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Hormonal control of locomotor behavior in the ventromedial nucleus of the hypothalamus.

Research Project

Project/Area Number 15K08204
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Environmental physiology(including physical medicine and nutritional physiology)
Research InstitutionOsaka Yuhigaoka Gakuen College (2017)
University of Fukui (2015-2016)

Principal Investigator

Narita Kazumi  大阪夕陽丘学園短期大学, その他部局等, 准教授(移行) (80270958)

Co-Investigator(Kenkyū-buntansha) 重松 陽介  福井大学, 医学部, 教授 (80162593)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsオキシトシン / 行動量 / 視床下部 / 運動量 / レプチン / 視床下部腹内側核 / 歩行運動 / 絶食
Outline of Final Research Achievements

Preliminary research revealed that there is a site that causes voluntary movement in the hypothalamus of the rat brain. In this study we searched for substances that regulate the activity of this site. It was revealed that oxytocin, a posterior pituitary hormone, enhances and leptin, an adipocyte hormone, inhibits the activity of this brain region and locomotor activity.
Exercise is very important for healthy life. But it is difficult to start exercise. When the results of this research is applied to people, it will become easy to start exercise, and it can be expected to greatly help to maintain health.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (1 results)

All 2016

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results)

  • [Journal Article] The ventromedial hypothalamus oxytocin induces locomotor behavior regulated by estrogen2016

    • Author(s)
      Narita K, Murata T, Matsuoka S
    • Journal Title

      Physiol Behav

      Volume: 9384 Pages: 30297-9

    • DOI

      10.1016/j.physbeh.2016.05.047

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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