Isolation of genes expressed asymmetrically in flounder metamorphosis and regulation by thyroid hormone
| Project/Area Number |
15K07571
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Aquatic life science
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| Research Institution | Tohoku University |
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Principal Investigator |
Yokoi Hayato 東北大学, 農学研究科, 助教 (40569729)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | ヒラメ / 変態 / 異体類 / 次世代シーケンサー / 次世代シーケンス解析 / 発生 |
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| Outline of Final Research Achievements |
Flounder transform their body plan during metamorphosis; right eye migrates to the other side and pigment cells differentiate only in the ocular side. Gene expression profile were compared between ocular and blind side in tissues around supra orbital bar at early metamorphic stage and skin and muscle tissue at later metamorphic stage in order to isolate genes expressed asymmetrically between ocular and blind side. Candidate genes were further analyzed by in situ hybridization and suggested that genes might be involved in right side specific degeneration of supra orbital bar and genes that genes might be involved in ocular side specific pigment cell differentiation.
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Report
(4 results)
Research Products
(59 results)
