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Predicting Work Outcome in Patients with Schizophrenia

Research Project

Project/Area Number 15K04109
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Clinical psychology
Research InstitutionFukushima University

Principal Investigator

Sumiyoshi Chika  福島大学, 人間発達文化学類, 教授 (20262347)

Project Period (FY) 2015-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords統合失調症 / 機能的転帰 / 高次認知機能 / 労働 / 意味記憶 / カテゴリ流暢性 / 労働状態 / 生活の質 / 認知機能 / 確率予測モデル / 就労
Outline of Final Research Achievements

The purposes of the study were to investigate factors to predict work outcome and to examine the accuracy of the perdition in patients with schizophrenia. The method to evaluate higher-order cognition was also studied to explore the effective variable(s) in the prediction. Logistic regression analysis showed that cognitive decline, psychiatric symptoms, and social function were significant variables to predict work status (work hours per week) in patients with schizophrenia. Overall, estimation was accurate yielding 70-80% accuracy. Singular value decomposition (SVD) analysis was applied to category fluency data to explore effective variable(s) of higher-order cognition to be used in predicting work outcome. The SVD analysis suggested that cosine value was the useful variable, revealing irregularity of the semantic memory organization in patients with schizophrenia.

Academic Significance and Societal Importance of the Research Achievements

社会的意義:本邦での精神疾患患者の就労状況は、欧米に比べ良好とはいえない。本研究は、精神疾患患者の労働状態について客観的データを提供することにより、研究面から当事者・雇用者の支援に寄与する。
学術的意義:本研究では、統合失調症患者の高次認知機能評価指標を得るために、テキストマイニング手法(特異値分解法)を試みた。従来、主として人文科学で利用されてきた同手法の精神医学分野への応用は、文理融合型研究を推進するものである。

Report

(6 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (25 results)

All 2019 2018 2017 2016 2015

All Journal Article (7 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 5 results,  Open Access: 5 results,  Acknowledgement Compliant: 1 results) Presentation (18 results) (of which Int'l Joint Research: 6 results,  Invited: 1 results)

  • [Journal Article] Predicting work outcome in patients with schizophrenia: Influence of IQ decline.2018

    • Author(s)
      Sumiyoshi C, Fujino H, Yamamori H, Kudo N, Azechi H, Fujimoto M, Yasuda Y, Ohi K, Sumiyoshi T, Hashimoto R.
    • Journal Title

      Schizophr Res

      Volume: 201 Pages: 172-179

    • DOI

      10.1016/j.schres.2018.05.042

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Semantic Memory Organization in Japanese Patients With Schizophrenia Examined With Category Fluency2018

    • Author(s)
      Sumiyoshi Chika、Fujino Haruo、Sumiyoshi Tomiki、Yasuda Yuka、Yamamori Hidenaga、Fujimoto Michiko、Hashimoto Ryota
    • Journal Title

      Frontiers in Psychiatry

      Volume: 9 Pages: 1-10

    • DOI

      10.3389/fpsyt.2018.00087

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Brief Assessment of Intelligence Decline in Schizophrenia As Represented by the Difference between Current and Premorbid Intellectual Quotient2017

    • Author(s)
      Ohi Kazutaka、Sumiyoshi Chika、Fujino Haruo、Yasuda Yuka、Yamamori Hidenaga、Fujimoto Michiko、Sumiyoshi Tomiki、Hashimoto Ryota
    • Journal Title

      Frontiers in Psychiatry

      Volume: 8 Pages: 1-10

    • DOI

      10.3389/fpsyt.2017.00293

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 統合失調症の注意特性2017

    • Author(s)
      住吉 チカ
    • Journal Title

      Clinical Neuroscience

      Volume: 35 Pages: 1005-1010

    • Related Report
      2017 Research-status Report
  • [Journal Article] Usefulness of the Wechsler Intelligence Scale short form for assessing functional outcomes in patients with schizophrenia.2016

    • Author(s)
      Sumiyoshi C, Fujino H, Sumiyoshi T, Yasuda Y, Yamamori H, Ohi K, Fujimoto M, Takeda M, Hashimoto R.
    • Journal Title

      Psychiatry Res

      Volume: 245 Pages: 371-378

    • DOI

      10.1016/j.psychres.2016.08.018

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] どのように認知機能を評価するか?2015

    • Author(s)
      住吉チカ・住吉太幹
    • Journal Title

      精神科治療学

      Volume: 30 Pages: 1433-1442

    • Related Report
      2015 Research-status Report
  • [Journal Article] Factors predicting work outcome in Japanese patients with schizophrenia: role of multiple functioning levels2015

    • Author(s)
      Chika Sumiyoshi, Philip D. Harvey, Manabu Takaki, Yuko Okahisa, Taku Sato, Ichiro Sora, Keith H. Nuechterlein, Kenneth L.. Subotnik, Tomiki Sumiyoshi
    • Journal Title

      Schizophrenia Research: Cognition

      Volume: 2 Issue: 3 Pages: 105-112

    • DOI

      10.1016/j.scog.2015.07.003

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] Association between Work Status and Subjective Aspects of Recovery in Patients with Schizophrenia: A Longitudinal Study2019

    • Author(s)
      Chika Sumiyoshi, Kazutaka Ohi, Haruo Fujino, Hidenaga Yamamori, Noriko Kudo, Hirotsugu Azech, Michiko Fujimoto, Yuka Yasuda, Tomiki Sumiyoshi, Ryota Hashimoto
    • Organizer
      2019 Congress of the Schizophrenia International Research Society
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 認知機能障害による精神疾患のバイオタイプ分類は可能か2019

    • Author(s)
      住吉チカ
    • Organizer
      第49回日本神経精神薬理学会年会
    • Related Report
      2019 Annual Research Report
  • [Presentation] カテゴリ流暢性課題を利用した統合失調症患者の高次認知機能の評価:最近の研究動向2019

    • Author(s)
      住吉チカ, 松井三枝, 倉知正佳, 橋本亮太, 吉村直記, 住吉太幹
    • Organizer
      第19回認知機能研究会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 統合失調症患者の記憶の組織化に対する経頭蓋直流刺激の改善効果2019

    • Author(s)
      住吉チカ, 成田瑞, 長谷川由美, 稲川拓磨, 山田悠至, 末吉一貴, 上田奈津貴, 大町佳永, 横井優磨, 住吉太幹
    • Organizer
      第14回日本統合失調症学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 統合失調症患者の高次認知機能に対する経頭蓋直流刺激の改善効果2019

    • Author(s)
      住吉チカ, 成田瑞, 長谷川由美, 稲川拓磨, 山田悠至, 末吉一貴, 上田奈津貴, 大町佳永, 横井優磨, 住吉太幹
    • Organizer
      第41回日本生物学的精神医学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Predictive Accuracy for Work Outcome in Patients with Schizophrenia: The Examination Based on Functioning Levels2018

    • Author(s)
      Chika Sumiyoshi, Haruo Fujino, Hidenaga Yamamori, Noriko Kudo, Hirotsugu Azechi, Michiko Fujimoto, Yuka Yasuda, Kazutaka Ohi, Tomiki Sumiyoshi , Ryota Hashimoto
    • Organizer
      生物学的精神医学会
    • Related Report
      2018 Research-status Report
  • [Presentation] 統合失調症患者の労働状態:推定精度に関わる要因2018

    • Author(s)
      住吉 チカ, 藤野 陽生, 山森 英長, 工藤 紀子, 畦地裕統, 藤本 美智子, 安田 由華, 大井一高, 住吉 太幹, 橋本 亮太
    • Organizer
      精神疾患と認知機能研究会
    • Related Report
      2018 Research-status Report
  • [Presentation] Predictive Accuracy for Work Outcome in Patients with Schizophrenia2018

    • Author(s)
      Chika Sumiyoshi, Haruo Fujino, Tomiki Sumiyoshi, Hidenaga Yamamori, Noriko Kudo, Hirotsugu Azechi, Michiko Fujimoto, Yuka Yasuda, Kazutaka Ohi, Ryota Hashimoto
    • Organizer
      Schizophrenia International Research Society
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] Impact of Intellectual Decline on Work Outcome in Patients with Schizophrenia2017

    • Author(s)
      Chika Sumiyoshia, Tomiki Sumiyoshi, Haruo Fujino, Hidenaga Yamamori, Yuka Yasuda, Noriko Kudo, Michiko Fujimoto, Manabu Ikeda, Ryota Hashimoto
    • Organizer
      16th International Congress on Schizophrenia Research
    • Place of Presentation
      San Diego (California, USA)
    • Year and Date
      2017-03-24
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 統合失調症患者における労働状態の予測:知能低下の影響2017

    • Author(s)
      住吉 チカ、藤野 陽生、住吉 太幹、山森 英長、工藤 紀子、畦地 裕統、 藤本 美智子、安田 由華、橋本 亮太
    • Organizer
      第17回精神疾患と認知機能研究会
    • Related Report
      2017 Research-status Report
  • [Presentation] 統合失調症における労働状態の予測因子2016

    • Author(s)
      住吉チカ・藤野陽生・住吉太幹・山森英長・工藤紀子・藤本美智子・安田由華・橋本亮太
    • Organizer
      第16回精神疾患と認知機能研究会
    • Place of Presentation
      海運クラブビル(東京, 千代田区)
    • Year and Date
      2016-11-04
    • Related Report
      2016 Research-status Report
  • [Presentation] SemantiSemantic memory organization in Japanese patients with schizophrenia examined with category fluency2016

    • Author(s)
      Chika Sumiyoshi, Haruo Fujino, Tomiki Sumiyoshi, Yuka Yasuda, HidenagaYamamori, Kazutaka Ohi, Michiko Fujimoto, Ryota Hashimoto
    • Organizer
      31st International Congress of Psychology
    • Place of Presentation
      Pacifico Yokohama (Yokohama, Japan)
    • Year and Date
      2016-07-24
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] カテゴリ流暢性課題に基づく意味記憶構造の推定,2016

    • Author(s)
      住吉チカ・藤野陽生・住吉太幹・山森英長・藤本美智子・安田由華・大井一高・橋本亮太
    • Organizer
      第27回日本発達心理学会大会
    • Place of Presentation
      北海道大学(札幌, 北区)
    • Year and Date
      2016-04-29
    • Related Report
      2016 Research-status Report
  • [Presentation] シンポジウム:認知機能と社会機能をつなぐもの:評価の手法2016

    • Author(s)
      住吉 チカ
    • Organizer
      CEPD研究会
    • Place of Presentation
      国立精神・神経医療研究センター(東京都・小平市)
    • Year and Date
      2016-03-12
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 統合失調症患者の就労に関わる要因とその回復目標2015

    • Author(s)
      住吉チカ, Philip D. Harvey, 高木 学, 岡久祐子, 佐藤 拓, 曽良一郎, Kenneth L. Subotnik, Keith H. Nuechterlein, 住吉太幹
    • Organizer
      第15回精神疾患と認知機能研究会
    • Place of Presentation
      海運クラブビル (東京都・千代田区)
    • Year and Date
      2015-11-01
    • Related Report
      2015 Research-status Report
  • [Presentation] 統合失調症患者と健常者の意味記憶構造の比較:カテゴリ流暢性課題に基づく比較2015

    • Author(s)
      住吉チカ, 藤野陽生, 住吉太幹, 橋本亮太
    • Organizer
      日本心理学会大会
    • Place of Presentation
      名古屋国際会議場(愛知県・名古屋市)
    • Year and Date
      2015-09-22
    • Related Report
      2015 Research-status Report
  • [Presentation] Brief versions of the Wechsler Intelligence Scale for schizophrenia: relation to functional outcome2015

    • Author(s)
      Chika Sumiyoshi, Haruo Fujino, Tomiki Sumiyoshi, Yuka Yasuda, Hidenaga Yamamori, Kazutaka Ohi, Michiko Fujimoto, Ryota Hashimoto, Masatoshi Takeda
    • Organizer
      日本神経科学会大会
    • Place of Presentation
      神戸国際会議場(兵庫県・神戸市)
    • Year and Date
      2015-07-28
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Functional Recovery in Patients with Schizophrenia: Predicting Factors for Work Outcome2015

    • Author(s)
      Chika Sumiyoshi, Philip D. Harvey, Manabu Takaki, Yuko Okahisa, Taku Sato, Ichiro Sora, Keith H. Nuechterlein, Kenneth L.. Subotnik, Tomiki Sumiyoshi
    • Organizer
      International Congress on Schizophrenia Research
    • Place of Presentation
      Broadmoor Hotel (Colorado Springs, USA)
    • Year and Date
      2015-04-01
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research

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Published: 2015-04-16   Modified: 2021-02-19  

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