Breast cancer cohort study

• Project/Area Number: 15K08713
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Epidemiology and preventive medicine
• Research Institution: Okayama University
• Principal Investigator: TAIRA NARUTO 岡山大学, 大学病院, 准教授 (50467734)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 乳癌 / ライフスタイル / 予後 / QOL / 代替療法 / 身体活動 / 乳がん / サバイバーシップ / 生活習慣 / コホート研究 / 前向きコホート研究 / 情報ニーズ / 飲酒 / 喫煙

Outline of Final Research Achievements

The primary purpose of this large cohort study is to investigate the effects on breast cancer outcomes of modifiable lifestyle factors after breast cancer diagnosis. These factors include physical activity, smoking, alcohol consumption, obesity and weight gain after diagnosis, alternative medicine, and dietary factors.Women diagnosed with Stage 0 to Ⅲ breast cancer are eligible for participation to this study. Life style, alternative medicine, psychosocial factor, reproductive factors, and HRQoL are assessed using questionnaire at breast cancer diagnosis, and 1, 2, 3 and 5 years after diagnosis.A longitudinal multi-institutional prospective cohort study of lifestyle, alternative medicine, psychosocial and reproductive factors, and HRQoL is planned using a questionnaire for 5 years after breast cancer diagnosis. The primary endpoint will be disease-free survival.Patient recruitment commenced in February 2013 and 1942 breast cancer patients were enrolled.

Research Products

• [Journal Article] Rainbow of KIBOU (ROK) study: a Breast Cancer Survivor Cohort in Japan. (2018)
  • Author(s): Mizota Y, Ohashi Y, Iwase T, Iwata H, Sawaki M, Kinoshita T, Taira N, Mukai H, Yamamoto S.
  • Journal Title: Breast Cancer Volume: 25 Issue: 1 Pages: 60-67
  • DOI: 10.1007/s12282-017-0784-x
  • Peer Reviewed / Open Access
• [Journal Article] Impact of modifiable lifestyle factors on outcomes after breast cancer diagnosis: the Setouchi Breast Cancer Cohort Study. (2015)
  • Author(s): Taira N, Akiyama I, Ishihara S, Ishibe Y, Kawasaki K, Saito M, Shien T, Nomura T, Hara F, Mizoo T, Mizota Y, Yamamoto S, Ohsumi S, Doihara H; Executive Committee for the Setouchi Breast Cancer Cohort Study.
  • Journal Title: Jpn J Clin Oncol Volume: 45 Pages: 600-602
  • DOI: 10.1093/jjco/hyv033
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Remarks] 希望の虹プロジェクト
  • URL: http://rok.ncc.go.jp/index2.html