| Project/Area Number |
15K07880
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Fukuyama University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
波多江 典之 北海道医療大学, 薬学部, 准教授 (30449912)
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| Research Collaborator |
NISHIYAMA Takashi
HIRONAKA Miharu
TANINAKA Kimiko
OBATA Manami
TAKAIWA Shuuya
MURAKAMI Mari
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 電子環状反応 / マイクロ波 / 縮合複素環 / Azafluorenone / Protoberberine / Pyrrolo[2,3-c]quinoline / azafluorenone / onychine / protoberberine / alanglumkloid A / alanglumkloid B / pyrrolo[2,3-c]quinoline / marinoquinoline / Phenanthridine / amphimedine / electrocyclization / microwave |
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| Outline of Final Research Achievements |
It was utilized as a key reaction for the core structure construction of heterocyclic natural products targeting two synthetic methods and was developed to total synthesis. We also conducted activity evaluation using a series of novel compounds, and conducted search research on drug target molecules.
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