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Development of the detection method for animal cysticercosis and the investigation of the genetic factors for host specificity

Research Project

Project/Area Number 15H05261
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Veterinary medical science
Research InstitutionYamaguchi University

Principal Investigator

Yanagida Tetsuya  山口大学, 共同獣医学部, 准教授 (40431837)

Co-Investigator(Kenkyū-buntansha) 迫 康仁  旭川医科大学, 医学部, 教授 (40312459)
伊藤 亮  旭川医科大学, 医学部, 客員教授 (70054020)
岡本 宗裕  京都大学, 霊長類研究所, 教授 (70177096)
佐藤 宏  山口大学, 共同獣医学部, 教授 (90211945)
水上 洋一  山口大学, 大学研究推進機構, 教授 (80274158)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000)
Fiscal Year 2017: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2015: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Keywords嚢虫症 / テニア症 / 無鉤条虫 / アジア条虫 / 血清検査 / 宿主特異性 / 人獣共通感染症 / 条虫 / 感染症 / 寄生虫 / 疫学調査
Outline of Final Research Achievements

In this study, it was aimed to develop the detection method for cysticercosis, caused by Taenia saginata or Taenia asiatica, in cattle and pigs. Field surveys in the endemic areas were conducted using the developed serology, and it revealed the method can detect T. saginata cysticercosis in cattle. Further extensive surveys are needed to examine the sensitivity and specificity of the method, and whether the method can detect T. asiatica cysticercosis in pig.
It was for the first time directly demonstrated that cattle can be the intermediate host for the hybrid descendant between T. saginata and T. asiatica. This study indicates the possibility that comparative genomics can reveal the genetic factors controlling the host specificity of T. saginata and T. asiatica.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • Research Products

    (13 results)

All 2017 2016 2015 Other

All Int'l Joint Research (6 results) Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Acknowledgement Compliant: 2 results) Presentation (5 results) (of which Int'l Joint Research: 3 results,  Invited: 2 results)

  • [Int'l Joint Research] ラオス国立大学/ラオス国立公衆衛生院(ラオス)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] ラオス国立大学(ラオス)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] ウダヤナ大学(インドネシア)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] ウダヤナ大学(インドネシア)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] マヒドン大学(タイ)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] 四川省寄生虫病研究所(中国)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Swine cysticercosis in the Karangasem district of Bali, Indonesia: An evaluation of serological screening methods2016

    • Author(s)
      Kadek Swastika, Nyoman Sadra Dharmawan, I. Ketut Suardita, I. Nengah Kepeng, Toni Wandra, 1, Yasuhito Sako, Munehiro Okamoto, Tetsuya Yanagida, Mizuki Sasaki, Patrick Giraudoux, Minoru Nakao, Takahiko Yoshida, Luh Putu Eka Diarthini, I. Made Sudarmaja, Ivan Elisabeth Purba, Christine M. Budke, Akira Ito
    • Journal Title

      Acta Tropica

      Volume: 163 Pages: 46-53

    • DOI

      10.1016/j.actatropica.2016.07.022

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Recent advances and perspectives in molecular epidemiology of Taenia solium cysticercosis2016

    • Author(s)
      Ito A, Yanagida T, Nakao M.
    • Journal Title

      Infection, Genetics and Evolution

      Volume: 40 Pages: 357-367

    • DOI

      10.1016/j.meegid.2015.06.022

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] ラオス・セポン郡における家畜嚢虫症調査2017

    • Author(s)
      柳田哲矢, 迫康仁, Phonepadith X, Vannaphone P, Khampason N, 伊藤亮, 佐藤宏, 岡本宗裕
    • Organizer
      日本寄生虫学会西日本支部大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Helminths in pigs: The Impact of Taenia solium and Taenia asiatica in Asia2017

    • Author(s)
      Ito A.
    • Organizer
      Joint International Tropical Medicine Meeting 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Advances in basic and applied science towards the control of zoonotic cestodiases: the importance of basic research.2017

    • Author(s)
      Ito A.
    • Organizer
      International Symposium on Cestode Zoonosis Control
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] バリ島およびニューギニア島における有鉤条虫の遺伝的多様性とその起源2016

    • Author(s)
      柳田 哲矢, Swastika K, Dharmawan NS, Wandra T, 佐藤 宏, 迫 康仁, 伊藤 亮, 岡本 宗裕
    • Organizer
      第85回日本寄生虫学会大会
    • Place of Presentation
      宮崎市民プラザ(宮崎県宮崎市)
    • Year and Date
      2016-03-19
    • Related Report
      2015 Annual Research Report
  • [Presentation] Cestode zoonoses, echinococcoses and cysticercosis: the importance of molecular approach2015

    • Author(s)
      Ito A, Yanagida T, Nakao M.
    • Organizer
      Joint International Tropical Medicine Meeting 2015
    • Place of Presentation
      Amari Watergate Bangkok(タイ バンコク)
    • Year and Date
      2015-12-02
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research

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Published: 2015-04-16   Modified: 2019-03-29  

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