Analysis of multi time-scale dynamics in mechanobiological stimulation by impulsive force
| Project/Area Number |
15H05352
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | The University of Tokyo |
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Principal Investigator |
Nakagawa Keiichi 東京大学, 大学院工学系研究科(工学部), 助教 (00737926)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥24,440,000 (Direct Cost: ¥18,800,000、Indirect Cost: ¥5,640,000)
Fiscal Year 2016: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2015: ¥21,320,000 (Direct Cost: ¥16,400,000、Indirect Cost: ¥4,920,000)
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| Keywords | メカノバイオロジー / メカニカルストレス / 撃力 / レーザー / カルシウムイメージング / 再生医療 / 再生医工学 |
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| Outline of Final Research Achievements |
In recent years, studies that clarify the mechanical action on the living body and aim at understanding diseases and applying them to medical treatment are actively conducted. In this study, we developed an impulsive force loading system to investigate how the instantaneous mechanical stimulus affects cells. Cells are given nanometer and microsecond scale displacement by a cantilever accelerated by nanosecond laser. We also acheved observation of a cell response with calcium imaging.
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Report
(3 results)
Research Products
(4 results)
