| Budget Amount *help |
¥158,340,000 (Direct Cost: ¥121,800,000、Indirect Cost: ¥36,540,000)
Fiscal Year 2016: ¥27,560,000 (Direct Cost: ¥21,200,000、Indirect Cost: ¥6,360,000)
Fiscal Year 2015: ¥27,560,000 (Direct Cost: ¥21,200,000、Indirect Cost: ¥6,360,000)
Fiscal Year 2014: ¥29,250,000 (Direct Cost: ¥22,500,000、Indirect Cost: ¥6,750,000)
Fiscal Year 2013: ¥32,630,000 (Direct Cost: ¥25,100,000、Indirect Cost: ¥7,530,000)
Fiscal Year 2012: ¥41,340,000 (Direct Cost: ¥31,800,000、Indirect Cost: ¥9,540,000)
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| Outline of Final Research Achievements |
The Bacterial flagellar motor is a supramolecular complex and exists at the base of flagellum in the cytoplasmic membrane. Bacteria can move by rotating the flagella as a screw. We revealed important residues of the stator and rotor proteins for the energy conversion of motor which is rotated by the sodium ion flow. Furthermore, we found that stator protein derived from the super thermophilic bacterium, which is thought to have branched at a very early stage of the evolutionary phylogenetic tree, can function in Escherichia coli. This gave the new concept on the origin of the flagellar motor. Furthermore, by precise measurement of rotation of the flagellar motor, we obtained the new insight of energy conversion mechanism when the stator and rotor interact with each other.
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