| Co-Investigator(Kenkyū-buntansha) |
水間 広 国立研究開発法人理化学研究所, 生命機能科学研究センター, 研究員 (00382200)
疋島 啓吾 沖縄科学技術大学院大学, 実験動物セクション, MRIスペシャリスト (30420219)
崔 翼龍 国立研究開発法人理化学研究所, 生命機能科学研究センター, ユニットリーダー (60312229)
林 拓也 国立研究開発法人理化学研究所, ライフサイエンス技術基盤研究センター, ユニットリーダー (50372115)
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| Budget Amount *help |
¥73,450,000 (Direct Cost: ¥56,500,000、Indirect Cost: ¥16,950,000)
Fiscal Year 2018: ¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Fiscal Year 2017: ¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Fiscal Year 2016: ¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Fiscal Year 2015: ¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Fiscal Year 2014: ¥24,570,000 (Direct Cost: ¥18,900,000、Indirect Cost: ¥5,670,000)
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| Outline of Final Research Achievements |
In order to identify the functional structure of the brain from pathological animal models such as non-human primates and genetically modified mice, we developed dedicated coils for animals MRI imaging and also developed new molecular probes in PET. In combination with other technologies, we established a method for delineating the dynamic changes in functional network and its causality. Using this non-invasive imaging methods, we analyzed functional neural networks in genetically modified model mice and non-human primates such as macaques, and not only pathologies, but also neural circuits under the transition in the learning and development stages and functional recovery after the brain and spinal cord injury.
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