Patterned Naofibers for cell culture by plasma treatment
| Project/Area Number |
15H06586
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Materials/Mechanics of materials
|
|---|
| Research Institution | Keio University |
|---|
Principal Investigator |
Maeda Tomoki 慶應義塾大学, 理工学部(矢上), 助教 (00754730)
|
|---|
| Project Period (FY) |
2015-08-28 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
|---|
| Keywords | ナノファイバ / エレクトロスピニング法 / パターニング / 表面改質 / プラズマ処理 / エレクトロスピニング / 細胞培養 / 機械材料・材料力学 / 材料加工・処理 / ナノ材料 / 高分子構造・物性 |
|---|
| Outline of Final Research Achievements |
In this study, the patterning method of electrospun nanofibers by plasma treatment was developed. Additionally, the cell culture on the patterned nanofibers was examined.
The PDMS surface was partially modified by using a mask during the plasma treatment. Then, the nanofibers were spun using the treated PDMS as a collector. As a result, the patterned nanofibers were obtained on the PDMS substrate. By adjusting the condition of plasma treatment and electrospinning, the patterned area became clearer. Furthermore, cells were cultured on the patterned nanofibers. As a result, the cell proliferation was enhanced on the patterned nanofibers as compared to the untreated surface.
|
Report
(3 results)
Research Products
(20 results)
