| Budget Amount *help |
¥23,920,000 (Direct Cost: ¥18,400,000、Indirect Cost: ¥5,520,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000)
Fiscal Year 2015: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
|
|---|
| Outline of Final Research Achievements |
Chronic social defeat is a widely used animal model with high etiological and discriminative validity that evokes profound behavioral phenotypes. In this study, we examined how social defeat stress alters physiological activity in freely moving rats. Our recording system integrates local field potential signals from the cortex, heartbeat signals, and skeletal muscle signals into an electrical interface board that is mounted on an animal’s head. After receiving a physical attack from the resident rat, the heart rate of the intruder animals was transiently increased and then decreased when they started to show freezing behavior. During the freezing period, brain local field potential power was prominently reduced. The evidence will advance the understanding of the neurophysiological correlate of mind-body associations during mental stress exposure.
|
