Supramolecular flow chemistry; A novel and practical self-assembly system coupled with non-equilibrium phenomena in microflow channel

• Project/Area Number: 15H03532
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Nanomaterials chemistry
• Research Institution: Kyoto Prefectural University
• Principal Investigator: Numata Munenori 京都府立大学, 生命環境科学研究科, 准教授 (70423564)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000); Fiscal Year 2017: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000); Fiscal Year 2016: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000); Fiscal Year 2015: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
• Keywords: 超分子制御 / 非平衡科学 / マイクロフロー / 超分子化学 / 非平衡過程 / 速度支配 / 超分子科学 / 水素結合 / 時空間制御 / 非平衡系 / 準安定構造 / 超分子重合 / ナノファイバー / 非平衡 / 非平衡開放系

Outline of Final Research Achievements

Rapid and uniform diffusion of solvent molecules as well as of protons can be coupled with up-hill self-assembly from less active molecules and/or under low concentration conditions. We have demonstrated that porphyries and perylene bisimide derivatives undergo effective self-assembly in microflow channels coupling with the unique diffusion phenomena. In order to make supramolecular chemistry more practical, exploiting novel self-assembly systems is strongly desired. The present approaches will lead to new research fields in supramolecular chemistry.

Research Products

• [Journal Article] Water-Induced Self-Assembly of an Amphiphilic Perylene Bisimide Dyad into Vesicles, Fibers, Coils, and Rings (2018)
  • Author(s): M. Ogasawara, X. Lin, H. Kurata, H. Ouchi, M. Yamauchi, T. Ohba, T. Kajitani, T. Fukushima, M. Numata, R. Nogami, B. Adhikari, S. Yagai
  • Journal Title: Mater. Chem. Front. Volume: 2 Issue: 1 Pages: 171-179
  • DOI: 10.1039/c7qm00494j
  • Peer Reviewed / Open Access
• [Journal Article] Enhanced self-assembly abilities coupled with nano- and micro-scale non-equilibrium phenomena in flowing micro fields (2018)
  • Author(s): M. Numata, R. Nogami, A. Kitamura
  • Journal Title: Chem Nano Mat. Volume: 4 Issue: 2 Pages: 175-182
  • DOI: 10.1002/cnma.201700281
  • Peer Reviewed
• [Journal Article] Flowing microenvironment regulate the helical pitch of a semi-artificial polymer (2016)
  • Author(s): M. Numata, N. Hirose
  • Journal Title: RSC Adv Volume: 6 Issue: 70 Pages: 6551965623-6551965623
  • DOI: 10.1039/c6ra12944g
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Supramolecular Chemistry in Microflow Fields: Toward A New Material World of Precise Kinetic Control (2015)
  • Author(s): M. Numata
  • Journal Title: Chem. Asian J. Volume: 10 Issue: 12 Pages: 2574-2588
  • DOI: 10.1002/asia.201500555
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] マイクロ非平衡環境における超分子制御の可能性 (2018)
  • Author(s): 沼田宗典
  • Organizer: 東京工業大学集中講義・化学科セミナー
  • Invited
• [Presentation] 流しながら集積化するマイクロフロー超分子化学の可能性 (2018)
  • Author(s): 沼田宗典
  • Organizer: 静岡大学 ナノ・マイクロ横断型人材育成セミナー
  • Invited
• [Presentation] 非平衡マイクロ空間における会合促進効果の検証 (2017)
  • Author(s): 北村彬智・野上梨絵・沼田宗典
  • Organizer: 日本科学会第９７春季年会
  • Place of Presentation: 慶應大学日吉キャンパス（神奈川県 横浜市）
  • Year and Date: 2017-03-16
• [Presentation] 非平衡マイクロ空間を利用した準安定構造の制御 (2017)
  • Author(s): 加地 真伍・佐藤 暁子・野上 梨絵・中堂薗 拓哉・沼田 宗典
  • Organizer: 日本科学会第９７春季年会
  • Place of Presentation: 慶應大学日吉キャンパス（神奈川県 横浜市）
  • Year and Date: 2017-03-16
• [Presentation] 同時性相互作用が引き起こす超分子会合の増強と長距離秩序の創発 (2017)
  • Author(s): 浅井淳志・酒井良一郎・神崎千沙子・沼田宗典
  • Organizer: 日本科学会第９７春季年会
  • Place of Presentation: 慶應大学日吉キャンパス（神奈川県 横浜市）
  • Year and Date: 2017-03-16
• [Presentation] 非平衡環境がもたらす高分子間相互作用の増幅効果とそれを利用した階層性超分子構造の構築 (2017)
  • Author(s): 沼田宗典
  • Organizer: 第６６回高分子討論会
• [Presentation] マイクロ空間が拓く超分子化学の新展開 (2017)
  • Author(s): 沼田宗典
  • Organizer: 関西学院大学 パイスター分子制御による未来型物質変換研究拠点 ２０１７年度公開シンポジウム
  • Invited
• [Presentation] “Creation of hierarchical molecular architectures in microfluidic device” (2016)
  • Author(s): Atsushi Asai, Yuri Nishino, Munenori Numata, Eiji Nakata, Akihiko Kimura
  • Organizer: The 7th International Symposium of Advanced Energy Science
  • Place of Presentation: Kyoto University, Uji Campus (Uji, Kyoto)
  • Year and Date: 2016-09-05
  • Int'l Joint Research
• [Presentation] “Creation of kinetically stabilized porphyrin microfilms through synchronized hydrogen-bonding interactions in microflow” (2016)
  • Author(s): Yuri Nishino,Atsushi Asai, and Munenori Numata
  • Organizer: 12th International Workshop on Supramolecular Nanoscience of Chemically Programmed Pigments(SNCPP16)
  • Place of Presentation: Ritsumeikan University (Kusatsu, Shiga)
  • Year and Date: 2016-06-17
  • Int'l Joint Research
• [Presentation] “Flowing microenvironments regulate the pitch of a semi-artificial helical polymer” (2016)
  • Author(s): Naoya Hirose, Takuya Nakadozono, and Munenori Numata
  • Organizer: 12th International Workshop on Supramolecular Nanoscience of Chemically Programmed Pigments(SNCPP16)
  • Place of Presentation: Ritsumeikan University (Kusatsu, Shiga)
  • Year and Date: 2016-06-17
  • Int'l Joint Research
• [Presentation] マイクロ空間を利用した”energy input”分子集積による高活性超分子の創製 (2016)
  • Author(s): 沼田宗典・野上梨絵・佐藤暁子・中堂薗拓哉・浅井淳志
  • Organizer: 第１４回ホスト・ゲスト化学シンポジウム
  • Place of Presentation: 高知城ホール（高知県 高知市）
  • Year and Date: 2016-06-04
• [Presentation] マイクロ空間内の迅速なプロトン拡散過程を利用した水素結合性ナノマテリアルの創製 (2016)
  • Author(s): 西野 友里・浅井 淳志・沼田 宗典
  • Organizer: 日本化学会第９６春季年会
  • Place of Presentation: 同志社大学
  • Year and Date: 2016-03-24
• [Presentation] マイクロサイズの流れによるらせん高分子のコンフォメーション制御 (2016)
  • Author(s): 廣瀬 直弥・中堂薗 拓哉・沼田 宗典
  • Organizer: 日本化学会第９６春季年会
  • Place of Presentation: 同志社大学
  • Year and Date: 2016-03-24
• [Presentation] マイクロ空間を利用する超分子制御の可能性について (2016)
  • Author(s): 沼田 宗典・野上 梨絵・佐藤 暁子
  • Organizer: 日本化学会第９６春季年会
  • Place of Presentation: 同志社大学
  • Year and Date: 2016-03-24
• [Presentation] マイクロフロー空間を利用するπ集積過程の制御 (2016)
  • Author(s): 北村 彬智・沼田 宗典
  • Organizer: 日本化学会第９６春季年会
  • Place of Presentation: 同志社大学
  • Year and Date: 2016-03-24
• [Presentation] マイクロ空間を利用する超分子制御の可能性 (2015)
  • Author(s): 沼田宗典
  • Organizer: 第１３回ホスト・ゲスト化学シンポジウム
  • Place of Presentation: 東北大学
  • Year and Date: 2015-06-06
• [Book] Beta-Glucans, Applications, Effects and Research; Supramolecular Wrapping by Beta-(1-3)-D-Glucans toward Polysaccharide-Based Functional Materials (2016)
  • Author(s): M. Numata, K. Sugikawa, S. Haraguchi, T. Shiraki, S. Tamaru, S. Tamesue and S. Shinkai
  • Total Pages: 57
  • Publisher: Nova Science Publishers
• [Book] Boron- Sensing, Synthesis and Supramolecular Self-Assembly; Polymer Self-Assembly Mediated by Boronic Acid (2015)
  • Author(s): M. Numata (ed. by M. Li, J. S. Fossey, and T. D. James)
  • Total Pages: 416
  • Publisher: Royal Society of Chemistry