| Budget Amount *help |
¥23,790,000 (Direct Cost: ¥18,300,000、Indirect Cost: ¥5,490,000)
Fiscal Year 2017: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000)
|
|---|
| Outline of Final Research Achievements |
Iron is an essential mineral for the body and its deficient is the problem in the world. Iron is also the risk factor of oxidative stress when accumulated in the organs excessively. In this study, the global analysis of gene expression in the liver or whole blood showed that patterns of gene expression profiles were changed according to the amount of iron storage in the organs. In the liver, a variety of metabolic processes and immune responses tended to change. In the whole blood, we focused on the genes of which expression patterns were correlated significantly with iron storage in the organs as candidates to evaluate the iron status in the body.
|
