| Project/Area Number |
11680806
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
神経・脳内生理学
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| Research Institution | MIE UNIVERSITY |
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Principal Investigator |
YAMAMOTO Tetsuro Mie University Faculty of Medicine, Professor, 医学部, 教授 (00127002)
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| Co-Investigator(Kenkyū-buntansha) |
KAYAHARA Tetsuro Mie University Faculty of Medicine, Lecturer, 医学部, 講師 (20024705)
SHIBUYA Hiroshi Mie University Faculty of Medicine, Assistant, 医学部, 助手 (60262622)
NISHIMURA Yoshihiro Mie University Faculty of Medicine, Associate Professor, 医学部, 助教授 (40172704)
中野 勝磨 三重大学, 医学部, 教授 (30024623)
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| Project Period (FY) |
1999 – 2000
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| Project Status |
Completed (Fiscal Year 2000)
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| Budget Amount *help |
¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 2000: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1999: ¥2,900,000 (Direct Cost: ¥2,900,000)
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| Keywords | BASAL GANGLIA / CEREBELLAR NUCLEI / MOTOR CORTEX / INTRACELLULAR RECORDING / INTERACTION / MOTOR CONTROL / MEMBRANE POTENTIAL CHANGES / 膜電位変化 |
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| Research Abstract |
Intracellular recordings and staining were performed from pyramidal neurons of motor cortex and related areas in cats, monkeys and rats to investigate the interaction between the cerebellar and basal ganglia inputs. Experiments were done under pentobarbital anesthesia in in vivo preparations on stimulation of cerebellar nuclei and basal ganglia. To obtain the morphological data, we also used anterograde tract tracing method with various tracers. In the beginning of the project, we tried to record from two neurons simultaneously, but it was rather difficult from technical point of view, so we compared the responsiveness of neurons in the motor cortex and those of premotor areas as well as in vitro preparations.
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