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Discovery of zoonotic filariases derived from wild animals with the use of blood-sucking insects as vectors

Research Project

Project/Area Number 15K07781
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Integrative animal science
Research InstitutionOita University

Principal Investigator

FUKUDA Masako  大分大学, 医学部, 助教 (00156788)

Co-Investigator(Kenkyū-buntansha) 大塚 靖  鹿児島大学, 国際島嶼教育研究センター, 准教授 (00244161)
Research Collaborator TAKAOKA Hiroyuki  
UNI Shigehiko  
SAEUNG Atiporn  
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords野生動物 / 人獣共通感染症 / 吸血性昆虫 / ブユ / フィラリア / オンコセルカ
Outline of Final Research Achievements

To determine the vector of Onchocerca dewittei japonica (the causative agent of zoonotic onchocercosis in Japan) from wild boar, blood source animals of black flies attracted to wild boar baits were investigated by molecular analysis. As a result, anthropophilic Simulium bidentatum, a possible natural vector of this zoonosis in Japan, was confirmed to bite wild boars and to be the vector species. Moreover, to predict and prevent zoonotic filarial infections, the fauna of black flies and their natural infections with filarial larvae were investigated in several places in Japan. This study indicates that the collection of blood-sucking insects is a useful tool for searching for zoonotic filariasis.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (18 results)

All 2018 2017 2016 2015 Other

All Int'l Joint Research (6 results) Journal Article (3 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 3 results,  Open Access: 3 results,  Acknowledgement Compliant: 2 results) Presentation (9 results)

  • [Int'l Joint Research] マラヤ大学(マレーシア)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] チェンマイ大学(タイ)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] マラヤ大学(マレーシア)

    • Related Report
      2016 Research-status Report
  • [Int'l Joint Research] チェンマイ大学(タイ)

    • Related Report
      2016 Research-status Report
  • [Int'l Joint Research] マラヤ大学(マレーシア)

    • Related Report
      2015 Research-status Report
  • [Int'l Joint Research] チェンマイ大学(タイ)

    • Related Report
      2015 Research-status Report
  • [Journal Article] Morphological and molecular characteristics of Malayfilaria sofiani Uni, Mat Udin & Takaoka n. g., n. sp. (Nematoda: Filarioidea) from the common treeshrew Tupaia glis Diard & Duvaucel (Mammalia: Scandentia) in Peninsular Malaysia2017

    • Author(s)
      Uni S, Mat Udin AS, Agatsuma T, Saijuntha W, Junker K, Ramli R, Omar H, Lim YA, Sivanandam S, Lefoulon E, Martin C, Belabut DM, Kasim S, Abdullah Halim MR, Zainuri NA, Bhassu S, Fukuda M, Matsubayashi M, Harada M, Low VL, Chen CD, Suganuma N, Hashim R, Takaoka H, Azirun MS
    • Journal Title

      Parasite Vectors

      Volume: 10 Issue: 1 Pages: 1-14

    • DOI

      10.1186/s13071-017-2105-9

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Onchocerca takaokai n. sp. (Nematoda: Filarioidea) in Japanese wild boars (Sus scrofa leucomystax): Description and molecular identification of intradermal females2015

    • Author(s)
      Shigehiko Uni, Masako Fukuda, Takeshi Agatsuma, Odile Bain, Yasushi Otsuka, Jun Nakatani, Makoto Matsubayashi, Masashi Harada, Hasmahzaiti Omar, Rosli Ramli, Rosli Hashim, Mohd Sofian Azirun, Hiroyuki Takaoka
    • Journal Title

      Parasitology International

      Volume: 64 Issue: 6 Pages: 493-502

    • DOI

      10.1016/j.parint.2015.07.001

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] A new case of zoonotic onchocercosis in northern Kyushu, Japan2015

    • Author(s)
      Masako Fukuda, Shigehiko Uni, Yasushi Otsuka, Yuki Eshita, Jun Nakatani, Kazuhiko Ihara, Yasuji Yoshikawa, Mizuki Goto, Sakuhei Fujiwara, Rosli Ramli, Mohd Sofian Azirun, Hiroyuki Takaoka
    • Journal Title

      Parasitology International

      Volume: 64 Issue: 6 Pages: 519-521

    • DOI

      10.1016/j.parint.2015.07.006

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] 奄美大島におけるブユ幼虫の季節消長2018

    • Author(s)
      大塚 靖、福田昌子、高岡宏行
    • Organizer
      第70回日本衛生動物学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 福島県で見いだされたOnchocerca dewittei japonicaによる人獣共通感染症2018

    • Author(s)
      福田昌子、宇仁茂彦、猪狩貴弘、内海康文、大塚 靖、長谷川英男、高岡宏行
    • Organizer
      第70回日本衛生動物学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] マレー半島のツパイ(Tupaia glis)より見いだした新属新種のフィラリアMalayfilaria sofianiの形態および分子系統学的特徴2018

    • Author(s)
      宇仁茂彦、Ahmad Syihan Mat Udin、吾妻 健、Weerachai Saijuntha、Naruemon Bunchom、Yvonne Ai-Lian Lim、福田昌子、Rosli Ramli、宇賀 昭二、高岡宏行、Mohd Sofian Azirun
    • Organizer
      第87回日本寄生虫学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 大分県におけるイノシシ囮法を用いたブユ成虫の採集2017

    • Author(s)
      福田昌子、大塚 靖、高岡宏行
    • Organizer
      第69回日本衛生動物学会大会
    • Place of Presentation
      長崎大学医学部ポンペ会館(長崎県長崎市)
    • Year and Date
      2017-04-15
    • Related Report
      2016 Research-status Report
  • [Presentation] 奄美大島におけるブユの季節消長と日中活動の人囮法による調査2017

    • Author(s)
      大塚 靖、福田昌子、高岡宏行
    • Organizer
      第69回日本衛生動物学会大会
    • Place of Presentation
      長崎大学医学部ポンペ会館(長崎県長崎市)
    • Year and Date
      2017-04-15
    • Related Report
      2016 Research-status Report
  • [Presentation] 広島県におけるブユ成虫のフィラリア自然感染の調査2017

    • Author(s)
      福田昌子、石沢久遠、加藤 秀、大塚 靖、堤 寛、高岡宏行
    • Organizer
      第70回日本寄生虫学会南日本支部大会・第67回日本衛生動物学会南日本支部大会合同大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 大分県でイノシシ囮法により採集されたブユ成虫の吸血源動物の同定2016

    • Author(s)
      福田昌子、大塚 靖、高岡宏行
    • Organizer
      第69回日本寄生虫学会南日本支部大会・第66回日本衛生動物学会南日本支部大会合同大会
    • Place of Presentation
      佐賀大学医学部看護学科棟(佐賀県佐賀市)
    • Year and Date
      2016-11-06
    • Related Report
      2016 Research-status Report
  • [Presentation] 大分県でイノシシ囮法により採集されたキアシツメトゲブユ成虫の吸血源動物の同定2016

    • Author(s)
      福田昌子、大塚 靖、高岡宏行
    • Organizer
      第68回日本衛生動物学会大会
    • Place of Presentation
      栃木県総合文化センター (栃木県宇都宮市)
    • Year and Date
      2016-04-17
    • Related Report
      2015 Research-status Report
  • [Presentation] 大分県の野外で採集したキアシツメトゲブユ成虫に見いだされたオンコセルカ幼虫の分子同定2015

    • Author(s)
      福田昌子、大塚 靖、高岡宏行
    • Organizer
      第68回日本寄生虫学会南日本支部大会・第65回日本衛生動物学会南日本支部大会合同大会
    • Place of Presentation
      長崎大学医学部ポンペ会館 (長崎県長崎市)
    • Year and Date
      2015-10-17
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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