate of Cells (2019)
  • Author(s): M.Tanaka
  • Organizer: Debugging Nanibio-Interfaces to Promote Clinical Translation
  • Int'l Joint Research / Invited
• [Book] Cell-Inspired Materials and Engineering, Fundamental Biomedical Technologies (2022)
  • Author(s): Tanaka M.;Lanzer M.
  • Total Pages: 796
  • Publisher: Springer Nature
• [Book] Cell-Inspired Materials and Engineering, Fundamental Biomedical Technologies (2021)
  • Author(s): Tanaka, M.; Yamamoto, A.
  • Total Pages: 257
  • Publisher: Springer Nature
• [Patent(Industrial Property Rights)] イオン制御バイオデバイスとその製造方法 (2020)
  • Inventor(s): 山本 暁久；田中 求
  • Industrial Property Rights Holder: 山本 暁久；田中 求
  • Industrial Property Rights Type: 特許
  • Filing Date: 2020