| Project/Area Number |
10660264
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied animal science
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| Research Institution | IWATE UNIVERSITY |
|---|
Principal Investigator |
ODA Shinichi Iwate University, Faculty of Agriculture, Associate Professor, 農学部, 助教授 (60211827)
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| Co-Investigator(Kenkyū-buntansha) |
SATOH Jun Iwate University, Faculty of Agriculture, Assistant Professor, 農学部, 助手 (30250632)
ITOH Kikukatsu Iwate University, Faculty of Agriculture, Lecturer, 農学部, 講師 (50232434)
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| Project Period (FY) |
1998 – 1999
|
| Project Status |
Completed (Fiscal Year 1999)
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| Budget Amount *help |
¥2,800,000 (Direct Cost: ¥2,800,000)
Fiscal Year 1999: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1998: ¥2,100,000 (Direct Cost: ¥2,100,000)
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| Keywords | calf / SGLT-1 / glucose absorption / weaning / α-glucosidase / β-galactosidase |
|---|
| Research Abstract |
In the small intestine, the brush-border NaィイD1+ィエD1/glucose cotransporters (SGLT-1) play a major role in the absorption of glucose . The objectives of this experiment were to investigate the developmental changes of the intestinal function for glucose absorption and to recognize the assay for SGLT-1 in new born calves. The SGLT-1mRNA was determined by Northern blot analysis . The mucosal SGLT-1mRNA levels were lower in duodenum and gradually increased in proximal intestine before weaning calves. After normal weaning at 5 weeks old , the expression of SGLT-1 in the small intestine was not different between the location of intestine. Changes in α-glucosidase and β-galactosidase activities in the small intestine were also determined. α-glucosidase activity was lower in suckling calves than that of weaned calves , but β-galactosidase activity remained constant during these period.
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