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Studies on the construction of taste transmission pathway from taste receptor cells to taste nerves and the role of ATP

Research Project

Project/Area Number 15K07429
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Food science
Research InstitutionKyoto University

Principal Investigator

Hayashi Yukako  京都大学, 農学研究科, 准教授 (60212156)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordssour / taste / ATP / synapse / transduction / nerve / 味覚 / 情報伝達 / 酸味 / セロトニン / ATP受容 / 味受容細胞 / III型味細胞 / 味情報伝達 / 味細胞 / 酸味受容
Outline of Final Research Achievements

Type II taste receptive cells that receive sweet, umami and bitterness do not form synapse with taste nerves, and type III taste receptive cells that accept sour taste form synapses with taste nerve. Taste information is transmitted from type III cells via serotonin. These type III cells make synapse with the taste nerve.
From the result of previous studies, type III cells have been differentiated into "ATP receptor type III cell" and "sour taste receptor type III cell". To investigate whether it is communicating system are in the "sour taste receptive" type III cells. That is, it was suggested that "sour taste receptive" type III cells did not synapse with taste nerve.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (6 results)

All 2017 2016

All Presentation (6 results) (of which Int'l Joint Research: 4 results,  Invited: 1 results)

  • [Presentation] セロトニンの局在性の観察によるIII型味細胞-味神経間の情報伝達機構の解明2017

    • Author(s)
      藤本典大、林由佳子
    • Organizer
      日本味と匂い学会第51回大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Immunohistochemical Localization of Serotonin in Two types of Type III taste cells2017

    • Author(s)
      Fujimoto Norihiro and Yukako Hayashi
    • Organizer
      The 16th International Symposium on Molecular and Neural Mechanisms. of Taste and Olfactory Perception
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Type III taste cells could be reclassified by the function2017

    • Author(s)
      Yukako Hayashi and Fujimoto Norihiro
    • Organizer
      The 16th International Symposium on Molecular and Neural Mechanisms. of Taste and Olfactory Perception
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] マウス味細胞と味神経間の情報伝達機構の解明2017

    • Author(s)
      藤本典大、清水英憲、林由佳子
    • Organizer
      日本農芸化学会
    • Place of Presentation
      京都市、京都
    • Related Report
      2016 Research-status Report
  • [Presentation] The Signal of Sour Taste have Specific Route to Gustatory Nerve Fivers2016

    • Author(s)
      Norihiro Fujimoto, Hidenori Shimizu, Yukako Hayashi
    • Organizer
      International Symposium on Olfaction and Taste
    • Place of Presentation
      横浜市, 神奈川
    • Year and Date
      2016-06-05
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Immunohistochemical Localization of Serotonin in Taste Buds of Circumvallate Papillae in mice2016

    • Author(s)
      Fujimoto N., Shimizu H., Kitada R., Hayashi Y.
    • Organizer
      International Symposium on Olfaction and Taste 2016
    • Place of Presentation
      横浜、日本
    • Year and Date
      2016-06-05
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research

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Published: 2015-04-16   Modified: 2019-03-29  

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