Development of a hydrodyanamically levitated centrifugal blood pump using force balance

• Project/Area Number: 15K01305
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Biomedical engineering/Biomaterial science and engineering
• Research Institution: National Institute of Advanced Industrial Science and Technology
• Principal Investigator: Kosaka Ryo 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 (10415680)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 人工心臓 / 血液ポンプ / 動圧軸受 / 血液適合性 / 流体軸受 / 流体力 / 軸受隙間 / 多円弧軸受 / 磁気力 / 永久磁石

Outline of Final Research Achievements

The purpose of the present study is to improve levitation performance in a hydrodynamically levitated centrifugal blood pump by changing the thrust force balance on the impeller. As a result, we confirmed that the hemocompatibility of the developed hydrodynamically levitated centrifugal blood pump was improved by balancing the resultant force acting on the impeller.

Research Products

• [Journal Article] 動圧浮上遠心血液ポンプの軸受隙間内ヘマトクリット算出法の有効性評価 (2017)
  • Author(s): 村重 智崇, 迫田 大輔, 小阪 亮, 西田 正浩, 川口 靖夫, 山根 隆志, 丸山 修
  • Journal Title: ライフサポート Volume: 29 Pages: 42-48
  • NAID: 130007626920
  • Peer Reviewed
• [Journal Article] Bearing gap adjustment for improvement of levitation performance in a hydrodynamically levitated centrifugal blood pump (2015)
  • Author(s): Kosaka R, Yoshida F, Nishida M, Maruyama O, Kawaguchi Y, Yamane
  • Journal Title: Proceedings of the IEEE EMBC Volume: 37 Pages: 3295-3298
  • DOI: 10.1109/embc.2015.7319096
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] 人工心臓装着患者に対する安心・安全技術 (2018)
  • Author(s): 小阪 亮、迫田 大輔、西田 正浩、丸山 修
  • Organizer: LS-BT2018講演会
• [Presentation] R&D of Life Sci. and Biotech. in AIST (2018)
  • Author(s): 小阪 亮
  • Organizer: Japan MedTech Meetup Seminar
  • Int'l Joint Research / Invited
• [Presentation] Hyper-Spectral Imagingを用いた動圧浮上遠心血液ポンプの急性動物実験による血液適合性評価 (2017)
  • Author(s): 小阪 亮、迫田 大輔、藤原 立樹、村重 智崇、西田 正浩、田原 禎生、大内克洋、荒井 裕国、丸山 修
  • Organizer: 第45回人工心臓と補助循環懇話会学術集会
  • Place of Presentation: 華やぎの章慶山(山梨県)
  • Year and Date: 2017-02-17
• [Presentation] Hydrodynamically levitated centrifugal blood pump (2017)
  • Author(s): 小阪 亮
  • Organizer: 日米亜医療機器イノベーションフォーラム
  • Int'l Joint Research
• [Presentation] Evaluation of hemocompatibility of a hydrodynamically levitated centrifugal blood pump using hyperspectral imaging in acute animal studies (2017)
  • Author(s): Kosaka R, Sakota D, Fujiwara T, Murashige T, Nishida M, Tahara T, Ouchi K, Arai H, Maruyama O.
  • Organizer: 44th Congress of European Society for Artificial Organs (ESAO)
  • Int'l Joint Research
• [Presentation] Hydraulic force balance for improvement of a levitation performance of an impeller in a hydrodynamically levitated centrifugal blood pump (2015)
  • Author(s): Kosaka R, Sakota D, Nishida M, Ouchi K, Fujiwara T, Arai H, Maruyama O, Yamane T
  • Organizer: International Society for Rotary Blood Pumps 2015
  • Place of Presentation: Dubrovnik (Croatia)
  • Year and Date: 2015-09-27
  • Int'l Joint Research
• [Presentation] Bearing gap adjustment for improvement of levitation performance in a hydrodynamically levitated centrifugal blood pump (2015)
  • Author(s): Kosaka R, Yoshida F, Nishida M, Maruyama O, Kawaguchi Y, Yamane T
  • Organizer: 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
  • Place of Presentation: Milano (Italy)
  • Year and Date: 2015-08-25
  • Int'l Joint Research
• [Presentation] 多円弧動圧軸受を有する動圧浮上遠心血液ポンプの血液適合性評価 (2015)
  • Author(s): 小阪 亮、安井 和哉、西田 正浩、丸山 修、山根 隆志
  • Organizer: 第54回日本生体医工学会大会
  • Place of Presentation: 名古屋（愛知県）
  • Year and Date: 2015-05-07