Clarification of underlying factors involved in the establishment of sex differences

• Project Area: Molecular mechanisms for establishment of sex differences.
• Project/Area Number: 22132004
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: Hamamatsu University School of Medicine (2011-2014); National Research Institute for Child Health and Development (2010)
• Principal Investigator: OGATA TSUTOMU 浜松医科大学, 医学部, 教授 (40169173)
• Co-Investigator(Kenkyū-buntansha): FUKAMI Maki (独)国立成育医療研究センター研究所, 分子内分泌研究部, 部長 (40265872) ; TSUTSUI Kazuyoshi 早稲田大学, 教育・総合科学学術院, 教授 (20163842)
• Co-Investigator(Renkei-kenkyūsha): KAGAMI Masayo (独)国立成育医療研究センター研究所, 分子内分泌研究部, 室長 (70399484)
• Project Period (FY): 2010-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥181,740,000 (Direct Cost: ¥139,800,000、Indirect Cost: ¥41,940,000); Fiscal Year 2014: ¥33,540,000 (Direct Cost: ¥25,800,000、Indirect Cost: ¥7,740,000); Fiscal Year 2013: ¥35,490,000 (Direct Cost: ¥27,300,000、Indirect Cost: ¥8,190,000); Fiscal Year 2012: ¥37,440,000 (Direct Cost: ¥28,800,000、Indirect Cost: ¥8,640,000); Fiscal Year 2011: ¥37,050,000 (Direct Cost: ¥28,500,000、Indirect Cost: ¥8,550,000); Fiscal Year 2010: ¥38,220,000 (Direct Cost: ¥29,400,000、Indirect Cost: ¥8,820,000)
• Keywords: 性差構築 / ヒト疾患解析 / 性分化疾患 / 遺伝的制御 / 内分泌制御 / 性差 / ヒト疾患 / ゲノム / エピゲノム / 遺伝子機能 / MAMLD1 / ゲノム・エピゲノム解析 / 高密度アレイCGH解析 / 次世代シークエンサー解析 / 新規遺伝子 / POR / アロマターゼ過剰症 / 遺伝子型-表現型解析 / プロモーター

Outline of Final Research Achievements

Sex difference is established by genetic and endocrine regulations. We studied a large number (~1,000) of patient samples by next generation sequencing and array CGH analysis, and identified BHLHA9 as the novel genetic factor as well as the relevance of oligogenecity, and MAMLD1 and PROKR1 as the novel endocrine factors as well as the presence of an alternative androgen production route called backdoor pathway. We also clarified the essential role of gnih and other genes for the production of brain steroids (e.g., 7α-hydroxypregnenolone and estrogens) in the establishment of sex difference in reproductive, aggressive, and autonomous behaviors

Research Products

• [Journal Article] Hemodynamic assessment in a child with renovascular hypertension using time-resolved three-dimensional cine phase-contrast MRI (2015)
  • Author(s): Ishikawa T*, Takehara Y, Yamashita S, Iwashima S, Sugiyama M, Wakayama T, Johnson K, Wieben O, Sakahara H, Ogata T
  • Journal Title: J Magn Reson Imaging Volume: 41(1) Issue: 1 Pages: 165-168
  • DOI: 10.1002/jmri.24522
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] A 45,X/46,XY DSD (Disorder of Sexual Development) case with an extremely uneven distribution of 46,XY cells between lymphocytes and gonads (2015)
  • Author(s): Nomura R, Miyai K, Okada M, Kajiwara M, Ono M, Ogata T, Onishi I, Sato M, Sekine M, Akashi T, Mizutani S, Kashimada K
  • Journal Title: Clinical Pediatric Endocrinology Volume: 24 Issue: 1 Pages: 11-14
  • DOI: 10.1297/cpe.24.11
  • NAID: 130004853607
  • ISSN: 0918-5739, 1347-7358
  • Peer Reviewed
• [Journal Article] Silver-Russell syndrome without body asymmetry in three patients with duplications of maternally derived chromosome 11p15 involving CDKN1C (2015)
  • Author(s): Nakashima S, Kato F, Kosho T, Nagasaki K, Kikuchi T, Kagami M, Fukami M, Ogata T
  • Journal Title: J Hum Genet Volume: 60(2) Issue: 2 Pages: 91-95
  • DOI: 10.1038/jhg.2014.100
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Detecting copy number variations in whole exome sequencing data using exome hidden markov model - an expectation of “exome-first” approach. (2015)
  • Author(s): Miyatake S, Koshimizu E, Fujita A, Fukai R, Imagawa E, Ohba C, Kuki I, Makita Y, Ogata T, Nakashima M, Tsurusaki Y, Miyake N, Saitsu H, Matsumoto N
  • Journal Title: J Hum Genet Volume: 1 Issue: 4 Pages: 124-124
  • DOI: 10.1038/jhg.2014.124
  • Peer Reviewed / Open Access
• [Journal Article] Copy-number variations in Y chromosomal azoospermia factor regions identified by multiplex ligation-dependent probe amplification (2015)
  • Author(s): Saito K, Miyado M, Kobori Y, Tanaka Y, Ishikawa H, Yoshida A, Katsumi M, Saito H, Kubota T, Okada H, Ogata T, Fukami M
  • Journal Title: J Hum Genet Volume: 60(3) Issue: 3 Pages: 127-31
  • DOI: 10.1038/jhg.2014.115
  • Peer Reviewed
• [Journal Article] Comprehensive clinical studies in 34 patients with molecularly defined UPD(14)pat and related conditions (Kagami-Ogata syndrome) (2015)
  • Author(s): Kagami M, Kurosawa K, Miyazaki O, Ishino F, Matsuoka K, Ogata T
  • Journal Title: Eur J Hum Genet Volume: 2 Issue: 11 Pages: 1-8
  • DOI: 10.1038/ejhg.2015.13
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Novel splice site mutation in MAMLD1 in a patient with hypospadias. (2015)
  • Author(s): 10.1038/ejhg.2015.13
  • Journal Title: Sex Dev Volume: 3 Issue: 3 Pages: 1-1
  • DOI: 10.1159/000380842
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Molecular basis of non-syndromic hypospadias: Systematic mutation screening and genome-wide copy-number analysis of 62 patients. (2015)
  • Author(s): Kon M, Suzu ki E, Dung VC, Hasegawa Y, Mitsui T, Muroya K, Ueoka K, Igarashi N, Nagasaki K, Oto Y, Hamajima T, Yoshino K, Igarashi M, Kato-Fukui Y, Nakabayashi K, Hayashi K, Hata K, Matsubara Y, Moriya K, Ogata T, Nonomura K, Fukami M
  • Journal Title: Hum Reprod Volume: 30(3) Issue: 3 Pages: 499-506
  • DOI: 10.1093/humrep/deu364
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Impact of a novel homozygous mutation in nicotinamide nucleotide transhydrogenase on mitochondrial DNA integrity in a case of familial glucocorticoid deficiency. (2015)
  • Author(s): Fujisawa Y, Napoli E, Wong S, Song G, Yamaguchi R, Matsui T, Nagasaki K, Ogata T, Giulivi C
  • Journal Title: BBA clinical Volume: 3 Pages: 70-78
  • DOI: 10.1016/j.bbacli.2014.12.003
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] SOX3 overdosage permits normal sex development in females with random X inactivation (2015)
  • Author(s): Igarashi M, Mikami H, Katsumi M, Miyado M, Izumi Y, Ogata T, Fukami M
  • Journal Title: Sex Dev Volume: 3 Issue: 3 Pages: 1-1
  • DOI: 10.1159/000377653
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Microhomology-Mediated Microduplication in the Y Chromosomal Azoospermia Factor a (AZFa) Region in a Male with Mild Asthenozoospermia. (2015)
  • Author(s): Katsumi M, Ishikawa H, Tanaka Y, Saito K, Kobori Y, Okada H, Saito H, Nakabayashi K, Matsubara Y, Ogata T, Fukami M, Miyado M
  • Journal Title: Cytogenet Genome Res Volume: 3 Issue: 4 Pages: 1-1
  • DOI: 10.1159/000377649
  • Peer Reviewed
• [Journal Article] Lack of genomic rearrangements involving the aromatase gene CYP19A1 in breast cancer. (2014)
  • Author(s): Fukami M*, Suzuki J, Nakabayashi K, Tsunashima R, Ogata T, Shozu M, Noguchi S
  • Journal Title: Breast Cancer Volume: 21 (3) Issue: 3 Pages: 382-385
  • DOI: 10.1007/s12282-013-0471-5
  • Peer Reviewed
• [Journal Article] IMAGe syndrome: clinical and genetic implications based on Iinvestigations in three Japanese patients. (2014)
  • Author(s): Kato F, Hamajima T, Hasegawa T, Amano N, Horikawa R, Nishimura G, Nakashima S, Fuke T, Sano S, Fukami M, Ogata T
  • Journal Title: Clin Endocrinol Volume: 80 (5) Issue: 5 Pages: 706-713
  • DOI: 10.1111/cen.12379
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Genome-wide parent-of-origin DNA methylation analysis reveals the intricacies of the human imprintome and suggests a germline methylation independent establishment of imprinting. (2014)
  • Author(s): Court F, Tayama C, Romanelli V, Martin-Trujillo A, Iglesias-Platas I, Okamura K, Sugahara N, Simon C, Moore H, Harness J, Keirstead H, Vicente Sanchez-Mut J, Kaneki E, Lapunzina P, Soejima H, Wake N, Esteller M, Ogata T, Hata K, Nakabayashi K, Monk D*
  • Journal Title: Genome Res Volume: in press Issue: 4 Pages: 554-569
  • DOI: 10.1101/gr.164913.113
  • Peer Reviewed / Open Access
• [Journal Article] Identification and Functional Characterization of Two Novel NPR2 Mutations in Japanese Patients with Short Stature. (2014)
  • Author(s): Amano N, Mukai T, Ito Y, Narumi S, Tanaka T, Yokoya S, Ogata T, Hasegawa T*
  • Journal Title: J Clin Endocrinol Metab Volume: Epub ahead of print Issue: 4 Pages: E713-E718
  • DOI: 10.1210/jc.2013-3525
  • Peer Reviewed / Open Access
• [Journal Article] TBX1 Mutation Identified by Exome Sequencing in a Japanese Family with 22q11.2 Deletion Syndrome-like Craniofacial Features and Hypocalcemia. (2014)
  • Author(s): Ogata T*, Niihori T, Tanaka N, Kawai M, Nagashima T, Funayama R, Nakayama K, Nakashim S, Kato F, Fukami M, Aoki Y, Matsubara Y
  • Journal Title: PLoS One Volume: 9 Issue: 3 Pages: e91598-e91598
  • DOI: 10.1371/journal.pone.0091598
  • Peer Reviewed / Open Access
• [Journal Article] A missense single-nucleotide polymorphism in the sialic acid acetyl esterase gene is associated with anti–PIT-1 antibody syndrome. (2014)
  • Author(s): Yamamoto M, Iguchi G, Bando H, Fukuoka H, Suda K, Takahashi M, Nishizawa H, Matsumoto R, Tojo K, Mokubo A, Ogata T, Takahashi Y
  • Journal Title: Endocr J Volume: 61 (6) Pages: 641-644
  • Peer Reviewed / Open Access
• [Journal Article] Mutation Spectrum and Phenotypic Variation in Nine Patients with SOX2 abnormalities (2014)
  • Author(s): Suzuki J, Azuma N, Dateki S, Soneda S, Muroya K, Yamamoto Y, Saito R, Sano S, Nagai T, Wada H, Endo A, Urakami T, Ogata T, Fukami M
  • Journal Title: J Hum Genet Volume: 59 (6) Issue: 6 Pages: 353-356
  • DOI: 10.1038/jhg.2014.34
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Uniparental disomy of chromosome 8 leading to homozygosity of a CYP11B1 mutation in a patient with congenital adrenal hyperplasia: Implication for a rare etiology of an autosomal recessive disorder. (2014)
  • Author(s): Matsubara K, Kataoka N, Ogita S, Sano S, Ogata T, Fukami M*, Katsumata N
  • Journal Title: Endocr J Volume: 61 (6) Pages: 629-633
  • NAID: 130004770452
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Early vitamin K deficiency bleeding in a neonate associated with maternal Crohn's disease (2014)
  • Author(s): Ohishi A, Nakashima S, Ogata T, Iijima S
  • Journal Title: J Perinatol Volume: 34(8) Issue: 8 Pages: 636-639
  • DOI: 10.1038/jp.2014.64
  • Peer Reviewed
• [Journal Article] Rationale and study design of the Japan environment and children’s study (JECS) (2014)
  • Author(s): Kawamoto T, Nitta H, Murata K, Toda E, Tsukamoto N, Hasegawa M, Yamagata Z, Kayama F, Kshi R, Ohya Y, Saito H, Sago H, Okuyama M, Ogata T, Yokoya S, Koresawa Y, Shibata Y, Nakayama S, Michikawa T, Takeuchi A, Saitoh H
  • Journal Title: BMC Public Health Volume: 14 Issue: 1 Pages: 25-25
  • DOI: 10.1186/1471-2458-14-25
  • Peer Reviewed / Open Access
• [Journal Article] Comprehensive and quantitative multilocus methylation analysis reveals the susceptibility of specific imprinted differentially methylated regions (DMRs) to aberrant methylation in Beckwith-Wiedemann syndrome with epimutations (2014)
  • Author(s): Maeda T, Higashimoto K, Jozaki K, Hitomi H, Nakabayashi K, Makita Y, Tonoki H, Okamoto N, Takada F, Ohashi H, Migita M, Kosaki R, Matsubara K, Ogata T, Matsuo M, Hamasaki Y, Ohtsuka Y, Nishioka K, Joh K, Mukai T, Hata K, Soejima H
  • Journal Title: Genet Med Volume: 16(12) Issue: 12 Pages: 903-912
  • DOI: 10.1038/gim.2014.46
  • Peer Reviewed / Open Access
• [Journal Article] Genome-wide copy number analysis and systematic mutation screening in 58 patients with hypogonadotropic hypogonadism (2014)
  • Author(s): Izumi Y, Suzuki E, Kanzaki S, Yatsuga S, Kinjo S, Igarashi M, Maruyama T, Sano S, Horikawa R, Sato N, Nakabayashi K, Hata K, Umezawa A, Ogata T, Yoshimura Y, Fukami M
  • Journal Title: Fertil Steril Volume: 102(4) Issue: 4 Pages: 1130-1136
  • DOI: 10.1016/j.fertnstert.2014.06.017
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Clinical and molecular studies in four patients with SRY-positive 46,XX testicular disorders of sex development: implications for variable sex development and genomic rearrangements. (2014)
  • Author(s): Nakashima S, Oishi A, Takada F, Kawamura H, Igarashi M, Fukami M, Ogata T
  • Journal Title: J Hum Genet Volume: 59(10) Issue: 10 Pages: 549-553
  • DOI: 10.1038/jhg.2014.70
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Japanese founder duplications/triplications involving BHLHA9 are associated with split-hand/foot malformation with or without long bone deficiency and Gollop-Wolfgang complex. (2014)
  • Author(s): Nagata E, Kano H, Kato F, Yamaguchi R, Nakashima S, Takayama S, Kosaki R, Tonoki H, Mizuno S, Watanabe S, Yoshiura KI, Kosho T, Hasegawa T, Kimizuka M, Suzuki A, Shimizu K, Ohashi H, Haga N, Numabe H, Horii E, Nagai T, Yoshihashi H, Nishimura G, Toda T, et al.
  • Journal Title: Orphanet J Rare Dis Volume: 9 Issue: 1 Pages: 125-125
  • DOI: 10.1186/s13023-014-0125-5
  • Peer Reviewed / Open Access
• [Journal Article] Epimutations of the IG-DMR and the MEG3-DMR at the 14q32.2 imprinted region in two patients with Silver-Russell syndrome-compatible phenotype (2014)
  • Author(s): Kagami M, Mizuno S, Matsubars K, Nakabayashi K, Sano S, Fuke T, Fukami M, Ogata T
  • Journal Title: Eur J Hum Genet Volume: 11 Issue: 8 Pages: 1-6
  • DOI: 10.1038/ejhg.2014.234
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Hypogonadotropic hypogonadism in a female patient previously diagnosed as having Waardenburg syndrome due to a SOX10 mutation (2014)
  • Author(s): Izumi Y, Musha I, Suzuki E, Iso M, Jinno T, Horikawa R, Amemiya S, Ogata T, Fukami M, Ohtake A
  • Journal Title: Endocrine Volume: 10 Issue: 2 Pages: 1-1
  • DOI: 10.1007/s12020-014-0434-4
  • Peer Reviewed
• [Journal Article] A missense single-nucleotide polymorphism in the sialic acid acetylesterase (<i>SIAE</i>) gene is associated with anti&ndash;PIT-1 antibody syndrome (2014)
  • Author(s): Yamamoto M, Iguchi G, Bando H, Fukuoka H, Suda K, Takahashi M, Nishizawa H, Matsumoto R, Tojo K, Mokubo A, Ogata T, Takahashi Y
  • Journal Title: Endocrine Journal Volume: 61 Issue: 6 Pages: 641-644
  • DOI: 10.1507/endocrj.EJ13-0539
  • NAID: 130004770453
  • ISSN: 0918-8959, 1348-4540
  • Peer Reviewed / Open Access
• [Journal Article] Mutation Spectrum and Phenotypic Variation in Nine Patients with SOX2 abnormalities. (2014)
  • Author(s): Fukami M*, Suzuki J, Azuma N, Dateki S, Soneda S, Muroya K, Yamamoto Y, Saito R, Sano S, Nagai T, Wada H, Endo A, Urakami T, Ogata T:
  • Journal Title: J Hum Genet Volume: in press
  • Peer Reviewed
• [Journal Article] A missense single-nucleotide polymorphism in the sialic acid acetyl esterase gene is associated with anti-PIT-1 antibody syndrome. (2014)
  • Author(s): Yamamoto M, Iguchi G, Bando H, Fukuoka H, Suda K, Takahashi M, Nishizawa H, Matsumoto R, Tojo K, Mokubo A, Ogata T, Takahashi Y*
  • Journal Title: Endocr J Volume: in press
  • Peer Reviewed
• [Journal Article] Disorder of sex development in an infant with molecularly confirmed 46,XY, +der(10)t(10;21)(q21.1;q21.3), -21. (2014)
  • Author(s): Yagasaki H*, Nakane T, Saito T, Koizumi K, Kobayashi K, Ogata T
  • Journal Title: Am J Med Genet A Volume: 164 Issue: 3 Pages: 841-843
  • DOI: 10.1002/ajmg.a.36354
  • Peer Reviewed
• [Journal Article] Prenatal Genetic testing for a microdeletion at chromosome 14q32.2 imprinted region leading to upd(14)pat-like phenotype. (2014)
  • Author(s): Sasaki A, Sumie M, Eada S, Kosaki R, Kurosawa K, Fukami M, Sago H, Ogata T, Kagami M*
  • Journal Title: Am J Med Genet A Volume: 164A Issue: 1 Pages: 264-266
  • DOI: 10.1002/ajmg.a.36185
  • Peer Reviewed
• [Journal Article] A. Caraty, Differential expressions of RFamide-related peptide, a mammalian gonadotropin-inhibitory hormone ortholog, and kisspeptin in the hypothalamus of Abadeh ecotype does during breeding and anestrous seasons (2014)
  • Author(s): M. R. J. Shirazi, M. J. Zamiri, M. S. Salehi, S. Moradi, A. Tamadon, M. R. Namavar, A. Akhlaghi, K. Tsutsui
  • Journal Title: J. Neuroendocrinol Volume: in press
  • Peer Reviewed
• [Journal Article] Molecular basis for the activation of gonadotropin-inhibitory hormone gene transcription by corticosterone (2014)
  • Author(s): Y. L. Son, T. Ubuka, M. Narihiro, Y. Fukuda, I. Hasunuma, K. Yamamoto, D. D. Belsham, K. Tsutsui
  • Journal Title: Endocrinology Volume: in press
  • Peer Reviewed
• [Journal Article] Hypothalamic inhibition of socio-sexual behaviour by increasing neuroestrogen synthesis (2014)
  • Author(s): Takayoshi Ubuka, Shogo Haraguchi, Yasuko Tobari, Misato Narihiro, Kei Ishikawa, Takanori Hayashi, Nobuhiro Harada , Kazuyoshi Tsutsui
  • Journal Title: Nature Communications Volume: 5 Issue: 1 Pages: 3061-3061
  • DOI: 10.1038/ncomms4061
  • Peer Reviewed / Open Access
• [Journal Article] Breakthrough in neuroendocrinology by discovering novel neuropeptides and neurosteroids: 1) Discovery of gonadotropin-inhibitory hormone (GnIH) across vertebrates (2014)
  • Author(s): K. Tsutsui, T. Ubuka, Review
  • Journal Title: Gen. Comp. Endocrinol Volume: in press Pages: 4-10
  • DOI: 10.1016/j.ygcen.2014.03.006
  • Peer Reviewed
• [Journal Article] Breakthrough in neuroendocrinology by discovering novel neuropeptides and neurosteroids: 2) Discovery of neurosteroids and pineal neurosteroids (2014)
  • Author(s): K. Tsutsui, S. Haraguchi, Review
  • Journal Title: Gen. Comp. Endocrinol Volume: in press Pages: 11-22
  • DOI: 10.1016/j.ygcen.2014.03.008
  • Peer Reviewed
• [Journal Article] Gonadotropin-inhibitory hormone inhibits aggressive behavior of male quail by increasing neuroestrogen synthesis in the brain beyond its optimum concentration (2014)
  • Author(s): T. Ubuka, K. Tsutsui, Review
  • Journal Title: Gen. Comp. Endocrinol Volume: in press Pages: 49-54
  • DOI: 10.1016/j.ygcen.2014.03.014
  • Peer Reviewed
• [Journal Article] Biosynthesis and biological action of pineal allopregnanolone. (2014)
  • Author(s): K. Tsutsui, S. Haraguchi, Review
  • Journal Title: Front. Neurosci Volume: 5 Pages: 1-10
  • Peer Reviewed
• [Journal Article] Molecular evolution and function of 26RFa/QRFP and its cognate receptor (2014)
  • Author(s): K. Ukena, T. Osugi, J. Leprince, H. Vaudry, K. Tsutsui, Review
  • Journal Title: J. Mol. Endocrinol Volume: in press Issue: 3 Pages: T119-T131
  • DOI: 10.1530/jme-13-0207
  • Peer Reviewed
• [Journal Article] Central and direct regulation of testicular activity by gonadotropin-inhibitory hormone and its receptor (2014)
  • Author(s): T. Ubuka, Y. L. Son, Y. Tobari, M. Narihiro, G. E. Bentley, L. Kriegsfeld, K. Tsutsui
  • Journal Title: Front. Endocrinol. (Lausanne) Volume: VOL.5 Pages: 1-10
  • DOI: 10.3389/fendo.2014.00008
  • Peer Reviewed / Open Access
• [Journal Article] 化学掲示板‐女性ホルモンの量がオスの攻撃性を調整していた！ (2014)
  • Author(s): 筒井和義 総説
  • Journal Title: （1月18日日本経済新聞掲載）筒井和義教授（早稲田大学教育・総合科学学術院／先端生命医科学センター）に聞く、化学 Volume: 69 Pages: 73-73
  • Peer Reviewed
• [Journal Article] Aromatase excess syndrome in a family with upstream deletion of CYP19A1 (2013)
  • Author(s): Shihara D, Miyado M, Nakabayashi K, Shozu M, Nagasaki K, Ogata T, Fukami M*
  • Journal Title: Clin Endocrinol, Volume: Epub ahead of print Issue: 2 Pages: 314-316
  • DOI: 10.1111/cen.12329
  • Peer Reviewed
• [Journal Article] De novo frameshift mutation in fibroblast growth factor 8 in a male patient with gonadotropin deficiency (2013)
  • Author(s): Suzuki E, Yatsuga S, Igarashi M, Miyado M, Nakabayashi K, Hayashi K, Hata K, Umezawa A, Yamada G, Ogata T, Fukami M*
  • Journal Title: Horm Res Paediatr , Volume: 81 Issue: 2 Pages: 139-144
  • DOI: 10.1159/000355380
  • Peer Reviewed / Open Access
• [Journal Article] A novel de novo point mutation of OCT-binding site in the IGF2/H19-imprinting control region in a patient with Beckwith-Wiedemann syndrome. (2013)
  • Author(s): Higashimoto K, Jozaki K, Kosho T, Matsubara K, Sato T, Yamada D, Yatsuki H, Maeda T, Ohtsuka Y, Nishioka K, Joh K, Koseki H, Ogata T, SoejimaH*
  • Journal Title: Clin Genet Volume: in press Issue: 6 Pages: 539-544
  • DOI: 10.1111/cge.12318
  • Peer Reviewed / Open Access
• [Journal Article] Backdoor pathway for dihydrotestosterone biosynthesis: implications for normal and abnormal human sex development. (2013)
  • Author(s): Fukami M, Homma K, Hasegawa T, Ogata T*
  • Journal Title: Dev Dyn , Volume: 4 Issue: 4 Pages: 320-329
  • DOI: 10.1002/dvdy.23892
  • Peer Reviewed
• [Journal Article] Comprehensive and quantitative multilocus methylation analysis reveals the susceptibility of specific imprinted differentially methylated regions (DMRs) to aberrant methylation in Beckwith-Wiedemann syndrome with epimutations. (2013)
  • Author(s): Maeda T, Higashimoto K, Jozaki K, Yatsuki H, Nakabayashi K, Makita Y, Tonoki H, Okamoto N, Takada F, Ohashi H, Migita M, Kosaki R, Matsubara K, Ogata T, Matsuo M, Hamasaki Y, Ohtsuka Y, Nishioka K, Joh K, Mukai T, Hata K, Soejima H*
  • Journal Title: Genet Med Volume: in press
  • Peer Reviewed
• [Journal Article] Genomic basis of aromatase excess syndrome: recombination- and replication-mediated rearrangements leading to CYP19A1 overexpression. (2013)
  • Author(s): Fukami M*, Tsuchiya T, Vollbach H, Brown KA, Abe S, Ohtsu S, Wabitsch M, Gurger H, Sompson ER, Emezawa A, Nakabayashi K, Bulun SE, Shozu M, Ogata T
  • Journal Title: J Clin Endocrinol Metab Volume: 98 Issue: 12 Pages: E2013-E2021
  • DOI: 10.1210/jc.2013-2520
  • Peer Reviewed
• [Journal Article] Compound heterozygous deletions in pseudoautosomal region 1 in an infant with mild manifestsations of Langer mesomelic dysplasia. (2013)
  • Author(s): Tsuchiya T, Shibata M, Numabe H, Jinnno T, Nakabayashi K, Nishimura G, Nagai T, Ogata T, Fukami M*
  • Journal Title: Am J Med Genet A Volume: in press Issue: 2 Pages: 505-510
  • DOI: 10.1002/ajmg.a.36284
  • Peer Reviewed
• [Journal Article] Critical role of Yp inversion in PRKX/PRKY-mediated Xp;Yp translocation in a patient with 45,X testicular disorder of sex development. (2013)
  • Author(s): Nakashima S, Watanabe Y, Okada J, Ono H, Nagata E, Fukami M, Ogata T*
  • Journal Title: Endocr J Volume: 60 Pages: 1329-1334
  • NAID: 130004770409
  • Peer Reviewed
• [Journal Article] Long term follow up study for a patient with Floating-Harbor syndrome due to a hotspot SRCAP mutation. (2013)
  • Author(s): Nagasaki K*, Asami T, Sato H, Ogawa Y, Kikuchi T, Saitoh A, Ogata T, Fukami M
  • Journal Title: Am J Med Genet A, Volume: 164 Issue: 3 Pages: 731-735
  • DOI: 10.1002/ajmg.a.36314
  • Peer Reviewed
• [Journal Article] Identification of AP2S1 Mutation and Effects of Low Calcium Formula in an Infant with Hypercalcemia and Hypercalciuria. (2013)
  • Author(s): Fujisawa Y*, Yamaguchi R, Satake E, Ohtaka K, Nakanishi T, Ozono K, Ogata T
  • Journal Title: J Clin Endocrinol Metab Volume: 98 Issue: 12 Pages: E2022-E2027
  • DOI: 10.1210/jc.2013-2571
  • Peer Reviewed
• [Journal Article] The lipid fraction of human milk initiates adipocyte differentiation in 3T3-L1 cells. (2013)
  • Author(s): Fujisawa Y*, Yamaguchi R, Nagata E, Satake E, Sano S, Matsushita R, Kitsuta K, Nakashima S, Nakanishi T, Nakagawa Y, Ogata T
  • Journal Title: Early Hum Dev Volume: Epub ahead of print Issue: 9 Pages: 713-719
  • DOI: 10.1016/j.earlhumdev.2013.05.002
  • Peer Reviewed
• [Journal Article] A 68-year-old phenotypically male patient with 21-hydroxylase deficiency and concomitant adrenocortical neoplasm producing testosterone and cortisol. (2013)
  • Author(s): Hayashi M*, Kataoka Y, Sugimura Y, Kato F, Fukami M, Ogata T, Homma K, Hasegawa T, Oiso Y, Sasano H, Tanaka H
  • Journal Title: Tohoku J Exp Med Volume: 231 Pages: 75-84
  • NAID: 130004720753
  • Peer Reviewed
• [Journal Article] Cryptic genomic rearrangements in three patients with 46,XY disorders of sex development. (2013)
  • Author(s): Igarashi M, Dung VC, Suzuki E, Ida S, Nakacho M, Nakabayashi K, Mizuno K, Hayashi Y, Kohri K, Kojima Y, Ogata T, Fukami M*
  • Journal Title: PLoS One Volume: 8
  • Peer Reviewed
• [Journal Article] Gain-of-function mutations in RIT1 cause Noonan syndrome, a RAS/MAPK pathway syndrome. (2013)
  • Author(s): Aoki Y*, Niihori T, Banjo T, Okamoto N, Mizuno S, Kurosawa K, Ogata T, Takada F, Yano M, Ando T, Hoshika T, Barnett C, Ohashi H, Kawame H, Hasegawa T, Okutani T, Nagashima T, Hasegawa S, Funayama R, Nagashima T, Nakayama K, Inoue S, Watanabe Y, Ogura T, Matsubara Y
  • Journal Title: Am J Hum Genet Volume: 93 Pages: 173-180
  • Peer Reviewed
• [Journal Article] Glucose-6-phosphate dehydrogenase deficiency and adrenal hemorrhage in a Filipino neonate with hyperbilirubinemia. (2013)
  • Author(s): Ohishi A*, Ueno D, Ogata T
  • Journal Title: AJP Rep Volume: 3 Issue: 01 Pages: 5-8
  • DOI: 10.1055/s-0032-1329125
  • Peer Reviewed
• [Journal Article] MLL2 and KDM6A mutations in patients with Kabuki syndrome. (2013)
  • Author(s): Miyake N*, Koshimizu E, Okamoto N, Mizuno S, Ogata T,at all
  • Journal Title: Am J Med Genet A Volume: 161 Issue: 9 Pages: 2234-2243
  • DOI: 10.1002/ajmg.a.36072
  • Peer Reviewed
• [Journal Article] Human glutathione S-transferase A (GSTA) family genes are regulated by steroidogenic factor 1 (SF-1) and are involved in steroidogenesis. (2013)
  • Author(s): Matsumura T, Imamichi Y, Mizutani T, Ju Y, Yazawa T, Kawabe S, Kanno M, Ayabe T, Katsumata N, Fukami M, Inatani M, Akagi Y, Umezawa A, Ogata T, Miyamoto K
  • Journal Title: FASEB J Volume: 27 Issue: 8 Pages: 3198-3208
  • DOI: 10.1096/fj.12-222745
  • Peer Reviewed
• [Journal Article] Submicroscopic deletion involving the fibroblast growth factor receptor 1 gene in a patient with combined pituitary hormone deficiency. (2013)
  • Author(s): Fukami M*, Iso M, Sato N, Igarashi M, Seo M, Kazukawa I, Kinoshita E, Dateki S, Ogata T
  • Journal Title: Endocr J Volume: 60 Pages: 1013-1020
  • NAID: 10031195771
  • Peer Reviewed
• [Journal Article] A novel homozygous mutation of the nicotinamide nucleotide transhydrogenase gene in a Japanese patient with familial glucocorticoid deficiency. (2013)
  • Author(s): Yamaguchi R, Kato F, Hasegawa T, Katsumata N, Fukami M, Matsui T, Nagasaki K, Ogata T
  • Journal Title: Endocr J Volume: 60 Pages: 855-859
  • NAID: 10031195753
  • Peer Reviewed
• [Journal Article] Birth seasonality in Prader-Willi syndrome resulting from chromosome 15 microdeletion. (2013)
  • Author(s): Ayabe T, Matsubara K, Ogata T, Ayabe A, Murakami N, Nagai T, Fukami M*
  • Journal Title: Am J Med Genet A Volume: 161 Issue: 6 Pages: 1495-1497
  • DOI: 10.1002/ajmg.a.35893
  • Peer Reviewed
• [Journal Article] Molecular and clinical studies in 138 Japanese patients with Silver-Russell syndrome. (2013)
  • Author(s): Fuke T, Mizuno S, Nagai T, Hasegawa T, Horikawa R, Miyoshi Y, Muroya K, Kondoh T, Numakura C, Sato S, Nakabayashi K, Tayama C, Hata K, Sano S, Matsubara K, Kagami M, Yamazawa K, Ogata T*
  • Journal Title: PLoS One Volume: 8
  • Peer Reviewed
• [Journal Article] Neuromuscular symptoms in a patient with familial pseudohypoparathyroidism type Ib diagnosed by methylation-specific multiplex ligation-dependent probe amplification. (2013)
  • Author(s): Nagasaki K*, Tsuchuya S, Saitoh A, Ogata T, Fukami M
  • Journal Title: Endocr J Volume: 60 Pages: 231-236
  • NAID: 10031156746
  • Peer Reviewed
• [Journal Article] A report of two novel NR5A1 mutation families: possible clinical phenotype of psychiatric symptoms of anxiety and/or depression. (2013)
  • Author(s): Suzuki-Suwanai A, Ishii T, Haruna H, Yamataka A, Narumi S, Fukuzawa R, Ogata T, Hasegawa T*
  • Journal Title: Clin Endocrinol Volume: 78 Issue: 6 Pages: 957-965
  • DOI: 10.1111/cen.12054
  • Peer Reviewed
• [Journal Article] 性分化疾患の性自認に関する調査研究 (2013)
  • Author(s): 大山建司，深見真紀，緒方勤
  • Journal Title: 日小児会誌 Volume: 117 Pages: 1403-1409
  • NAID: 10031195068
  • Peer Reviewed
• [Journal Article] 新規男性ホルモン産生経路：正常性分化および性分化疾患発症における役割 (2013)
  • Author(s): 深見真紀，緒方勤
  • Journal Title: 細胞工学（特集：性決定分化の制御システム） Volume: 32 Pages: 193-198
  • Peer Reviewed
• [Journal Article] 性分化疾患の検査の進め方 (2013)
  • Author(s): 緒方勤
  • Journal Title: 小児内科（特集：負荷試験の実際） Volume: 45 Pages: 815-820
  • Peer Reviewed
• [Journal Article] Aromatase excess syndrome: a rare autosomal dominant disorder leading to pre- or peri-pubertal onset gynecomastia. (2013)
  • Author(s): Fukami M*, Miyado M, Nagasaki K, Shozu M, Ogata T
  • Journal Title: Pediatr Endocr Rev Volume: 11 Pages: 298-305
  • Peer Reviewed
• [Journal Article] Advanced maternal age at childbirth and the development of uniparental disomy. A commentary on the proportion of uniparental disomy is increased in Prader-Willi syndrome due to an advanced maternal childbearing age in Korea. (2013)
  • Author(s): Matsubara K, Ogata T*
  • Journal Title: J Hum Genet Volume: 58 Issue: 3 Pages: 118-119
  • DOI: 10.1038/jhg.2013.4
  • NAID: 10031164067
  • Peer Reviewed
• [Journal Article] Contribution of de novo synthesis of Gas proteins to 1-methyladenine production in starfish ovarian follicle cells stimulated by relaxin-like gonad-stimulating substance (2013)
  • Author(s): Masatoshi Mita, Shogo Haraguchi, Haruka Uzawa, Kazutoshi Tsutsui
  • Journal Title: Biochemical and Biophysical Research Communications Volume: 440 Issue: 4 Pages: 798-801
  • DOI: 10.1016/j.bbrc.2013.10.038
  • Peer Reviewed
• [Journal Article] Molecular evolution of Kiss2 genes and peptides in vertebrates (2013)
  • Author(s): T. Osugi, N. Ohtaki, Y. Sunakawa, Y. L. Son, M. Ohkubo, M. Iigo, M. Amano, K. Tsutsui
  • Journal Title: Endocrinology Volume: VOL.154 Issue: 11 Pages: 4270-4280
  • DOI: 10.1210/en.2012-2267
  • Peer Reviewed
• [Journal Article] Gonadotropin-inhibitory hormone reduces sexual motivation but not lordosis behavior in female Syrian hamsters (Mesocricetus auratus) (2013)
  • Author(s): D. J. Piekarski, S. Zhao, K. J. Jennings, T. Iwasa, S. J. Legan, J. D. Mikkelsen, K. Tsutsui, L. J. Kriegsfeld
  • Journal Title: Horm. Behav Volume: 64 Issue: 3 Pages: 501-510
  • DOI: 10.1016/j.yhbeh.2013.06.006
  • Peer Reviewed
• [Journal Article] A genetically female brain is required for a regular reproductive cycle in chicken brain chimeras (2013)
  • Author(s): Fumihiko Maekawa
  • Journal Title: Nature Communications Volume: 4 Issue: 1 Pages: 1372-1372
  • DOI: 10.1038/ncomms2372
  • Peer Reviewed
• [Journal Article] Contribution of Leydig and Sertoli cells to testosterone production in mouse fetal testes (2013)
  • Author(s): Y. Shima, K. Miyabayashi, S. Haraguchi, T. Arakawa, H, Otake, T. Baba, S. Matsuzaki, Y. Shishido, H. Akiyama, T. Tachibana, K. Tsutsui, K. Morohashi
  • Journal Title: Mol. Endocrinol Volume: 27 Pages: 63-67
  • Peer Reviewed
• [Journal Article] Biosynthesis and biological actions of pineal neurosteroids in domestic birds, [Selected for Issue Cover] (2013)
  • Author(s): K. Tsutsui, S. Haraguchi, M. Hatori, T. Hirota, Y. Fukada, Review
  • Journal Title: Neuroendocrinology Volume: 98 Issue: 2 Pages: 97-105
  • DOI: 10.1159/000353782
  • Peer Reviewed
• [Journal Article] New biosynthesis and biological actions of avian neurosteroids (2013)
  • Author(s): K. Tsutsui, S. Haraguchi, K. Inoue, H. Miyabara, T. Ubuka, M. Hatori, T. Hirota, Y. Fukada, Review
  • Journal Title: J. Exp. Neurosci Volume: 7 Pages: 15-29
  • DOI: 10.4137/jen.s11148
  • Peer Reviewed
• [Journal Article] 10th International Symposium on Avian Endocrinology (2013)
  • Author(s): K. Tsutsui, P. J. Sharp, R. M. Dores, Review
  • Journal Title: Gen. Comp. Endocrinol Volume: 190 Pages: 1-2
  • Peer Reviewed
• [Journal Article] Regulatory mechanisms of gonadotropin-inhibitory hormone (GnIH) synthesis and release in photoperiodic animals (2013)
  • Author(s): K. Tsutsui, T. Ubuka, G. E. Bentley, L. Kriegsfeld, Review
  • Journal Title: Front. Neurosci Volume: 7 Pages: 1-11
  • DOI: 10.3389/fnins.2013.00060
  • Peer Reviewed
• [Journal Article] Neuroendocrine regulation of gonadotropin secretion in seasonally breeding birds (2013)
  • Author(s): T. Ubuka, G. E. Bentley, K. Tsutsui, Review
  • Journal Title: Front. Neurosci Volume: 7 Pages: 1-17
  • DOI: 10.3389/fnins.2013.00038
  • Peer Reviewed
• [Journal Article] Brain and pineal 7α-hydroxypregnenolone stimulating locomotor activity : Identification, mode of action and regulation of biosynthesis (2013)
  • Author(s): Kazuyoshi Tsutsui, Shogo Haraguchi, Yoshitaka Fukada, Hubert Vaudry
  • Journal Title: Frontiers in Neuroendocrinology Volume: 34 Issue: 3 Pages: 179-189
  • DOI: 10.1016/j.yfrne.2013.05.002
  • Peer Reviewed
• [Journal Article] dentification, localization and function of a novel neuropeptide, 26RFa, and its cognate receptor, GPR103 in the avian hypothalamus (2013)
  • Author(s): K. Ukena, T. Tachibana, Y. Tobari, J. Leprince, H. Vaudry, K. Tsutsui, Review
  • Journal Title: Gen. Comp. Endocrinol Volume: 190 Pages: 42-46
  • Peer Reviewed
• [Journal Article] Review : Gonadotropin-inhibitory hormone (GnIH), GnIH receptor and cell signaling (2013)
  • Author(s): T. Ubuka, Y. L. Son, G. E. Bentley, R. P. Millar, K. Tsutsui
  • Journal Title: Gen. Comp. Endocrinol. Volume: VOL.190 Pages: 10-17
  • DOI: 10.1016/j.ygcen.2013.02.030
  • Peer Reviewed
• [Journal Article] RNA interference of gonadotropin-inhibitory hormone gene induces aggressive and sexual behaviors in birds (2013)
  • Author(s): T. Ubuka, T. Mizuno, Y. Fukuda, G. E. Bentley, J. C. Wingfield, K. Tsutsui, Review
  • Journal Title: Gen. Comp. Endocrinol Volume: 181 Pages: 179-186
  • DOI: 10.1016/j.ygcen.2012.09.010
  • Peer Reviewed
• [Journal Article] Melatonin stimulates the synthesis and release of gonadotropin-inhibitory hormone in birds (2013)
  • Author(s): V. S. Chowdhury, T. Ubuka, K. Tsutsui, Review
  • Journal Title: Gen. Comp. Endocrinol Volume: 181 Pages: 175-178
  • DOI: 10.1016/j.ygcen.2012.08.005
  • Peer Reviewed
• [Journal Article] Create new research directions in comparative endocrinology from Asia and Oceania (2013)
  • Author(s): K. Tsutsui, Review
  • Journal Title: Gen. Comp. Endocrinol Volume: 181 Pages: 192-196
  • DOI: 10.1016/j.ygcen.2012.04.015
  • Peer Reviewed
• [Journal Article] ハムスターのGnIHの同定及び発現制御と生理機能の解析 (2013)
  • Author(s): 産賀崇由、井上和彦、筒井和義、総説
  • Journal Title: 生殖内分泌学会雑誌 Volume: 18 Pages: 27-33
  • Peer Reviewed
• [Journal Article] ：松果体で合成・放出されたアロプレグナノロンは発達期の小脳プルキンエ細胞の生存に不可欠である (2013)
  • Author(s): 原口省吾、原桜子、産賀崇由、三田雅敏、筒井和義、総説
  • Journal Title: 比較内分泌学 Volume: 39 Pages: 44-48
  • NAID: 130004952311
  • Peer Reviewed
• [Journal Article] 46, XY gonadal dysgenesis : new SRY point mutation in two siblings with paternal germ line mosaicism (2012)
  • Author(s): Stoppa-Vaucher S, Ogata T, et al
  • Journal Title: Clin Genet Volume: (in press)(Epub ahead of print) Issue: 6 Pages: 505-513
  • DOI: 10.1111/j.1399-0004.2011.01832.x
  • Peer Reviewed
• [Journal Article] Two-step biochemical differential diagnosis of classic 21-hydroxylase deficiency and coytochrome P450 oxidoreductase deficiency in Japanese infants by GC-MS measurement (2012)
  • Author(s): Y.Koyama, K.Homma, M.Fukami, M.Miwa, K.Ikeda, T.Ogata, et al
  • Journal Title: Clin.Chem. Volume: 58 Issue: 4 Pages: 741-747
  • DOI: 10.1373/clinchem.2011.173286
  • Peer Reviewed
• [Journal Article] Screening of MAMLD1 mutations in 70 Children with 46,XY DSD: Identification and functional analysis of two new mutations. (2012)
  • Author(s): N. Kalfa, M. Fukami, P. Philibert, F. Audran, C. Pienkowski, G. Weill, C. Pinto, S. Manouvrier, M. Polak, T. Ogata, C. Sultan.
  • Journal Title: PLoS One Volume: 7 Issue: 3 Pages: e32505-e32505
  • DOI: 10.1371/journal.pone.0032505
  • Peer Reviewed
• [Journal Article] Identification of novel low-dose bisphenol A targets in human foreskin fibroblast cells derived from hypospadias patients. (2012)
  • Author(s): Qin X-Y, Miyado M, Kojima Y, Zaha H Akanuma H, Zeng Q, Yoshinaga J, Yonemoto J, Fukami M, Ogata T, Sone H*
  • Journal Title: PLoS ONE Volume: 7 (5)
  • Peer Reviewed
• [Journal Article] Complex genomic rearrangements in the SOX9 5' region in a patient with Pierre Robin sequence and hypoplastic left scapula. (2012)
  • Author(s): M. Fukami, T. Tsuchiya, S. Takada, A. Kanbara, H. Asahara, A. Igarashi, Y. Kamiyama, G. Nishimura, T. Ogata.
  • Journal Title: Am. J. Med. Genet. A. Volume: 158A Issue: 7 Pages: 1529-1534
  • DOI: 10.1002/ajmg.a.35308
  • Peer Reviewed
• [Journal Article] Mutations in PRRT2 responsible for paroxysmal kinesigenic dyskinesias also cause benign familialinfantile convulsions. (2012)
  • Author(s): Ono S, Yoshiura K , KinoshitaA, Kikuchi T, Nakane Y, Kato N,Sadamatsu M , Konishi T , Nagamitsu S , Matsuura M, Yasuda A, KomineM, Kanai K , Inoue T , Osamura T , Saito K , Hirose S, Koide H, Tomita H , Ozawa H , Niikawa N and Kurotaki N.
  • Journal Title: J Hum Genet Volume: 57 Issue: 5 Pages: 1-4
  • DOI: 10.1038/jhg.2012.23
  • Peer Reviewed
• [Journal Article] Association of variants in genes involved in environmental chemical metabolism and risk of cryptorchidism and hypospadias. (2012)
  • Author(s): X.Y. Qin, Y. Kojima, K. Mizuno, K. Ueoka, F. Massart, C. Spinelli, H. Zaha, M. Okura, J. Yoshinaga, J. Yonemoto, K. Kohri, Y. Hayashi, T. Ogata, H. Sone.
  • Journal Title: J. Hum. Genet. Volume: 57 Issue: 7 Pages: 434-441
  • DOI: 10.1038/jhg.2012.48
  • NAID: 10030965639
  • Peer Reviewed
• [Journal Article] PRKAR1A mutation affecting cAMP-mediated G-protein-coupled receptor signaling in a patient with acrodysostosis and hormone resistance. (2012)
  • Author(s): Nagasaki K, Iida T, Sato H, Ogawa Y, Kikuchi T, Saitoh A, Ogata T*, Fukami M
  • Journal Title: J Clin Endocrinol Metab Volume: 97 (9)
  • Peer Reviewed
• [Journal Article] Individual variation of the genetic response to low-dose bisphenol A in human foreskin fibroblast cells derived from cryptorchidism and hypospadias patients. (2012)
  • Author(s): Qin XY, Sone H*, Kojima Y, Ueoka K, Muroya K, Miyado M, Zaha H, Fukuda T, Yoshinaga J, Yonemoto J, Fukami M, Ogata T
  • Journal Title: PLoS One Volume: 7 (12)
  • Peer Reviewed
• [Journal Article] Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. (2012)
  • Author(s): Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, , Ogata T*
  • Journal Title: Endocrinology Volume: accepted
  • Peer Reviewed
• [Journal Article] Mutation and deletion of fibroblast growth factor receptor 1 gene in two patients with combined pituitary hormone deficiency. (2012)
  • Author(s): Fukami M*, Iso M, Sato N, Igarashi M, Seo M, Kazukawa I, Kinoshita E, Dateki S, Ogata T
  • Journal Title: Endocr J Volume: accepted
  • Peer Reviewed
• [Journal Article] Review : Molecular bases and phenotypic determinants of aromatase excess syndrome (2012)
  • Author(s): M.Fukami, M.Shozu, T.Ogata, et al
  • Journal Title: Int.J.Endocrinol. Volume: (印刷中)(in～press) Pages: 584807-584807
  • DOI: 10.1155/2012/584807
  • Peer Reviewed
• [Journal Article] Review: MAMLD1 and 46,XY disorders of sex development. (2012)
  • Author(s): T. Ogata, S. Sano, E. Nagata, F. Kato, M. Fukami.
  • Journal Title: Semi. Reprod. Med. Volume: 30 Issue: 05 Pages: 410-416
  • DOI: 10.1055/s-0032-1324725
  • Peer Reviewed
• [Journal Article] 性分化疾患 (2012)
  • Author(s): 緒方勤
  • Journal Title: 臨床と研究（特集：小児診療のピットフォールII） Volume: 89 (5) Pages: 53-58
• [Journal Article] 性分化疾患 (2012)
  • Author(s): 緒方勤
  • Journal Title: 小児科（小児疾患の診断治療基準） Volume: 44 (増刊号) Pages: 218-219
• [Journal Article] 子どもの健康と環境ホルモン：男児外陰部異常をモデルとして (2012)
  • Author(s): 緒方勤
  • Journal Title: 小児科臨床 Volume: 65 （増刊号：小児の中毒） Pages: 1565-1572
• [Journal Article] 原発性性線機能低下症．大関武彦，古川漸，横田俊一郎，水口雅 (2012)
  • Author(s): 緒方勤
  • Journal Title: 今日の小児治療指針 Volume: 15版 Pages: 244-245
• [Journal Article] 心血管病変発症の性差とY染色体 (2012)
  • Author(s): 緒方勤
  • Journal Title: MMJ Volume: 8 (4) Pages: 190-191
• [Journal Article] Identification of a novel mutation in the exon 2 splice donor site of the POU1F1/PIT-1 gene in Japanese identical twins with mild combined pituitary hormone deficiency (2012)
  • Author(s): Inoue H, Ogata T, et al
  • Journal Title: Clin Endocrinol Volume: 76(1) Pages: 78-87
  • Peer Reviewed
• [Journal Article] Genetic characteristics on HLA-cass IT and class I among Japanese type 1A and type 1B diabetic children and their families (2012)
  • Author(s): Sugihara S, Ogata T, et al
  • Journal Title: Pediatr Diabetes Volume: 13(1) Pages: 33-44
  • Peer Reviewed
• [Journal Article] Relative frequency of underlying genetic causes for the development of UPD(14)pat-like phenotype (2012)
  • Author(s): Kagami M, Ogata T, et al
  • Journal Title: Eur J Hum Genet Volume: (accepted)(Epub ahead of print) Issue: 9 Pages: 928-932
  • DOI: 10.1038/ejhg.2012.26
  • Peer Reviewed
• [Journal Article] Mosaic upd(7)mat in a patient with Silver-Russell syndrome : correlation between phenotype and mosaic ratio in the body and the placenta (2012)
  • Author(s): Fuke-Sato T, Ogata T, et al
  • Journal Title: Am J Med Genet A Volume: 158A(2) Pages: 465-8
  • Peer Reviewed
• [Journal Article] Prevalence and clinical features of Costello syndrome and cardio-facio-cutaneous syndrome in Japan (2012)
  • Author(s): Abe Y, Aoki Y, Ogata T, et al
  • Journal Title: Am J Med Genet A Volume: (accepted)(Epub ahead of print) Issue: 5 Pages: 1083-1094
  • DOI: 10.1002/ajmg.a.35292
  • Peer Reviewed
• [Journal Article] Two-step biochemical differential diagnosis of classical 21-hydroxylase deficiency and cytochrome P450 oxidoreductase deficiency in Japanese infants using uUrinary Pregnanetriolone/Tetrahydroxycortisone Ratio and 11β-hydroxyandrosterone by Gas chromatography-mass spectrometry (2012)
  • Author(s): Koyama Y, Ogata T, et al
  • Journal Title: Clin Chem Volume: 58(4) Pages: 741-7
  • Peer Reviewed
• [Journal Article] Screening of MAMLD1 mutations in 70 children with 46,XY DSD : Identification and functional analysis of 2 new mutations (2012)
  • Author(s): Kalfa N, Ogata T, et al
  • Journal Title: PLoS ONE Volume: 7(3)
  • Peer Reviewed
• [Journal Article] Identification, expression, and physiological functions of Siberian hamster gonadotropin-inhibitory hormone (2012)
  • Author(s): T.Ubuka, K.Tsutsui, et al
  • Journal Title: Endocrinology Volume: 153 Issue: 1 Pages: 373-385
  • DOI: 10.1210/en.2011-1110
  • Peer Reviewed
• [Journal Article] Acute stress increases the synthesis of 7α-hydroxypregnenolone, a new key neurosteroid stimulating locomotor activity, through corticosterone action (2012)
  • Author(s): S.Haraguchi, K.Tsutsui, et al
  • Journal Title: Endocrinology Volume: 153 Issue: 2 Pages: 794-805
  • DOI: 10.1210/en.2011-1422
  • Peer Reviewed
• [Journal Article] RNA interference of gonadotropin-inhibitory hormone gene induces arousal in songbirds (2012)
  • Author(s): T.Ubuka, K.Tsutsui, et al
  • Journal Title: PLoS ONE Volume: 7 Issue: 1 Pages: e30202-e30202
  • DOI: 10.1371/journal.pone.0030202
  • Peer Reviewed
• [Journal Article] Resveratrol promotes expression of SIRT1 and StAR in rat ovarian granulosa cells: class FormattedString { value: An implicative role of SIRT1 in the ovary } (2012)
  • Author(s): Y.Morita, K.Tsutsui, et al
  • Journal Title: Reprod.Biol.Endocrinbl. Volume: 10 Issue: 1 Pages: 14-24
  • DOI: 10.1186/1477-7827-10-14
  • URL: https://localhost/en/publications/a97f2630-e3b5-40c8-894e-fa987b90bada
  • Peer Reviewed
• [Journal Article] Mollusc gonadotropin-releasing hormone directly regulates gonadal functions : A primitive endocrine system controlling reproduction (2012)
  • Author(s): N.Treen, K.Tsutsui, et al
  • Journal Title: Gen.Comp.Endocrinol. Volume: (in press) Issue: 2 Pages: 167-172
  • DOI: 10.1016/j.ygcen.2012.01.008
  • Peer Reviewed
• [Journal Article] Hypothalamic gonadotropin-inhibitory hormone precursor mRNA is increased during depressed food intake in heat-exposed chicks (2012)
  • Author(s): V.S.Chowdhury, K.Tsutsui, et al
  • Journal Title: Comp.Biol.Physiol. Volume: (in press)
  • Peer Reviewed
• [Journal Article] Biological activity of novel lamprey RFamide peptides, specifically PQRFamide and their related peptides (2012)
  • Author(s): D.Daukss, K.Tsutsui, et al
  • Journal Title: Gen.Comp.Endocrinol. Volume: (in press)
  • Peer Reviewed
• [Journal Article] Gonadotropin-Inhibitory Hormone Inhibits Gonadotropin-Releasing Hormone-Induced Gonadotropin Synthesis Mediated by Adenylate Cyclase/cAMP/PKA-dependent ERK Pathway in LβT2 Gonadotrope Cells (2012)
  • Author(s): Y.L.Son, K.Tsutsui, et al
  • Journal Title: Endocrinology Volume: (in press)
  • Peer Reviewed
• [Journal Article] Evolutionary origin of the structure and function of gonadotropin-inhibitory hormone : Insights from lampreys (2012)
  • Author(s): T.Osugi, K.Tsutsui, et al
  • Journal Title: Endocrinology Volume: (in press)
  • Peer Reviewed
• [Journal Article] Regulation of neurosteroid biosynthesis by neurotransmitters and neuropeptides (2012)
  • Author(s): J.L.Do Rego, K.Tsutsui, et al
  • Journal Title: Front.Endocrin Volume: 3:article 4 Pages: 1-15
  • DOI: 10.3389/fendo.2012.00004
  • Peer Reviewed
• [Journal Article] 7α-Hydroxypregnenolone, a new key regulator of amphibian locomotion: discovery, progress and prospect (2012)
  • Author(s): Kazuyoshi Tsutsui
  • Journal Title: General and compaitive endocrinology Volume: 176 Issue: 3 Pages: 440-447
  • DOI: 10.1016/j.ygcen.2011.11.020
  • Peer Reviewed
• [Journal Article] Review : Control of circadian activity of birds by the interaction of melatonin with 7α-hydroxypregnenolone, a newly discovered neurosteroid stimulating locomotion (2012)
  • Author(s): K.Tsutsui, S.Haraguchi, et al
  • Journal Title: J.Ornitol. Volume: (in press) Issue: S1 Pages: 235-243
  • DOI: 10.1007/s10336-011-0795-x
  • Peer Reviewed
• [Journal Article] Neurosteroid biosynthesis and action during cerebellar development (2012)
  • Author(s): K.Tsutsui
  • Journal Title: Cerebellum Volume: (in press) Issue: 2 Pages: 414-415
  • DOI: 10.1007/s12311-011-0341-7
  • Peer Reviewed
• [Journal Article] Review : Gonadotropin-inhibitory hormone (GnIH) : discovery, progress and prospect (2012)
  • Author(s): K.Tsutsui, T.Ubuka, et al
  • Journal Title: Gen.Comp.Endocrinol. Volume: (in press)
  • Peer Reviewed
• [Journal Article] Identification and functional analysis of novel human growth hormone-releasing hormone receptor (GHRHR) gene mutations in Japanese subjects with short stature (2011)
  • Author(s): Inoue H, Ogata T, et al
  • Journal Title: Clin Endocrinol Volume: 74(2) Pages: 223-233
  • Peer Reviewed
• [Journal Article] Androgenetic/biparental mosaicism in a girl with Beckwith-Wiedemann syndrome-like and upd (14) pat-like phenotypes (2011)
  • Author(s): Yamazawa K, Ogata T, et al
  • Journal Title: J Hum Genet Volume: 56(1) Pages: 91-93
  • NAID: 10030657597
  • Peer Reviewed
• [Journal Article] Identification and functional analysis of novel human growth hormone secretagogue receptor (GHSR) gene mutations in Japanese subjects with short stature (2011)
  • Author(s): Inoue H, Ogata T, et al
  • Journal Title: J Clin Endocrinol Metab Volume: 96(2)
  • Peer Reviewed
• [Journal Article] GATA3 abnormalities in six patients with HDR syndrome (2011)
  • Author(s): Fukami M, Ogata T, et al
  • Journal Title: Endocr J Volume: 58(2) Pages: 117-121
  • NAID: 10029587700
  • Peer Reviewed
• [Journal Article] Identification of chromosome 15q terminal deletion with telomere sequences and its bearing on genotype-phenotype analysis (2011)
  • Author(s): Dateki S, Ogata T, et al
  • Journal Title: Endocr J Volume: 58(3) Pages: 155-159
  • Peer Reviewed
• [Journal Article] MAMLD1 (Mastermind-Like Domain Containing 1) Homozygous Gain-of-Function Missense Mutation Causing 46,XX Disorder of Sex Development in a Virilized Female (2011)
  • Author(s): Brandao MP, Ogata T, et al
  • Journal Title: Adv Exp Med Biol Volume: 707(10) Pages: 129-31
  • Peer Reviewed
• [Journal Article] Radiological evaluation of dysmorphic thorax in paternal uniparental disomy for chromosome 14 (2011)
  • Author(s): Miyazaki O, Ogata T, et al
  • Journal Title: Ped Radiol Volume: 41(8) Pages: 1013-1019
  • Peer Reviewed
• [Journal Article] Aromatase excess syndrome : identification of cryptic duplications and deletions leading to gain-of-function of CYP19A1 and assessment of phenotypic determinants (2011)
  • Author(s): Fukami, M, Ogata T, et al
  • Journal Title: J Clin Endocrinol Metab Volume: 96(6)
  • Peer Reviewed
• [Journal Article] Steroid 5α-reductase-2 deficiency and fertility (2011)
  • Author(s): Ogata T, Matsubara K
  • Journal Title: Fertil Steril Volume: 95(7)
  • Peer Reviewed
• [Journal Article] Mamldl knockdown reduces testosterone production and Cyp17al expression in mouse Leydig tumor cells (2011)
  • Author(s): Nakamura M, Ogata T, et al
  • Journal Title: PLoS ONE Volume: 6(4)
  • Peer Reviewed
• [Journal Article] Maternal age effect on the development of Prader-Willi syndrome resulting from upd (15) mat through meiosis 1 errors (2011)
  • Author(s): Matsubara K, Ogata T, et al
  • Journal Title: J Hum Genet Volume: 56(8) Pages: 566-71
  • NAID: 10030660380
  • Peer Reviewed
• [Journal Article] Methylation screening of reciprocal genome-wide UPDs identifies novel human specific imprinted genes (2011)
  • Author(s): Nakabayashi K, Ogata T, et al
  • Journal Title: Hum Mol Genet Volume: 20(16) Pages: 3188-97
  • Peer Reviewed
• [Journal Article] Analysis of expression and structure of the rat GH secretagogue/ghrelin receptor (Ghsr) gene : roles of epigenetic modifications in transcriptional regulation (2011)
  • Author(s): Inoue H, Ogata T, et al
  • Journal Title: Mol Cell Endocrinol Volume: 345 Pages: 1-15
  • Peer Reviewed
• [Journal Article] Proximal promoter of the cytochrome P450 oxidoreductase gene : identification of microdeletions involving the untranslated exon 1 and critical function of the SP1 binding site (2011)
  • Author(s): Soneda S, Ogata T, et al
  • Journal Title: J Clin Endocrinol Metab Volume: 96(11)
  • Peer Reviewed
• [Journal Article] Number of CGG repeats in the FMR1 gene of Japanese patients with primary ovanan insufficiency (2011)
  • Author(s): Ishizuka B, Ogata T, et al
  • Journal Title: Fertil Steril Volume: 96(5) Pages: 1170-1174
  • Peer Reviewed
• [Journal Article] Association of primary ovarian insufficiency with a specific HLA haplotype (A^*24:02-C^*03:03-B^*35:01) in Japanese patients (2011)
  • Author(s): Ayabe T, Ogata T, et al
  • Journal Title: Sex Dev Volume: 5(5) Pages: 235-240
  • Peer Reviewed
• [Journal Article] Polymorphisms of MAMLD1 gene in hypospadias (2011)
  • Author(s): Kalfa N, Ogata T, et al
  • Journal Title: J Pediatr Urol Volume: 7(6) Pages: 585-591
  • Peer Reviewed
• [Journal Article] Advanced maternal age and the development of Prader-Willi syndrome resulting from upd (15) mat through non-disjunction at meiosis 1 (2011)
  • Author(s): Ogata T, Matsubara K, et al
  • Journal Title: J Mamm Ova Res Volume: 28(3) Pages: 96-102
  • NAID: 10029898301
  • Peer Reviewed
• [Journal Article] Synchronised expressions of LPXRFamide peptide and its receptor genes : seasonal, diurnal and circadian changes during spawning period in grasspuffer (2011)
  • Author(s): M.Shahjahan, K.Tsutsui, et al
  • Journal Title: J.Endocrinol. Volume: 23 Issue: 1 Pages: 39-51
  • DOI: 10.1111/j.1365-2826.2010.02081.x
  • Peer Reviewed
• [Journal Article] Estrogen biosynthesis in the gonad of the frog Rana rugosa (2011)
  • Author(s): T.Isomura, K.Tsutsui, et al
  • Journal Title: Gen.Comp.Endocrinol. Volume: 170 Issue: 1 Pages: 207-212
  • DOI: 10.1016/j.ygcen.2010.10.015
  • Peer Reviewed
• [Journal Article] Expression of cytochrome P450 side-chain cleavage enzyme mRNA and production of pregnenolone in the brain of the red-bellied newt Cynops pyrrhogaster (2011)
  • Author(s): M.Takase, K.Tsutsui, et al
  • Journal Title: Gen.Comp.Endocrinol. Volume: 170 Issue: 3 Pages: 468-474
  • DOI: 10.1016/j.ygcen.2010.10.019
  • Peer Reviewed
• [Journal Article] Effects of gonadotropin-inhibitory hormone on folliculogenesis and steroidogenesis of cyclic mice (2011)
  • Author(s): P.Singh, K.Tsutsui, et al
  • Journal Title: Fertil.Steril. Volume: 95 Issue: 4 Pages: 1397-1404
  • DOI: 10.1016/j.fertnstert.2010.03.052
  • Peer Reviewed
• [Journal Article] Identification, localization and expression of LPXRFamide peptides, and melatonin-dependent induction of their precursor mRNA in the newt brain (2011)
  • Author(s): V.S.Chowdhury, K.Tsutsui, et al
  • Journal Title: J.Endocrinol. Volume: 209 Issue: 2 Pages: 1-12
  • DOI: 10.1530/joe-10-0494
  • Peer Reviewed
• [Journal Article] (*equalcontribution) Light-dependent and circadian clock-regulated activation of sterol regulatory element-binding protein, X-box-binding protein 1 and heat shock factor pathways (2011)
  • Author(s): Hatori,M.*, Hirota,T., Fukada,Y.
  • Journal Title: Proc. Natl. Acad. Sci. USA. Volume: 108 Issue: 12 Pages: 4864-4869
  • DOI: 10.1073/pnas.1015959108
  • Peer Reviewed
• [Journal Article] Identification, Localisation and Functional Implication of 26RFa Orthologue Peptide in the Brain of Zebra Finch (Taeniopygia guttata) (2011)
  • Author(s): Y.Tobari, K.Tsutsui, et al
  • Journal Title: J.Neuroendocrinol. Volume: 23 Issue: 9 Pages: 791
  • DOI: 10.1111/j.1365-2826.2011.02179.x
  • URL: https://pure.teikyo.jp/en/publications/70eda0c3-6213-4976-a722-9876ed8e2497
  • Peer Reviewed
• [Journal Article] Immunohistochemical localization of GnRH and RFamide-related peptide-3 during estrous cycle of mouse : Their potential role in the ovarian activity (2011)
  • Author(s): P.Singh, K.Tsutsui, et al
  • Journal Title: J.Mol.Histol. Volume: 42 Issue: 5 Pages: 371-81
  • DOI: 10.1007/s10735-011-9340-8
  • Peer Reviewed
• [Journal Article] Characterization of novel RFamide peptides in the central nervous system of the brown hagfish : isolation, localization, and functional analysis (2011)
  • Author(s): T.Osugi, K.Tsutsui, et al
  • Journal Title: Endocrinology Volume: 152 Pages: 4252-4264
  • Peer Reviewed
• [Journal Article] Hagfish, genome duplications, and RFamide neuropeptide evolution (2011)
  • Author(s): T.Osugi, K.Tsutsui, et al
  • Journal Title: Endocrinology Volume: 152 Issue: 11 Pages: 4010-4013
  • DOI: 10.1210/en.2011-1375
  • Peer Reviewed
• [Journal Article] Developmental changes in the mammalian gonadotropin-inhibitory hormone(GnIH) ortholog RFamide-related peptide(RFRP) and its cognate receptor GPR147 in the rat hypothalamus. (2011)
  • Author(s): Iwasa T, Matsuzaki T, Murakami M, Kinouchi R, Osugi T, Gereltsetseg G, Yoshida S, Irahara M, Tsutsui K.
  • Journal Title: Int J Dev Neurosci Volume: 30(1) Issue: 1 Pages: 31-37
  • DOI: 10.1016/j.ijdevneu.2011.10.003
  • Peer Reviewed
• [Journal Article] Mini-review : Molecular evolution and functional characterization of the orexigenic peptide 26RFa and its receptor in vertebrates : Discovery and comparative aspects (2011)
  • Author(s): K.Ukena, K.Tsutsui, et al
  • Journal Title: Cell Tissue Res Volume: 343 Issue: 3 Pages: 475-481
  • DOI: 10.1007/s00441-010-1116-z
  • Peer Reviewed
• [Journal Article] Historical view of development of comparative endocrinology in Japan (2011)
  • Author(s): Kikuyama S, Tsutsui K
  • Journal Title: Gen Comp Endocrinol Volume: 171 Issue: 2 Pages: 117-123
  • DOI: 10.1016/j.ygcen.2011.02.004
  • Peer Reviewed
• [Journal Article] Mode of action and functional significance of 7α-hydroxypregnenolone stimulating locomotor activity (2011)
  • Author(s): Shogo Haraguchi
  • Journal Title: Frontiers in Endocrinology Volume: 2 Pages: 1-8
  • DOI: 10.3389/fendo.2011.00023
  • Peer Reviewed
• [Journal Article] Review : Neurosteroid biosynthesis and function in the brain of domestic birds (2011)
  • Author(s): K.Tsutsui
  • Journal Title: Front.Endocrin. Volume: 2:article 37 Pages: 1-14
  • DOI: 10.3389/fendo.2011.00037
  • Peer Reviewed
• [Journal Article] Biosynthesis, mode of action and functional significance of neurosteroids in the Purkinje cell (2011)
  • Author(s): Kazuyoshi Tsutsui
  • Journal Title: Frontiers in Endocrinology Volume: 2 Pages: 1-9
  • DOI: 10.3389/fendo.2011.00061
  • Peer Reviewed
• [Journal Article] Review : Neurosteroid biosynthesis in the brain of amphibians (2011)
  • Author(s): H.Vaudry, K.Tsutsui, et al
  • Journal Title: Front.Endocrin Volume: 2:article 79 Pages: 1-9
  • DOI: 10.3389/fendo.2011.00079
  • Peer Reviewed
• [Journal Article] Estradiol promotes Purkinje dendritic growth, spinogenesis and synaptogenesis during neonatal life by inducing the expression of BDNF (2011)
  • Author(s): Shogo Haraguchi
  • Journal Title: The Cerebellum Volume: (in press) Issue: 2 Pages: 416-417
  • DOI: 10.1007/s12311-011-0342-6
  • Peer Reviewed
• [Journal Article] Light-dependent and circadian clock-regulated activation of SREBP, XBP1 and HSF pathways (2011)
  • Author(s): M.Hatori, T.K.Tsutsui, 他
  • Journal Title: Proc.Natl.Acad.Sci.USA Volume: 108 Pages: 4864-4869
  • Peer Reviewed
• [Journal Article] Synchronised expressions of LPXRFamide peptide and its receptor genes : seasonal, diurnal and circadian changes during spawning period in grass puffer (2011)
  • Author(s): M.Shahjahan, K.Tsutsui, 他
  • Journal Title: J.Neuroendocrinol. Volume: 23 Pages: 39-51
  • Peer Reviewed
• [Journal Article] Historical view of development of comparative endocrinology in Japan (2011)
  • Author(s): S.Kikuyama, K.Tsutsui
  • Journal Title: Gen.Comp.Endocrinol. Volume: 171 Pages: 117-123
  • Peer Reviewed
• [Journal Article] GnIHの発見とGnIH研究の進展・展望-鳥類から哺乳類、ヒトへの展開 (2011)
  • Author(s): 筒井和義
  • Journal Title: 比較内分泌学 Volume: 37 Pages: 21-28
  • NAID: 10027947486
  • Peer Reviewed
• [Journal Article] Heterozygous OTX2 mutations are associated with variable pituitary phenotype (2010)
  • Author(s): Dateki S, Fukami M, Ogata T, 他
  • Journal Title: J Clin Endocrinol Metab Volume: 95(2) Pages: 756-764
  • Peer Reviewed
• [Journal Article] Hypothalamic dysfunction in a female with isolated hypogonadotropic hypogonadism and compound heterozygous TACR3 mutations and clinical manifestation in her heterozygous mother (2010)
  • Author(s): Fukami M, Ogata T, 他
  • Journal Title: Horm Res Peadiatr Volume: 73(6) Pages: 477-481
  • Peer Reviewed
• [Journal Article] Mutation and gene copy number analyses of six pituitary transcription factor genes in 71 patients with combined pituitary hormone deficiency : identification of a single patient with LHX4 deletion (2010)
  • Author(s): Dateki S, Fukami M, Ogata T, 他
  • Journal Title: J Clin Endocrinol Metab Volume: 95(8) Pages: 4043-4047
  • Peer Reviewed
• [Journal Article] Anorectal and urinary anomalies and aberrant retinoic acid metabolism in cytochrome P450 oxidoreductase deficiency (2010)
  • Author(s): Fukami M, Nagai T, Mochizuki H, Muroya K, Yamada G, Takitani K, Ogata T
  • Journal Title: Mol Genet Metab Volume: 100(3) Pages: 269-273
  • Peer Reviewed
• [Journal Article] A novel loss of function mutation in OTX2 is associated with phenotypically variable anophthalmia and isolated growth hormone deficiency (2010)
  • Author(s): Ashkenazi-Hoffnung L, Ogata T, 他
  • Journal Title: Hum Genet Volume: 127(6) Pages: 721-729
  • Peer Reviewed
• [Journal Article] Semen analysis and successful paternity by intracytoplasmic sperm injection in a man with steroid 5α-reductase-2 deficiency (2010)
  • Author(s): Matsubara K, Iwamoto H, Yoshida A, Ogata T
  • Journal Title: Fertil Steril Volume: 94(7)
  • Peer Reviewed
• [Journal Article] Identification of chromosome 15q terminal deletion with telomere sequences and its bearing on genotype-phenotype analysis (2010)
  • Author(s): Dateki S, Fukami M, Ogata T, 他
  • Journal Title: Endocr J Volume: (accepted)
  • Peer Reviewed
• [Journal Article] Exonic polymorphisms of MAMLD1 (CXorf6) are associated with hypospadias (2010)
  • Author(s): Kalfa N, Fukami M, Ogata T, 他
  • Journal Title: J Urol Volume: (accepted)
  • Peer Reviewed
• [Journal Article] Aromatase excess syndrome : identification of cryptic duplications and deletions leading to gain-of-function of CYP19A1 and assessment of phenotypic determinants (2010)
  • Author(s): Fukami M, Ogata T, 他
  • Journal Title: J Clin Endocrinol Metab Volume: (accepted)
  • Peer Reviewed
• [Journal Article] 中枢性性腺機能低下症 (2010)
  • Author(s): 深見真紀, 伊達木澄人, 緒方勤
  • Journal Title: Horm Front Gynecol Volume: 17(2) Pages: 4-8
• [Journal Article] Prokineticin signaling pathwayとKallmann症候群 (2010)
  • Author(s): 佐藤直子, 緒方勤
  • Journal Title: 医のあゆみ Volume: 233(9) Pages: 934-938
  • Peer Reviewed
• [Journal Article] Age-dependent variation in the RFRP-3 neurons is inversely correlated with gonadal activity of mice (2010)
  • Author(s): S.Sethi, K.Tsutsui, C.M.Chaturvedi
  • Journal Title: Gen.Comp.Endocrinol. Volume: 168 Pages: 326-332
  • Peer Reviewed
• [Journal Article] Photoperiod and reproductive condition are associated with changes in RFamide-related peptide (RFRP) expression in Syrian hamsters (Mesocricetus auratus) (2010)
  • Author(s): A.O.Mason, K.Tsutsui, 他
  • Journal Title: J.Biol.Rhythm. Volume: 25 Pages: 176-85
  • Peer Reviewed
• [Journal Article] Identification, localization and function of a novel avian hypothalamic neuropeptide, 26RFa, and its cognate receptor, GPR103 (2010)
  • Author(s): K.Ukena, K.Tsutsui, 他
  • Journal Title: Endocrinology Volume: 151 Pages: 2255-2264
  • Peer Reviewed
• [Journal Article] Prolactin increases the synthesis of 7□-hydroxypregnenolone, a key factor for induction of locomotor activity, in breeding male newts (2010)
  • Author(s): S.Haraguchi, K.Tsutsui, 他
  • Journal Title: Endocrinology Volume: 151 Pages: 2211-2222
  • Peer Reviewed
• [Journal Article] Identification of gonadotropin-inhibitory hormone in the zebra finch(Taeniopygia guttata) : peptide isolation, cDNA cloning and brain distribution (2010)
  • Author(s): Y.Tobari, N.K.Tsutsui, 他
  • Journal Title: Peptides Volume: 31 Pages: 816-826
  • Peer Reviewed
• [Journal Article] Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6 (2010)
  • Author(s): M.Doi, K.Tsutsui, 他
  • Journal Title: Nature Medicine Volume: 16 Pages: 67-74
  • Peer Reviewed
• [Journal Article] RFamide-related peptide (RFRP) and mRNA expression in mammaliantestis : Association with the spermatogenic cycle (2010)
  • Author(s): S.Zhao, K.Tsutsui, 他
  • Journal Title: Endocrinology Volume: 151 Pages: 617-627
  • Peer Reviewed
• [Journal Article] Melatonin stimulates the release of gonadotropin-inhibitory hormone by the avian hypothalamus (2010)
  • Author(s): V.S.Chowdhury, K.Tsutsui, 他
  • Journal Title: Endocrinology Volume: 151 Pages: 271-280
  • Peer Reviewed
• [Journal Article] Temporal phase relation of circadian neural oscillations alters RFamide-related peptide-3 (RFRP-3), a mammalian gonadotropin-inhibitory hormone (GnIH) homolog, and testicular function in the mouse (Mus musculus) (2010)
  • Author(s): S.Sethi, K.Tsutsui, C.M.Chaturvedi
  • Journal Title: Neuroendocrinology Volume: 91 Pages: 189-199
  • Peer Reviewed
• [Journal Article] Molecular evolution and functional characterization of the orexigenic peptide 26RFa and its receptor in vertebrates : Discovery and comparative aspects (2010)
  • Author(s): K.Ukena, H.Vaudry, J.Leprince, K.Tsutsui
  • Journal Title: Cell Tissue Res. Volume: 343 Pages: 475-481
  • Peer Reviewed
• [Journal Article] 7□-Hydroxypregnenolone, a new key regulator of locomotor activity of vertebrates : Identification, mode of action and functional significance (2010)
  • Author(s): K.Tsutsui, 他
  • Journal Title: Front.Endocrin. Volume: 1 Pages: 1-13
  • Peer Reviewed
• [Journal Article] Recent studies of Gonadotropin-Inhibitory Hormone (GnIH) in the mammalian hypothalamus, pituitary and gonads (2010)
  • Author(s): G.E.Bentley, K.Tsutsui, L.J.Kriegsfeld
  • Journal Title: Brain Res. Volume: 1364 Pages: 62-71
  • Peer Reviewed
• [Journal Article] Identification of 7□-hydroxypregnenolone, a novel bioactive amphibian neurosteroid stimulating locomotor activity, and its physiological roles in the regulation of locomotion (2010)
  • Author(s): K.Tsutsui, 他
  • Journal Title: Gen.Comp.Endocrinol. Volume: 168 Pages: 275-279
  • Peer Reviewed
• [Journal Article] Discovery and Evolutionary History of GnIH and Kisspeptin : New Key Neuropeptides Controlling Reproduction (2010)
  • Author(s): K.Tsutsui, 他
  • Journal Title: J.Neuroendocrinol Volume: 22 Pages: 716-727
  • Peer Reviewed
• [Journal Article] The roles of RFamide-related peptide-3 (RFRP-3) in mammalian reproductive function and behaviour (2010)
  • Author(s): L.J.Kriegsfeld, K.Tsutsui, 他
  • Journal Title: J.Neuroendocrinol Volume: 22 Pages: 692-700
  • Peer Reviewed
• [Journal Article] Gonadotropin-inhibitory hormone (GnIH) and its control of central and peripheral reproductive function (2010)
  • Author(s): K.Tsutsui, 他
  • Journal Title: Front.Neuroendocrinol. Volume: 31 Pages: 284-295
  • Peer Reviewed
• [Journal Article] Phylogenetic aspects of gonadotropin-inhibitory hormone (GnIH)and its homologs in vertebrates (2010)
  • Author(s): K.Tsutsui
  • Journal Title: Ann.N.Y.Acad.Sci. Volume: 1200 Pages: 75-84
  • Peer Reviewed
• [Journal Article] 性周期とニューロペプチド (2010)
  • Author(s): 筒井和義・産賀崇由
  • Journal Title: Hormone Frontier in Gynecology Volume: 17 Pages: 25-29
  • Peer Reviewed
• [Journal Article] GnIHによるゴナドトロピン分泌制御.特集/生殖機能調節の新しい視点 (2010)
  • Author(s): 筒井和義
  • Journal Title: 産科と婦人科 Volume: 77 Pages: 252-258
  • NAID: 40017005894
  • Peer Reviewed
• [Journal Article] Association between fetal myocardial tissue Doppler indices before birth and gestational age-specific birth weight in low-risk term pregnancies
  • Author(s): Sekii K, Ogata T, et al
  • Journal Title: Ultrasound Obstet Gynecol Volume: (accepted)(Epub ahead of print)
  • Peer Reviewed
• [Journal Article] Complex genomic rearrangements in the SOX9 5' region in a patient with Pierre Robin sequence and hypoplastic left scapula
  • Author(s): Fukami M, Ogata T, et al
  • Journal Title: Am J Med Genet A Volume: (accepted)
  • Peer Reviewed
• [Journal Article] Haplotype analysis of ESR2 in Japanese patients with spermatogenic failure : Implications for genetic susceptibility to estrogenic environmental endocrine disruptors
  • Author(s): Ogata T, Fukami M, et al
  • Journal Title: Int J Androl Volume: (accepted)
  • Peer Reviewed
• [Journal Article] Molecular bases and phenotypic determinants of aromatase excess syndrome
  • Author(s): Fukami M, Shozu M, Ogata T
  • Journal Title: Int J Endocrinol Volume: (accepted)
  • Peer Reviewed
• [Journal Article] MAMLD1 and 46,XY disorders of sex development
  • Author(s): Ogata T, Sano S, et al
  • Journal Title: Seminars in Reproductive Medicine Volume: (accepted)
  • Peer Reviewed
• [Presentation] 性分化疾患における性同一性障害：性差構築からみる性同一性障害の治療戦略 (2015)
  • Author(s): 緒方勤
  • Organizer: GID（性同一性障害）学会 第17回研究大会
  • Place of Presentation: 大阪
  • Year and Date: 2015-03-21 – 2015-03-22
  • Invited
• [Presentation] Environmental Impacts on Male Sexual Differentiation. (2014)
  • Author(s): Ogata T
  • Organizer: 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo
  • Place of Presentation: シカゴ（米国）
  • Year and Date: 2014-06-21 – 2014-06-24
  • Invited
• [Presentation] 精子形成障害と内分泌撹乱化学物質感受性． (2014)
  • Author(s): 緒方勤
  • Organizer: 第33回アンドロロジー学会
  • Place of Presentation: 軽井沢
  • Year and Date: 2014-06-12 – 2014-06-13
  • Invited
• [Presentation] わかりやすい臨床遺伝学 (2014)
  • Author(s): 緒方勤
  • Organizer: 第9回日本小児耳鼻咽喉科学会
  • Place of Presentation: 浜松
  • Year and Date: 2014-06-06 – 2014-06-07
  • Invited
• [Presentation] インプリンティング疾患発症機序について (2014)
  • Author(s): 緒方勤
  • Organizer: 第56回日本小児神経学会
  • Place of Presentation: 浜松
  • Year and Date: 2014-05-29 – 2014-05-31
  • Invited
• [Presentation] Genetics of DSD (Disorders of sex development) (2014)
  • Author(s): Ogata T
  • Organizer: PAS/ASPR (Pediatric Academic Societies and Asian Society for Pediatric Research) 2014.
  • Place of Presentation: バンクーバー（カナダ）
  • Year and Date: 2014-05-03 – 2014-05-06
  • Invited
• [Presentation] インプリンティング機構と胎児・胎盤の成長 (2014)
  • Author(s): 緒方勤
  • Organizer: 第87回日本内分泌学会
  • Place of Presentation: 福岡
  • Year and Date: 2014-04-24 – 2014-04-26
  • Invited
• [Presentation] 四肢形成不全の分子遺伝学：裂手裂足症およびその関連疾患の発症機序 2014年4月17–18日，那覇． (2014)
  • Author(s): 緒方勤
  • Organizer: 第57回日本手外科学会学術集会
  • Place of Presentation: 那覇
  • Year and Date: 2014-04-17 – 2014-04-18
  • Invited
• [Presentation] 内分泌撹乱環境化学物質と男児外性器異常 (2014)
  • Author(s): 緒方勤
  • Organizer: 第117回日本小児科学会学術集会
  • Place of Presentation: 名古屋
  • Year and Date: 2014-04-11 – 2014-04-13
  • Invited
• [Presentation] Progress in comparative endocrinology by discovering novel neuropeptides and neurosteroids (2014)
  • Author(s): K. Tsutsui
  • Organizer: The 7th Intercongress symposium of the Asia and Oceania Society for the Comparative Endocrinology (AOSCE)
  • Place of Presentation: National Taiwan Ocean University, Keelung, Taiwan
  • Invited
• [Presentation] ineal allopregnanolone saves purkinje cells from apoptosis in the cerebellum. (2014)
  • Author(s): S. Haraguchi, S. Hara, T. Ubuka, K. Tsutsui
  • Organizer: The 7th Intercongress symposium of the AOSCE
  • Place of Presentation: National Taiwan Ocean University, Keelung, Taiwan
  • Invited
• [Presentation] Transcriptional activation of gonadotropin-inhibitory hormone by corticosterone (2014)
  • Author(s): Y. L. Son, T. Ubuka, M. Narihiro, Y. Fukuda, I. Hasunuma, K. Yamamoto, D. D. Belsham, K. Tsutsui
  • Organizer: The 7th Intercongress symposium of the AOSCE
  • Place of Presentation: National Taiwan Ocean University, Keelung, Taiwan
  • Invited
• [Presentation] Genetics of Combined Pituitary Hormone Deficiency. In: Symposium, Neuroendocrinology, Novel Players in Pituitary Disorders. 2013 Seoul International Congress of Endocrinology and Metabolism; (2013)
  • Author(s): Ogata T
  • Organizer: In conjunction with the 32nd Annual Meeting of the Korean Endocrine Society
  • Place of Presentation: Seoul, South Korea
  • Invited
• [Presentation] Genetic advances in DSD (2013)
  • Author(s): Ogata T
  • Organizer: The Joint Summer School for Pediatric Endocrinology.
  • Place of Presentation: Lake Maggiore, Italy
  • Invited
• [Presentation] 脳の性分化に関する最近の知見 (2013)
  • Author(s): 緒方勤
  • Organizer: 第22回日本小児泌尿器科学会教育講演
  • Place of Presentation: 東京ビックサイトTFTホール（東京都江東区）
  • Invited
• [Presentation] 性分化疾患の発症機序：最新の知見 (2013)
  • Author(s): 緒方勤
  • Organizer: 日本アンドロロジー学会第32回学術大会・第19回精子形成・精巣毒性研究会共同開催学会特別講演
  • Place of Presentation: グランキューブ大阪（大阪府大阪市）
  • Invited
• [Presentation] 生殖補助医療と小児医療の接点 (2013)
  • Author(s): 緒方勤
  • Organizer: オーバービュー．第116回日本小児科学会学術集会：生殖補助医療と小児医療の接点
  • Place of Presentation: 広島
  • Invited
• [Presentation] 先天性副腎ステロイド合成異常症 (2013)
  • Author(s): 緒方勤
  • Organizer: シンポジウム：ステロイドホルモン研究Update．第86回日本内分泌学会学術集会．
  • Place of Presentation: 仙台
  • Invited
• [Presentation] インプリンティング疾患の遺伝子診断 (2013)
  • Author(s): 緒方勤
  • Organizer: 第14染色体父性ダイソミー表現型をモデルとして．シンポジウム：単因子疾患の遺伝子診療．第20回日本遺伝子診療学会
  • Place of Presentation: 浜松
  • Invited
• [Presentation] 生殖補助医療とインプリンティング疾患発症 (2013)
  • Author(s): 緒方勤
  • Organizer: シンポジウム：疾患から見たARTとエピゲノム．第31回日本受精着床学会学術集会
  • Place of Presentation: 別府
  • Invited
• [Presentation] Gonadotropin-inhibitory hormone (GnIH), a new key neurohormone regulating reproduction: Discovery, progress and perspective (2013)
  • Author(s): K. Tsutsui
  • Organizer: The International Conference on Comparative Endocrinology and Physiology (ICCEP-2013)
  • Place of Presentation: RTM Nagpur University, Nagpur, India
  • Invited
• [Presentation] Breakthrough in neuroendocrinology by discovering novel neuropeptides and neurosteroids (特別講演: Bargmann-Scharrer Lecture) (2013)
  • Author(s): K. Tsutsui
  • Organizer: The 17th International Congress of Comparative Endocrinology (ICCE),
  • Place of Presentation: University of Barcelona, Barcelona, Spain
  • Invited
• [Presentation] Pineal allopregnanolone saves cerebellar Purkinje cells from apoptosis (2013)
  • Author(s): S. Haraguchi, S. Hara, T. Ubuka, M. Mita, K. Tsutsui
  • Organizer: The 17th ICCE
  • Place of Presentation: University of Barcelona, Barcelona, Spain
• [Presentation] Female presence increases gonadotropin-inhibitory hormone gene expression by decreasing norepinephrine in the male quail brain (招待講演) (2013)
  • Author(s): Y. Tobari, Y. L. Son, Y. Hasegawa, K. Tsutsui
  • Organizer: The 17th ICCE
  • Place of Presentation: University of Barcelona, Barcelona, Spain
  • Invited
• [Presentation] Gonadotropin-inhibitory hormone inhibits AC/cAMP/PKA-mediated signaling pathway in gonadotropes and GnRH neurons (2013)
  • Author(s): Y. L. Son, T. Ubuka, R. P. Millar, K. Tsutsui
  • Organizer: The 17th ICCE
  • Place of Presentation: University of Barcelona, Barcelona, Spain
• [Presentation] Gonadotropin-inhibitory hormone inhibits aggressive behavior by increasing estrogen synthesis in the brain beyond its optimum concentration (2013)
  • Author(s): T. Ubuka, S. Haraguchi, N. Harada, K. Tsutsui
  • Organizer: The 17th ICCE
  • Place of Presentation: University of Barcelona, Barcelona, Spain
• [Presentation] 生殖を抑制する新規脳ホルモンの発見と研究進展：鳥類から哺乳類への展開 (2013)
  • Author(s): 筒井和義
  • Organizer: 第2回実験動物科学シンポジウム－新たなライフサイエンス研究の展開－鳥類リソースの整備と活用に向けて
  • Place of Presentation: 名古屋大学野依記念学術交流館（名古屋市千種区）
  • Invited
• [Presentation] The signaling pathway mediating the inhibitory effect of gonadotropin-inhibitory hormone (GnIH) in gonadotropes and GnRH neurons (2013)
  • Author(s): Y. L. Son, T. Ubuka, K. Tsutsui
  • Organizer: 第18回日本生殖内分泌学会学術集会
  • Place of Presentation: シェーンバッハ・サボー（東京都千代田区）
• [Presentation] Biosynthesis and biological action of pineal neurosteroids in birds (2013)
  • Author(s): K. Tsutsui, S. Haraguch
  • Organizer: 第37回鳥類内分泌研究会
  • Place of Presentation: アソシエート（熊本県阿蘇郡）
• [Presentation] Neuroendocrine mechanisms translating social stimuli into reproductive physiology and behavior (2013)
  • Author(s): Y. Tobari, Y. L. Son, T. Ubuka, Y. Hasegawa, K. Tsutsui
  • Organizer: 第37回鳥類内分泌研究会
  • Place of Presentation: アソシエート（熊本県阿蘇郡）
• [Presentation] 視床下部ホルモンの比較内分泌学 (2013)
  • Author(s): 筒井和義
  • Organizer: 第38回日本比較内分泌学会大会・小林英司先生記念シンポジウム
  • Place of Presentation: 宮崎市民プラザ（宮崎県宮崎市）
  • Invited
• [Presentation] サケの遡上行動を促進する7alpha-ヒドロキシプレグネノロンの作用機構 (2013)
  • Author(s): 鈴木悠子、原口省吾、山本雄三、張雋螢、小山鉄平、三田雅敏、上田宏、筒井和義
  • Organizer: 第38回日本比較内分泌学会大会・小林英司先生記念シンポジウム
  • Place of Presentation: 宮崎市民プラザ（宮崎県宮崎市）
• [Presentation] 精巣由来アンドロゲンによる脳内7alpha-ヒドロキシプレグネノロン合成制御 (2013)
  • Author(s): 原口省吾、鈴木悠子、田代渓一郎、三田雅敏、筒井和義
  • Organizer: 第38回日本比較内分泌学会大会・小林英司先生記念シンポジウム
  • Place of Presentation: 宮崎市民プラザ（宮崎県宮崎市）
• [Presentation] サケの遡上行動を促進する7alpha-ヒドロキシプレグネノロンの作用機構 (2013)
  • Author(s): 鈴木悠子、原口省吾、山本雄三、張雋螢、小山鉄平、三田雅敏、上田宏、筒井和義
  • Organizer: 第84回日本動物学会大会
  • Place of Presentation: 岡山大学津島キャンパス（岡山県岡山市）
• [Presentation] 松果体で合成されたアロプレグナノロンは小脳プルキンエ細胞の細胞死を防ぐ (2013)
  • Author(s): 原口省吾、原桜子、産賀崇由、三田雅敏、筒井和義
  • Organizer: 第84回日本動物学会大会
  • Place of Presentation: 岡山大学津島キャンパス（岡山県岡山市）
• [Presentation] GnIHによるGnRHニューロン内シグナリング抑制機構 (2013)
  • Author(s): 孫ユリ、産賀崇由、筒井和義
  • Organizer: 第84回日本動物学会大会
  • Place of Presentation: 岡山大学津島キャンパス（岡山県岡山市）
• [Presentation] GnIH はニューロエストロゲン合成を促進して攻撃行動を抑制する (2013)
  • Author(s): 産賀崇由、原口省吾、原田信弘、筒井和義
  • Organizer: 第84回日本動物学会大会
  • Place of Presentation: 岡山大学津島キャンパス（岡山県岡山市）
• [Presentation] 生殖生理と生殖行動を変化させる社会的刺激の脳内機構 (2013)
  • Author(s): 戸張靖子、孫ユリ、産賀崇由、長谷川喜久、筒井和義
  • Organizer: 第84回日本動物学会大会
  • Place of Presentation: 岡山大学津島キャンパス（岡山県岡山市）
• [Presentation] Kiss2の分子進化に関する研究 (2013)
  • Author(s): 大杉知裕、大滝直仁、砂川裕哉、孫ユリ、大久保誠、飯郷雅之、天野勝文、筒井和義
  • Organizer: 第84回日本動物学会大会
  • Place of Presentation: 岡山大学津島キャンパス（岡山県岡山市）
• [Presentation] GnIHによる視床下部P450arom活性の制御と性差 (2013)
  • Author(s): 産賀崇由、筒井和義
  • Organizer: 新学術領域研究「性差構築の分子基盤」第5回領域会議
  • Place of Presentation: 国民宿舎虹の松原ホテル（佐賀県唐津市）
• [Presentation] 視床下部ホルモンの発見と比較内分泌学の進展 (2013)
  • Author(s): 筒井和義
  • Organizer: 東京大学大気海洋研究所共同利用研究集会－海洋生物のさまざまな適応戦略
  • Place of Presentation: 東京大学大気海洋研究所（千葉県柏市）
  • Invited
• [Presentation] 脳におけるprogesteroneとallopregnanoloneの生合成と生理作用 (2013)
  • Author(s): 筒井和義
  • Organizer: 第2回プロゲストーゲン研究会
  • Place of Presentation: 第一ホテル東京（東京都港区）
  • Invited
• [Presentation] バックドア経路：テストステロンを経由しないジヒドロテストステロン産生経路 (2012)
  • Author(s): 緒方勤
  • Organizer: 第35回日本分子生物学会学術集会ワークショップ 哺乳類の性分化・性成熟の新知見 性腺機能を制御する遺伝子ネットワークとその破綻による疾患
  • Place of Presentation: 福岡
  • Year and Date: 2012-12-11
  • Invited
• [Presentation] Aromatase Excess Syndrome as a Model for Genomic Disorder: Identification of Molecular Bases and Phenotypic Determinants. (2012)
  • Author(s): Ogata T, Shozu M, Fukami M
  • Organizer: Kaichi Kida Session. The 7th Asia Pacific Paediatric Endocrine Society Meeting.
  • Place of Presentation: Bali, Indonesia.
  • Year and Date: 2012-11-14
  • Invited
• [Presentation] Genetics of DSD (Disorders of sex development). (2012)
  • Author(s): Ogata T
  • Organizer: Disorders of sex development. The 15th International and 14th European Congress of Endocrinology (ICE/ECE).
  • Place of Presentation: Florence, Italy.
  • Year and Date: 2012-05-05
  • Invited
• [Presentation] Cytochrome P450 Oxidoreductase Deficiency: A Unique Disease Leading to Disorders of Sex Development in Both 46,XY and 46,XX Patients. Invited Lecture. (2012)
  • Author(s): Ogata T
  • Organizer: The 6th International Symposium on the Biology of Vertebrate Sex Determination.
  • Place of Presentation: Kona Hawaii, USA.
  • Year and Date: 2012-04-23
  • Invited
• [Presentation] 胎児期における環境化学物質と先天奇形の発症 (2012)
  • Author(s): 緒方勤
  • Organizer: 第115回日本小児科学会学術集会：子どもの健康と環境に関する全国調査（エコチル調査）と小児内分泌代謝疾患
  • Place of Presentation: 福岡
  • Year and Date: 2012-04-20
  • Invited
• [Presentation] 性の分化・発達と小児医療 (2012)
  • Author(s): 緒方勤
  • Organizer: 第188回浜松市小児科医会研究会
  • Place of Presentation: 浜松
  • Year and Date: 2012-03-07
• [Presentation] Mollusc gonadotropin-releasing hormone directly regulates gonadal functions : A primitive endocrine system controlling reproduction (2012)
  • Author(s): N.Treen, K.Tsutsui, et al
  • Organizer: The 7th Congress of the Asia and Oceania Society for Comparative Endocrinology
  • Place of Presentation: Sunway Resort Hotel, Kuala Lumpur, Malaysia
  • Year and Date: 2012-03-05
• [Presentation] Evolutionary origin of the structure and function of gonadotropin-inhibitory hormone (GnIH) (2012)
  • Author(s): T.Osugi, K.Tsutsui, et al
  • Organizer: The 7th Congress of the Asia and Oceania Society for Comparative Endocrinology
  • Place of Presentation: Sunway Resort Hotel, Kuala Lumpur, Malaysia
  • Year and Date: 2012-03-05
• [Presentation] Acute stress increases the synthesis of 7alpha-hydroxypregnenolone, a new key neurosteroid stimulating locomotor activity, through corticosteroneaction (2012)
  • Author(s): S.Haraguchi, K.Tsutsui, et al
  • Organizer: The 7th Congress of the Asia and Oceania Society for Comparative Endocrinology
  • Place of Presentation: Sunway Resort Hotel, Kuala Lumpur, Malaysia
  • Year and Date: 2012-03-05
• [Presentation] Identification and distribution of gonadotropin-inhibitory hormone (GnIH) in the brain of Zebra finch (2012)
  • Author(s): Y.Tobari, K.Tsutsui, et al
  • Organizer: The 7th Congress of the Asia and Oceania Society for Comparative Endocrinology
  • Place of Presentation: Sunway Resort Hotel, Kuala Lumpur, Malaysia
  • Year and Date: 2012-03-05
• [Presentation] 性分化疾患の基礎と臨床 (2012)
  • Author(s): 緒方勤
  • Organizer: 第58回愛媛県小児科医会特別講演
  • Place of Presentation: 松山
  • Invited
• [Presentation] 性分化疾患とゲノム異常 (2012)
  • Author(s): 緒方勤
  • Organizer: 第15回宮崎代謝内分泌研究会
  • Place of Presentation: 宮崎
  • Invited
• [Presentation] 環境ホルモン物質の子どもへの影響 (2012)
  • Author(s): 緒方勤
  • Organizer: 松葉のダイオキシン調査実行委員会研修会
  • Place of Presentation: 東京
  • Invited
• [Presentation] Create new research directions in comparative endocrinology from Asia and Oceania (2012)
  • Author(s): K.Tsutsui
  • Organizer: The 7th Congress of the Asia and Oceania Society for Comparative Endocrinology
  • Place of Presentation: Sunway Resort Hotel, Kuala Lumpur, Malaysia
• [Presentation] Melatonin stimulates the synthes's and release of gonadotropin-inhibitory hormone in birds (2012)
  • Author(s): V.S.Chowdhury, T.Ubuka, K.Tsutsui
  • Organizer: The 7th Congress of the Asia and Oceania Society for Comparative Endocrinology
  • Place of Presentation: Sunway Resort Hotel, Kuala Lumpur, Malaysia
• [Presentation] RNA interference of gonadotropin-inhibitory hormone gene induces aggressive and sexual behaviors in birds (2012)
  • Author(s): T.Ubuka, K.Tsutsui
  • Organizer: The 7th Congress of the Asia and Oceania Society for Comparative Endocrinology
  • Place of Presentation: Sunway Resort Hotel, Kuala Lumpur, Malaysia
• [Presentation] 「システム生命科学による医・理・工学の先端研究」生体機能を調節する脳ホルモンの発見と理解の到達点 (2011)
  • Author(s): 筒井和義
  • Organizer: ハイテクジョイントシンポジウム
  • Place of Presentation: 早稲田大学理工学部50号館・東京
  • Year and Date: 2011-12-10
• [Presentation] ターナー症候群を招く分子基盤 (2011)
  • Author(s): 緒方勤
  • Organizer: 第7回北関東遺伝診療フォーラム
  • Place of Presentation: 大宮
  • Year and Date: 2011-12-09
• [Presentation] キンカチョウの脳における生殖線刺激ホルモン放出抑制ホルモン(GnIH)の同定と脳内分布 (2011)
  • Author(s): 戸張靖子、筒井和義, 他
  • Organizer: 第36回日本比較内分泌学会大会
  • Place of Presentation: 都道府県会館・東京
  • Year and Date: 2011-11-24
• [Presentation] ハムスターの生殖腺刺激ホルモン放出抑制ホルモン(GnIH)の同定、発現制御および生理作用 (2011)
  • Author(s): 産賀崇由、筒井和義, 他
  • Organizer: 第36回日本比較内分泌学会大会
  • Place of Presentation: 都道府県会館・東京
  • Year and Date: 2011-11-24
• [Presentation] ウシガエルの脳におけるneuropeptide FF cDNAのクローニングと内因性リガンドの同定 (2011)
  • Author(s): 大杉知裕、筒井和義, 他
  • Organizer: 第36回日本比較内分泌学会大会
  • Place of Presentation: 都道府県会館・東京
  • Year and Date: 2011-11-24
• [Presentation] メダカ脳におけるgonadotropin-inhibitory hormone (GnIH) cDNAのクローニング (2011)
  • Author(s): 岡村友貴、筒井和義, 他
  • Organizer: 第36回日本比較内分泌学会大会
  • Place of Presentation: 都道府県会館・東京
  • Year and Date: 2011-11-24
• [Presentation] The mammalian GnIH ortholog RFRP inhibits gonadotropin gene expression by inhibiting AC/cAMP/PKA-mediated ERK activation (2011)
  • Author(s): Kazuyoshi Tsutsui, et al
  • Organizer: 第36回日本比較内分泌学会大会
  • Place of Presentation: 都道府県会館・東京
  • Year and Date: 2011-11-24
• [Presentation] ストレスが誘導する脳内7alpha-ヒドロキシプレグネノロン合成の変動とその制御機構 (2011)
  • Author(s): 原口省吾、筒井和義, 他
  • Organizer: 第36回日本比較内分泌学会大会
  • Place of Presentation: 都道府県会館・東京
  • Year and Date: 2011-11-24
• [Presentation] 遡上中のサケの脳内では7alpha-ヒドロキシプレグネノロンの合成が高まる (2011)
  • Author(s): チャンジュンヒョン、筒井和義, 他
  • Organizer: 第36回日本比較内分泌学会大会
  • Place of Presentation: 都道府県会館・東京
  • Year and Date: 2011-11-24
• [Presentation] 無脊椎動物の脳におけるニューロステロイド合成:棘皮動物ヒトデの解析 (2011)
  • Author(s): 市丸修子、筒井和義, 他
  • Organizer: 第36回日本比較内分泌学会大会
  • Place of Presentation: 都道府県会館・東京
  • Year and Date: 2011-11-24
• [Presentation] 無脊椎動物の脳におけるニューロステロイド合成:頭足類マダコの解析 (2011)
  • Author(s): 喜多悠斗、筒井和義, 他
  • Organizer: 第36回日本比較内分泌学会大会
  • Place of Presentation: 都道府県会館・東京
  • Year and Date: 2011-11-24
• [Presentation] ステロイド性の雌イモリ誘引フェロモン (2011)
  • Author(s): 豊田ふみよ、筒井和義, 他
  • Organizer: 第36回日本比較内分泌学会大会
  • Place of Presentation: 都道府県会館・東京
  • Year and Date: 2011-11-24
• [Presentation] Bivalve mollusc gonadotropin-releasing hormone (2011)
  • Author(s): Kazuyoshi Tsutsui, et al
  • Organizer: 第36回日本比較内分泌学会大会
  • Place of Presentation: 都道府県会館・東京
  • Year and Date: 2011-11-24
• [Presentation] 生殖を制御する新規脳ホルモンGnIHの起源と分子進化 (2011)
  • Author(s): 筒井和義
  • Organizer: 第36回日本比較内分泌学会大会シンポジウム
  • Place of Presentation: 都道府県会館・東京
  • Year and Date: 2011-11-23
• [Presentation] 性分化疾患の分子基盤と臨床的対応 (2011)
  • Author(s): 緒方勤
  • Organizer: 第117回日本小児科学会甲信地方会
  • Place of Presentation: 甲府
  • Year and Date: 2011-11-20
• [Presentation] 子どもを取り巻く環境と小児の健康 (2011)
  • Author(s): 緒方勤
  • Organizer: 第40回Medical Photonics Seminar
  • Place of Presentation: 浜松
  • Year and Date: 2011-10-14
• [Presentation] キンカチョウの脳における26RFaペプチドの同定と機能解析 (2011)
  • Author(s): 戸張靖子、筒井和義, 他
  • Organizer: 第82回日本動物学会大会
  • Place of Presentation: 大雪アリーナ旭川
  • Year and Date: 2011-09-21
• [Presentation] メダカの脳における生殖腺刺激ホルモン放出抑制ホルモン(GnIH)cDNAのクローニング (2011)
  • Author(s): 岡村友貴、筒井和義, 他
  • Organizer: 第82回日本動物学会大会
  • Place of Presentation: 大雪アリーナ旭川
  • Year and Date: 2011-09-21
• [Presentation] ヤツメウナギの脳におけるLPXRFamideペプチドの同定と機能解析 (2011)
  • Author(s): 大杉知裕、筒井和義, 他
  • Organizer: 第82回日本動物学会大会
  • Place of Presentation: 大雪アリーナ旭川
  • Year and Date: 2011-09-21
• [Presentation] GnHはAC/cAMP/PKAシグナリングによりゴナドトロピン発現を抑制する (2011)
  • Author(s): ソン ユリ、筒井和義, 他
  • Organizer: 第82回日本動物学会大会
  • Place of Presentation: 大雪アリーナ旭川
  • Year and Date: 2011-09-21
• [Presentation] ストレスは生殖腺刺激ホルモン放出抑制ホルモン(GnIH)とその受容体の発現を増加させる (2011)
  • Author(s): 福田裕治郎、筒井和義, 他
  • Organizer: 第82回日本動物学会大会
  • Place of Presentation: 大雪アリーナ旭川
  • Year and Date: 2011-09-21
• [Presentation] ストレスによる脳内7alpha-ヒドロキシプレグネノロン合成の変動とその生理作用 (2011)
  • Author(s): 原口省吾、筒井和義, 他
  • Organizer: 第82回日本動物学会大会
  • Place of Presentation: 大雪アリーナ旭川
  • Year and Date: 2011-09-21
• [Presentation] テストステロンによる生殖腺刺激ホルモン放出抑制ホルモン(GnIH)受容体の発現制御機構 (2011)
  • Author(s): 水野貴信、筒井和義, 他
  • Organizer: 第82回日本動物学会大会
  • Place of Presentation: 大雪アリーナ旭川
  • Year and Date: 2011-09-21
• [Presentation] 雄イモリ腹腺由来ステロイドの雌誘引作用 (2011)
  • Author(s): 豊田ふみよ、筒井和義, 他
  • Organizer: 第82回日本動物学会大会
  • Place of Presentation: 大雪アリーナ旭川
  • Year and Date: 2011-09-21
• [Presentation] 遡上中のサケの脳では活動性を高める7alpha-ヒドロキシプレグネノロンの合成が高まる (2011)
  • Author(s): チャンジュンヒヨン、筒井和義, 他
  • Organizer: 第82回日本動物学会大会
  • Place of Presentation: 大雪アリーナ旭川
  • Year and Date: 2011-09-21
• [Presentation] プルキンエ細胞における7alpha-ヒドロキシプレグネノロン合成の変動とその制御機構 (2011)
  • Author(s): 奥山真一郎、筒井和義, 他
  • Organizer: 第82回日本動物学会大会
  • Place of Presentation: 大雪アリーナ旭川
  • Year and Date: 2011-09-21
• [Presentation] Neurosteroid biosynthesis and action during cerebellar development (2011)
  • Author(s): K.Tsutsui
  • Organizer: The 4th International Symposium : Society for Research on the Cerebellum
  • Place of Presentation: University of Tokyo, Tokyo, Japan
  • Year and Date: 2011-09-18
• [Presentation] 性分化疾患の分子基盤:update (2011)
  • Author(s): 緒方勤
  • Organizer: 第12回山陰内分泌研究会
  • Place of Presentation: 米子
  • Year and Date: 2011-09-16
• [Presentation] 性分化疾患の分子基盤 (2011)
  • Author(s): 緒方勤
  • Organizer: 第3回岐阜小児内分泌学術講演会
  • Place of Presentation: 岐阜
  • Year and Date: 2011-09-15
• [Presentation] 性分化疾患研究の進歩 (2011)
  • Author(s): 緒方勤
  • Organizer: 第81回京都内分泌同好会
  • Place of Presentation: 京都
  • Year and Date: 2011-09-03
• [Presentation] ヌーナン症候群とGH治療 (2011)
  • Author(s): 緒方勤
  • Organizer: ヌーナン症候群勉強会
  • Place of Presentation: 東京
  • Year and Date: 2011-08-27
• [Presentation] 子どもを取り巻く環境と健康 (2011)
  • Author(s): 緒方勤
  • Organizer: 浜松小児科医会
  • Place of Presentation: 浜松
  • Year and Date: 2011-07-27
• [Presentation] 乳幼児期および思春期の性について (2011)
  • Author(s): 緒方勤
  • Organizer: 第1回乳幼児発達指導研究会
  • Place of Presentation: 浜松
  • Year and Date: 2011-07-25
• [Presentation] SHOX遺伝子異常症 (2011)
  • Author(s): 緒方勤
  • Organizer: Update.Forum on Turner syndrome in Osaka
  • Place of Presentation: 大阪
  • Year and Date: 2011-07-23
• [Presentation] Melatonin regulates diurnal changes in locomotor activity by regulating 7alpha-hydroxypregnenolone synthesis in newts (2011)
  • Author(s): K.Tsutsui, et al
  • Organizer: The inaugural meeting of the North American Society for Comparative Endocrinology (NASCE 2011)
  • Place of Presentation: Michigan
  • Year and Date: 2011-07-15
• [Presentation] Identification, mode of action and functional significance of 7alpha-hydroxypregnenolone, a new key regulator of amphibian locomotion (2011)
  • Author(s): K.Tsutsui, H.Vaudry
  • Organizer: The 7th International Symposium on Amphibian and Reptilian Endocrinology and Neurobiology
  • Place of Presentation: University of Michigan, Ann Arbor, USA
  • Year and Date: 2011-07-12
• [Presentation] 7alpha-Hydroxypregnenolone acts as a serotonin-inducing factor to increase locomotor activity via corticosterone action under stress (2011)
  • Author(s): S.Haraguchi, K.Tsutsui, et al
  • Organizer: The 7th International Symposium on Amphibian and Reptilian Endocrinology and Neurobiology (ISAREN)
  • Place of Presentation: Michigan
  • Year and Date: 2011-07-12
• [Presentation] Genetic susceptibility to endocrine disrupters : Estrogen receptor polymorphisms (2011)
  • Author(s): Ogata T
  • Organizer: In : Hamamatsu DOHaD Conference
  • Place of Presentation: Hamamatsu, Japan
  • Year and Date: 2011-07-08
• [Presentation] 子どもの成長と成熟 (2011)
  • Author(s): 緒方勤
  • Organizer: 国際医療福祉大学熱海病院学術講演会
  • Place of Presentation: 熱海
  • Year and Date: 2011-07-01
• [Presentation] 中枢性性線機能低下症の基礎と臨床 (2011)
  • Author(s): 緒方勤
  • Organizer: 静岡産科婦人科学会春季学術集会
  • Place of Presentation: 静岡
  • Year and Date: 2011-06-05
• [Presentation] Discovery and evolutionary history of gonadotropin-inhibitory hormone (GnIH), a new key neuropeptide controlling reproduction (2011)
  • Author(s): K.Tsutsui
  • Organizer: The 8th International Congress of Comparative Physiology and Biochemistry (ICCPB2011)
  • Place of Presentation: Nagoya Congress Center, Nagoya, Japan
  • Year and Date: 2011-06-03
• [Presentation] ニューロステロイドの生合成とオーガナイジング作用 (2011)
  • Author(s): 筒井和義
  • Organizer: 第84回日本内分泌学会学術総会教育講演
  • Place of Presentation: 神戸国際会議場・神戸
  • Year and Date: 2011-04-22
• [Presentation] 生殖腺刺激ホルモン放出抑制ホルモン(GnIH)とリプロダクション:GnIHの発見と研究の進展、展望 (2011)
  • Author(s): 筒井和義
  • Organizer: 第1回沖縄生殖内分泌セミナー(第4回 沖縄リプロダクション研究会)
  • Place of Presentation: 沖縄
  • Year and Date: 2011-02-26
• [Presentation] 生体機能を調節する脳ホルモンの発見と理解の到達点 (2011)
  • Author(s): 筒井和義
  • Organizer: 新教育課程(生物)と最新の生物学セミナー
  • Place of Presentation: 大阪
  • Year and Date: 2011-02-11
• [Presentation] Disorders of Sex Development : Recent Progress. Plenary Lecture (2011)
  • Author(s): Ogata T
  • Organizer: In : The 13th European Congress of Endocrinology (ECE 2011)
  • Place of Presentation: Rotterdam Netherlands
• [Presentation] Genetic susceptibility to endocrine disrupters : Estrogen receptor polymorphisms (2011)
  • Author(s): Ogata T
  • Organizer: Plenary Lecture. In : 6^<th> Copenhagen Workshop on Endocrine Disrupters (COW 2011)
  • Place of Presentation: Copenhagen, Denmark
• [Presentation] 性ホルモン産生異常と性分化 (2011)
  • Author(s): 緒方勤
  • Organizer: 第84回日本内分泌学会学術総会教育講演
  • Place of Presentation: 神戸
• [Presentation] ターナー症候群を招く分子基盤 (2011)
  • Author(s): 緒方勤
  • Organizer: 日本人類遺伝学会第56回大会共催セミナー
  • Place of Presentation: 千葉
• [Presentation] 性分化疾患の臨床像と新規遺伝子MAMLD1の同定 (2011)
  • Author(s): 緒方勤
  • Organizer: 第28回日本医学会総会シンポジウム:内分泌疾患-病態解明と治療の進歩
  • Place of Presentation: 東京(東日本大震災のためDVD収録で配布)
• [Presentation] 脳の性分化に関する最近の知見 (2011)
  • Author(s): 緒方勤
  • Organizer: 第84回日本内分泌学会学術総会シンポジウム:性分化疾患の診断・治療戦略
  • Place of Presentation: 神戸
• [Presentation] 性分化疾患の発症機序 (2011)
  • Author(s): 緒方勤
  • Organizer: 第56回日本未熟児新生児学会学術集会:性分化疾患の新生児期管理
  • Place of Presentation: 東京
• [Presentation] Gonadotropin-inhibitory hormone (GnIH), a new key neurohormone controlling vertebrate reproduction : Biosynthesis, mode of action and functional significance (2011)
  • Author(s): K.Tsutsui
  • Organizer: The 2011 International Biomodulation Symposium on 'Biotechnology for Future Era'
  • Place of Presentation: Seoul National University, Seoul, Korea
• [Presentation] Gonadotropin-inhibitory hormone (GnIH), a new key neurohormone controlling vertebrate reproduction : Biosynthesis, mode of action and functional significance (2011)
  • Author(s): K.Tsutsui
  • Organizer: The 2011 International Biomodulation Symposium on 'Biomaterials and Biomodelling for Translational Research'. Seoul National University
  • Place of Presentation: Seoul, Korea
• [Presentation] Putting the brakes on reproduction. Implications for conservation? Global climate change? (2011)
  • Author(s): J.C.Wingfield, K.Tsutsui
  • Organizer: "Howard Bern Lecture" at the Society of Integrative and Comparative Biology (SICB) meeting 2011
  • Place of Presentation: Salt Lake City, USA
• [Presentation] GnRHとGnIHによる生殖神経内分泌制御.岡山大学研究開発委員会 (2010)
  • Author(s): 筒井和義
  • Organizer: 第4回ワーキング主催シンポジウム「分野・領域を超えた内分泌学・生殖内分泌学の研究ネットワーク」
  • Place of Presentation: 岡山
  • Year and Date: 2010-12-11
• [Presentation] 生殖腺刺激ホルモン放出抑制ホルモンGnIHによる生殖機能調節 (2010)
  • Author(s): 筒井和義
  • Organizer: 第55回日本生殖医学会総会および学術講演会
  • Place of Presentation: 徳島
  • Year and Date: 2010-11-12
• [Presentation] 生殖腺刺激ホルモン放出抑制ホルモンGnIH:発見、研究の進展と展望 (2010)
  • Author(s): 筒井和義
  • Organizer: 日本動物学会第81回大会 2010比較生理生化学の醍醐味～ICCPB2011国際比較生理生化学会に向けて～
  • Place of Presentation: 東京
  • Year and Date: 2010-09-24
• [Presentation] 性分化疾患の発症機序:遺伝-環境相互作用の観点から (2010)
  • Author(s): 緒方勤
  • Organizer: 第249回日本小児科学会東海地方会特別講演
  • Place of Presentation: 名古屋
  • Year and Date: 2010-05-16
• [Presentation] Kallmann syndrome : a one amino-acid insertion mutation of the fibroblast growth factor receptor 1 (FGFR1) acid box may affect neuronal extension in an FGF-dependent manner (2010)
  • Author(s): Sato N, Ogata T, 他
  • Organizer: The 14th International Congress of Endocrinology
  • Place of Presentation: Kyoto, Japan
• [Presentation] Endocrine Disruptors-the environment and its impact on paediatric endocrinology (2010)
  • Author(s): Ogata T
  • Organizer: The 6^<th> Bienniel Scientific Meeting of The Asia Pacific Paediatric Endocrinolgy
  • Place of Presentation: Xi'an, China
• [Presentation] Genetic causes of POF (2010)
  • Author(s): Ogata T
  • Organizer: October 16-17, 2010. Kyoto, Japan
  • Place of Presentation: Kyoto, Japan.
• [Presentation] 性分化疾患研究の最前線 (2010)
  • Author(s): 緒方勤
  • Organizer: 日本アンドロロジー学会第29回学術大会・第16回精子形成・精巣毒性研究会共同開催学会特別講演
  • Place of Presentation: 東京
• [Presentation] エコチル調査における遺伝医学研究 (2010)
  • Author(s): 緒方勤
  • Organizer: 日本人類遺伝学会第55回大会シンポジウム:小児環境疫学(エコチル)調査と遺伝医学
  • Place of Presentation: 大宮
• [Presentation] Novel molecular mechanisms underlying diurnal locomotor rhythms in birds : Coordination of melatonin with 7α-hydroxypregnenolone, a newly discovered avian neurosteroid (2010)
  • Author(s): K.Tsutsui
  • Organizer: Presenting at the 25th International Ornithological Congress.
  • Place of Presentation: Campos do Jordao, Brazil
• [Presentation] Discovery and evolutionary history of GnIH and kisspeptin, new key neuropeptides controlling reproduction (2010)
  • Author(s): K.Tsutsui
  • Organizer: The 7th International Congress of Neuroendocrinology
  • Place of Presentation: Rouen, France
• [Presentation] Discovery of GnIH : First Identification in Birds and Conservation in Mammals (2010)
  • Author(s): K.Tsutsui
  • Organizer: The Symposium "Gonadotropin inhibitory hormone (GnIH) functions in mammals" at The Endocrine Society's 92nd Annual Meeting
  • Place of Presentation: San Diego, California, USA
• [Book] 外性器と脳の性分化のメカニズム．有阪治（編）ビギナーのための小児内分泌診療ガイド (2014)
  • Author(s): 緒方勤
  • Total Pages: 10
  • Publisher: 中山書店
• [Book] スクエア 最新図説生物（二訂版）高等学校 (2014)
  • Author(s): 筒井和義
  • Total Pages: 344
  • Publisher: 第一学習社
• [Book] Turner症候群．吉川史隆，倉智博久，平松祐司（編）産婦人科疾患最新の治療 (2013)
  • Author(s): 緒方勤
  • Total Pages: 2
  • Publisher: 南江堂
• [Book] 性分化の分子生物学．吉田修（監），小川修、岡田裕作、荒井陽一、寺地敏郎、松田公志、筧義行、羽渕友則（編）ベッドサイド泌尿器科学 改定第4版 (2013)
  • Author(s): 緒方勤
  • Total Pages: 6
  • Publisher: 南江堂
• [Book] ヌーナン症候群．横谷進（編）成長障害のマネジメント 改定第3版 (2013)
  • Author(s): 緒方勤
  • Total Pages: 8
  • Publisher: 医薬ジャーナル社
• [Book] Gen. Comp. Endocrinol (2013)
  • Author(s): K. Tsutsui, P. J. Sharp, R. M. Dores
  • Total Pages: 235
  • Publisher: Gen. Comp. Endocrinol
• [Book] The E-Book of Neurosteroids: Frontiers Research Topic (2013)
  • Author(s): H. Vaudry, K. Tsutsui
  • Total Pages: 476
  • Publisher: Frontiers in Endocrinology (http://flashbook.frontiersin.org//clients/Frontiers/Neurosteroids/EBook.html)
• [Book] Neurosteroids and synaptic formation in the cerebellum. In: Handbook of Cerebellum and Cerebellar Disorders (2013)
  • Author(s): K. Tsutsui
  • Total Pages: 2397
  • Publisher: Springer
• [Book] Gonadotropin-inhibitory hormone (GnIH). In: The Handbook of Biologically Active Peptides (2nd edition) (2013)
  • Author(s): K. Tsutsui, T. Ubuka
  • Total Pages: 1943
  • Publisher: Elsevier publisher
• [Book] 26RFa. In: The Handbook of Biologically Active Peptides (2nd edition) (2013)
  • Author(s): J. Leprince, C. Neveu, B. Lefrance, L. Guilhaudis, I. Segalas-Milazzo, J.-C. Do Rego, M. Tena-Sempere, K. Tsutsui, H. Vaudry
  • Total Pages: 1943
  • Publisher: Elsevier publisher
• [Book] 高等学校新生物基礎 (2012)
  • Author(s): 筒井和義(監修)
  • Total Pages: 176
  • Publisher: 第一学習社
• [Book] 高等学校生物基礎 (2012)
  • Author(s): 筒井和義(監修)
  • Total Pages: 304
  • Publisher: 第一学習社
• [Book] Neurosteroids and synaptic formation in the cerebellum (2010)
  • Author(s): K.Tsutsui
  • Publisher: Springer(印刷中)
• [Book] Phylogenetic Aspects of Neuropeptides : From Invertebrates to Humans (2010)
  • Author(s): K.Tsutsui
  • Total Pages: 300
  • Publisher: Blackwell
• [Book] 性分化疾患における遺伝カウンセリング (2010)
  • Author(s): 緒方勤
  • Publisher: メディカルドゥ(印刷中)
• [Book] 原発性性腺機能低下 (2010)
  • Author(s): 緒方勤
  • Publisher: 医学書院(印刷中)
• [Book] ターナー症候群 (2010)
  • Author(s): 緒方勤
  • Publisher: 中山書店(印刷中)
• [Book] クラインフェルター症候群 (2010)
  • Author(s): 緒方勤
  • Publisher: 中山書店(印刷中)
• [Remarks] 浜松医大小児科
  • URL: http://www2.hama-med.ac.jp/w1b/pediatr/patient/index.html
• [Remarks] 国立成育医療研究センター分子内分泌研究部
  • URL: http://www.nch.go.jp/endocrinology/index.htm
• [Remarks] 早稲田大学
  • URL: http://www.f.waseda.jp/k-tsutsui/
• [Remarks] 浜松医科大学小児科
  • URL: http://www2.hama-med.ac.jp/w1b/pediatr/patient/index.html
• [Remarks] 国立成育医療研究センター研究所分子内分泌研究部
  • URL: http://www.nch.go.jp/endocrinology/index.htm
• [Remarks] 早稲田大学筒井研究室
  • URL: http://www.f.waseda.jp/k-tsutsui/
• [Remarks]
  • URL: http://www2.hama-med.ac.jp/wlb/pediatr/patient/index.html
• [Remarks]
  • URL: http://www.nch.go.jp/endocrinology/index.htm
• [Remarks]
  • URL: http://www.f.waseda.jp/k-tsutsui/
• [Remarks]
  • URL: http://www.nch.go.jp/endocrinology/index.htm
• [Remarks]
  • URL: http://www.f.waseda.jp/k-tsutsui/