Explore of developmental index for infant sleep between premature and one year old

• Project/Area Number: 15H05086
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Lifelong developmental nursing
• Research Institution: Nagasaki University
• Principal Investigator: ETO Hiromi 長崎大学, 医歯薬学総合研究科(保健学科), 教授 (10213555)
• Research Collaborator: HORIUCHI Shigeko ; NISHIHARA Kyoko
• Project Period (FY): 2015-04-01 – 2019-03-31
• Project Status: Completed (Fiscal Year 2018)
• Budget Amount: ¥13,910,000 (Direct Cost: ¥10,700,000、Indirect Cost: ¥3,210,000); Fiscal Year 2018: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000); Fiscal Year 2017: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000); Fiscal Year 2016: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2015: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
• Keywords: 早産児 / 睡眠・覚醒 / 睡眠発達 / 行動分析 / 乳児 / ビデオソムノグラフィ / ディベロップメンタルケア / 乳幼児突然死症候群 / 睡眠 / 未熟児

Outline of Final Research Achievements

This study examined preterm infants' sleep development during NICU/GCU hospitalization to one year after birth. We examine quiet sleep, active sleep, and wakefulness during their first one year.
During hospitalization, it was recognized decrease of Active sleep (REM sleep) , increase of Quiet sleep (NREM sleep) , and self-soothing ability. The sleep developed over time, and the circadian rhythm was formed around 25 weeks after birth. However, it was suggested that more Active sleep and delay of the circadian rhythm formation compare to infants after the same life.

Academic Significance and Societal Importance of the Research Achievements

本研究では、早産児の生後早期の入院中から1歳までの継続した睡眠覚醒の発達を示した。早産児の１年間のフォローアップという点では、対象数が少数ではあったが貴重であり、学術的意義は大きいと考える。また、ビデオ録画という客観的データを用いて、睡眠発達を示すことができた点では本邦初であり、サーカディアンリズムの形成時期などを分析し、今後のディベロップメンタルケアにつながる視点を得られた点では意義がある。

Research Products

• [Journal Article] The outline of “Japan Academy of Midwifery: Evidence-based guidelines for midwifery care in pregnancy and childbirth – 2016 edition” (2018)
  • Author(s): Mariko Iida, Yaeko Kataoka, Hiromi Eto, Yuriko Tadokoro, Yuko Masuzawa, Yukari Yaju, Hiromi Asai, Ayaka Sakurai, Shigeko Horiuchi
  • Journal Title: Journal of Japan Academy of Midwifery Volume: 32 Issue: 1 Pages: 73-80
  • DOI: 10.3418/jjam.JJAM-2017-0038
  • NAID: 130007412748
  • ISSN: 0917-6357, 1882-4307
  • Year and Date: 2018-06-29
  • Peer Reviewed
• [Journal Article] Maternal and neonatal outcomes in birth centers versus hospitals among low-risk pregnancies in Japan: A retrospective cohort study (2018)
  • Author(s): Yaeko Kataoka, Yuko Masuzawa, Chiho Kato, Hiromi Eto
  • Journal Title: Japan Journal of Nursing Science Volume: 15 Issue: 1 Pages: 91-96
  • DOI: 10.1111/jjns.12171
  • Peer Reviewed
• [Journal Article] Influences of fetal movement on a pregnant woman’s sleep: Using fetal movement acceleration measurement recorder (2017)
  • Author(s): Kyoko Nishihara, Hiromi Eto, Shigeko Horiuchi
  • Journal Title: Journal of Sleep Research Volume: 26 Issue: S1 Pages: 47-47
  • DOI: 10.1111/jsr.38_12619
  • Peer Reviewed
• [Journal Article] Factors Contributing to Postpartum Blood-loss in Low-risk Mothers through Expectant Management in Japanese Birth Centers (2016)
  • Author(s): Hiromi Eto, Ayako Hasegawa, Yaeko Kataoka, Sarah E. Porter
  • Journal Title: Women and Birth Volume: 22 Issue: 4 Pages: 1-7
  • DOI: 10.1016/j.wombi.2016.11.003
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A cross-sectional survey of policies guiding second stage labor in urban Japanese hospitals, clinics and midwifery birth centers. (2016)
  • Author(s): Kaori Baba, Yaeko Kataoka, Kaori Nakayama, Yukari Yaju, Shigeko Horiuchi, Hiromi Eto
  • Journal Title: BMC Pregnancy and Childbirth Volume: 16:37 Issue: 1 Pages: 1-13
  • DOI: 10.1186/s12884-016-0814-2
  • Peer Reviewed / Open Access
• [Presentation] 早産児のNICU入院中から生後25週までの睡眠発達の推移 (2019)
  • Author(s): 真名子優香, 江藤宏美
  • Organizer: 第33回日本助産学会学術集会
• [Presentation] NICU入院中の早産児の昼夜の睡眠推移 (2018)
  • Author(s): 江藤宏美, 真名子優香
  • Organizer: 第18回日本赤ちゃん学会学術集会
• [Presentation] Infants' sleep development during the 1 year after birth under nocturnal co-sleep conditions (2018)
  • Author(s): Hiromi Eto, Yuuka Manago, Chiho Kato, Kyoko Nishihara
  • Organizer: 24th Congress of European Sleep Research Society
  • Int'l Joint Research
• [Presentation] Influences of fetal movement on a pregnant woman’s sleep: Using fetal movement acceleration measurement recorder (2017)
  • Author(s): Kyoko Nishihara, Hiromi Eto, Shigeko Horiuchi
  • Organizer: Sleep DownUnder 2017
  • Int'l Joint Research
• [Presentation] Sleeping Behavior of New Born and Infants; Synchronization during Pregnancy, Puerperal Period and Child-Bearing Period (2017)
  • Author(s): Hiromi Eto
  • Organizer: 2nd International Seminar on Global Health (ISGH)
  • Int'l Joint Research / Invited
• [Presentation] 早産児の早期睡眠発達の推移とその影響因子について (2017)
  • Author(s): 阿部莉子, 江藤宏美
  • Organizer: 第17回日本赤ちゃん学会学術集会
• [Presentation] 妊娠中期以降の妊婦における夜間の胎動の推移 (2017)
  • Author(s): 田中希実, 江藤宏美
  • Organizer: 第17回日本赤ちゃん学会学術集会
• [Presentation] NICUにおける疼痛刺激を伴う処置とstateの変化 (2017)
  • Author(s): 梅野志帆, 江藤宏美
  • Organizer: 第17回日本赤ちゃん学会学術集会
• [Presentation] Sleep transition of co-sleeping infant nighttime sleep-wake condition from 2-25 weeks (2015)
  • Author(s): Hiromi Eto, Aya Sakono
  • Organizer: Eighth Annual Pediatric Sleep Medicine Conference
  • Place of Presentation: Amelia Island (Florida, US)
  • Year and Date: 2015-11-13
  • Int'l Joint Research
• [Presentation] Sleep development for infants from two weeks after birth to twenty-five weeks (2015)
  • Author(s): Aya Sakono, Akari Hayashi, Hiromi Eto
  • Organizer: 11th ICM (International Confederation of Midwives) Asia Pacific Regional Conference
  • Place of Presentation: パシフィコ横浜（神奈川）
  • Year and Date: 2015-07-20
  • Int'l Joint Research
• [Presentation] Change over time in mother’s response to infant at night (2015)
  • Author(s): Moemi Kai, Akari Hayashi, Hiromi Eto
  • Organizer: 11th ICM (International Confederation of Midwives) Asia Pacific Regional Conference
  • Place of Presentation: パシフィコ横浜（神奈川）
  • Year and Date: 2015-07-20
  • Int'l Joint Research
• [Book] オールカラー改訂２版 標準ディベロップメンタルケア (2018)
  • Author(s): 日本ディベロップメンタルケア（DC）研究会
  • Total Pages: 320
  • Publisher: メディカ出版
  • ISBN: 9784840465281