| Project/Area Number |
15H06809
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Functional basic dentistry
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| Research Institution | Kanagawa Dental University Junior College |
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Principal Investigator |
Yuko Yamamoto 神奈川歯科大学短期大学部, その他部局等, 講師 (60756568)
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| Project Period (FY) |
2015-08-28 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 唾液 / IgA / 難消化性糖類 / 短鎖脂肪酸 / 盲腸内容物 / フラクトオリゴ糖 / ポリデキストロース / 盲腸内容物水分量 / 盲腸内容物粘度 / 炎症性サイトカイン / 歯学 / 免疫学 / 栄養学 / 食物繊維 |
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| Outline of Final Research Achievements |
In the experiment which intake of the fructo-oligosaccharide addition diets of rats,this study results sugested that the weight and submandibular gland weight, furthermore the short chain fatty acid (metabolism product) which fermentation promoted in the cecum by the fructo-oligosaccharide intake affect for the salivary IgA level increase.In the later experiments which intake of the polydextrose + lactitol and polydextrose 4% addition diets of rats, these studys results suggested that the absorption rate of the short chain fatty acids in the cecum affected for the salivary IgA level increase,furthermore, cecum tissue weight and water content of cecul digesta,the viscosity of cecul digesta affected for the absorption rate of the short chain fatty acids in the cecum.
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