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Effects of fetal and early childhood environment on childhood obesity and adult non-communicable diseases from the epidemiological view

Research Project

Project/Area Number 15K08731
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Epidemiology and preventive medicine
Research InstitutionAichi Medical University (2016-2017)
University of Yamanashi (2015)

Principal Investigator

Suzuki Kohta  愛知医科大学, 医学部, 教授 (90402081)

Co-Investigator(Kenkyū-buntansha) 平田 修司  山梨大学, 大学院総合研究部, 教授 (00228785)
山縣 然太朗  山梨大学, 大学院総合研究部, 教授 (10210337)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
KeywordsDOHaD説 / 疫学 / コホート研究 / 母子保健 / マルチレベル解析
Outline of Final Research Achievements

Recently, it has been suggested that fetal and early childhood environment might be important for later health status by the concept of “Developmental Origin of Health and Diseases”. Thus, first, we described the trajectories of gestational weight gain (GWG) by using more than 10000 prenatal check-up data. It has been suggested that GWG after the 2nd trimester seemed almost linear and GWG might be increased by maternal smoking during pregnancy. Moreover, we described the trajectory of fetal growth. Fetal growth during the 3rd trimester might be decreased by maternal smoking during pregnancy. Next, the effect of maternal smoking during pregnancy on childhood growth seemed more apparent among children in the 2nd quartile of birth weight. Finally, we established the new cohort study in Gobo city (Wakayama Pref.) to describe the maternal smoking status from pregnancy registration to early childhood medical check-ups for their children.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (25 results)

All 2017 2016 2015

All Presentation (25 results) (of which Int'l Joint Research: 12 results,  Invited: 2 results)

  • [Presentation] Factors associated with the difference between estimated fetal weight at the final prenatal check-up and actual birthweight.2017

    • Author(s)
      Kohta SUZUKI, Rei TSUKAHARA, Zentaro YAMAGATA.
    • Organizer
      30th Annual Meeting of the Society for Pediatric and Perinatal Epidemiologic Research (SPER)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Factors associated with the difference between estimated fetal weight at the final prenatal check-up and actual birthweight.2017

    • Author(s)
      Kohta SUZUKI, Rei TSUKAHARA, Zentaro YAMAGATA.
    • Organizer
      Society for Epidemiologic Research (SER) 50th Annual Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Trajectories of maternal blood pressure during pregnancy grouped by pregestational weight status.2017

    • Author(s)
      Kohta SUZUKI, Rei TSUKAHARA, Zentaro YAMAGATA.
    • Organizer
      第21回国際疫学会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The effect of tobacco exposure in utero on foetal growth trajectory.2017

    • Author(s)
      Kohta Suzuki, Rei Tsukahara, Zentaro Yamagata.
    • Organizer
      The 29th Annual Scientific Conference of the International Society of Environmental Epidemiology (ISEE)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 妊娠前の体格別に見た、妊娠中の体重増加と出生体重における妊婦の身長の影響2017

    • Author(s)
      塚原怜, 鈴木孝太, 山縣然太朗
    • Organizer
      第27回日本疫学会学術総会
    • Place of Presentation
      ベルクラシック甲府(甲府市)
    • Related Report
      2016 Research-status Report
  • [Presentation] The effect of maternal smoking during pregnancy on birthweight through maternal weight status before pregnancy and gestational weight gain2016

    • Author(s)
      Kohta Suzuki, Rei Tsukahara, Zentaro Yamagata
    • Organizer
      5th Conference on Prenatal Programming and Toxicity (PPTOX V: 第5回妊娠前・胎生期・小児期における環境と発育・健康影響に関する国際会議)
    • Place of Presentation
      北九州国際会議場(北九州市)
    • Year and Date
      2016-11-14
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Trajectories of prenatal weight gain among low birthweight and preterm birth infants: A multi-level analysis2016

    • Author(s)
      Kohta Suzuki, Rei Tsukahara, Zentaro Yamagata
    • Organizer
      The 2016 Epidemiology Congress of the Americas
    • Place of Presentation
      Miami, Florida, USA
    • Year and Date
      2016-06-21
    • Related Report
      2015 Research-status Report
  • [Presentation] Effect of maternal smoking during pregnancy on childhood growth by quartile of birth weight using multilevel analysis2016

    • Author(s)
      Kohta Suzuki, Miri Sato, Sonoko Mizorogi, Ryoji Shinohara, Zentaro Yamagata
    • Organizer
      The 2016 Epidemiology Congress of the Americas
    • Place of Presentation
      Miami, Florida, USA
    • Year and Date
      2016-06-21
    • Related Report
      2015 Research-status Report
  • [Presentation] Longitudinal analyses of childhood growth: Evidence from public health activity2016

    • Author(s)
      Kohta Suzuki
    • Organizer
      Joint Japan-New Zealand DOHaD Researchers Seminar
    • Place of Presentation
      Auckland, New Zealand
    • Year and Date
      2016-02-02
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Introduction of nationwide cohort studies in Japan2016

    • Author(s)
      Kohta Suzuki
    • Organizer
      Joint Japan-New Zealand DOHaD Researchers Seminar
    • Place of Presentation
      Auckland, New Zealand
    • Year and Date
      2016-02-02
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Prenatal maternal weight gain trajectories grouped by pregetational weight status2016

    • Author(s)
      Kohta Suzuki, Rei Tsukahara, Zentaro Yamagata
    • Organizer
      第26回日本疫学会学術総会
    • Place of Presentation
      米子コンベンションセンター(鳥取県米子市)
    • Year and Date
      2016-01-21
    • Related Report
      2015 Research-status Report
  • [Presentation] 妊娠中の喫煙と体重増加の関連および、それらが出生体重に与える影響の、妊娠前の体格による検討2016

    • Author(s)
      塚原怜,鈴木孝太,山縣然太朗
    • Organizer
      第26回日本疫学会学術総会
    • Place of Presentation
      米子コンベンションセンター(鳥取県米子市)
    • Year and Date
      2016-01-21
    • Related Report
      2015 Research-status Report
  • [Presentation] Developmental origins of health and disease(DOHaD) cohort studies and interventions - Perinatal and pediatric epidemiological evidence about Developmental Origins of Health and Disease(DOHaD) from clinical and community settings.2016

    • Author(s)
      Kohta Suzuki
    • Organizer
      Conference of International Society for Environmental Epidemiology and International Society of Exposure Science - Asia Chapter 2016(ISEE-ISES AC2016)
    • Place of Presentation
      Hokkaido University Conference Hall
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effect of maternal smoking during pregnancy on childhood growth by quartile of birth weight using multilevel analysis2016

    • Author(s)
      Kohta Suzuki, Miri Sato, Sonoko Mizorogi, Ryoji Shinohara, Zentaro Yamagata
    • Organizer
      2016 Epidemiology Congress of the Americas meeting
    • Place of Presentation
      Hyatt Regency Miami
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Trajectories of prenatal weight gain among low birthweight and preterm birth infants: A multi-level analysis2016

    • Author(s)
      Kohta Suzuki, Rei Tsukahara, Zentaro Yamagata
    • Organizer
      2016 Epidemiology Congress of the Americas meeting
    • Place of Presentation
      Hyatt Regency Miami
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effect of maternal smoking during pregnancy on childhood growth by quartile of birth weight using multilevel analysis2016

    • Author(s)
      Kohta Suzuki, Miri Sato, Sonoko Mizorogi, Ryoji Shinohara, Zentaro Yamagata
    • Organizer
      29th Annual Meeting of the Society for Pediatric and Perinatal Epidemiologic Research (SPER)
    • Place of Presentation
      Hyatt Regency Miami
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Trajectories of prenatal weight gain among low birthweight and preterm birth infants: A multi-level analysis2016

    • Author(s)
      Kohta Suzuki, Rei Tsukahara, Zentaro Yamagata
    • Organizer
      29th Annual Meeting of the Society for Pediatric and Perinatal Epidemiologic Research (SPER)
    • Place of Presentation
      Hyatt Regency Miami
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 妊娠前の体格別に見た、分娩後の体重減少に関連する要因の検討2016

    • Author(s)
      塚原怜, 鈴木孝太, 山縣然太朗
    • Organizer
      第75回日本公衆衛生学会総会
    • Place of Presentation
      グランフロント大阪(大阪市)
    • Related Report
      2016 Research-status Report
  • [Presentation] 喫煙対策を中心とした健康づくりに向けて ~和歌山県御坊市の取り組み~2016

    • Author(s)
      上かおる, 川合さとみ, 南ふみ, 中山真美子, 津村千賀, 原出君枝, 北野尚美, 鈴木孝太
    • Organizer
      第75回日本公衆衛生学会総会
    • Place of Presentation
      グランフロント大阪(大阪市)
    • Related Report
      2016 Research-status Report
  • [Presentation] 地域の母子保健情報の電子化による、 妊娠中の喫煙が出生体重に与える影響の検討2016

    • Author(s)
      鈴木孝太, 北野尚美, 南ふみ, 中山真美子, 津村千賀, 原出君枝, 川合さとみ, 上かおる, 山縣然太朗
    • Organizer
      第75回日本公衆衛生学会総会
    • Place of Presentation
      グランフロント大阪(大阪市)
    • Related Report
      2016 Research-status Report
  • [Presentation] 妊娠中の体重増加に関連する要因と、それらが出生体重に与える影響の検討2015

    • Author(s)
      鈴木孝太,塚原怜,山縣然太朗
    • Organizer
      第74回日本公衆衛生学会総会
    • Place of Presentation
      長崎ブリックホール、長崎新聞文化ホール他(長崎県長崎市)
    • Year and Date
      2015-11-04
    • Related Report
      2015 Research-status Report
  • [Presentation] 妊娠初期、中期、後期での体重増加に関連する詳細な検討2015

    • Author(s)
      塚原怜,鈴木孝太,山縣然太朗
    • Organizer
      第74回日本公衆衛生学会総会
    • Place of Presentation
      長崎ブリックホール、長崎新聞文化ホール他(長崎県長崎市)
    • Year and Date
      2015-11-04
    • Related Report
      2015 Research-status Report
  • [Presentation] 自治体における母子保健情報の電子データ化と、それに伴う課題の検討2015

    • Author(s)
      津村千賀,北野尚美,鈴木孝太,原出君枝,戸根弘貴,南ふみ,中山真美子,小田ひろみ,川合さとみ,上かおる,山縣然太朗
    • Organizer
      第74回日本公衆衛生学会総会
    • Place of Presentation
      長崎ブリックホール、長崎新聞文化ホール他(長崎県長崎市)
    • Year and Date
      2015-11-04
    • Related Report
      2015 Research-status Report
  • [Presentation] 幼児の生活習慣についてのアンケート結果から抽出された地域の課題の検討2015

    • Author(s)
      原出君枝,北野尚美,鈴木孝太,南ふみ,中山真美子,戸根弘貴,津村千賀,小田ひろみ,川合さとみ,上かおる,山縣然太朗
    • Organizer
      第74回日本公衆衛生学会総会
    • Place of Presentation
      長崎ブリックホール、長崎新聞文化ホール他(長崎県長崎市)
    • Year and Date
      2015-11-04
    • Related Report
      2015 Research-status Report
  • [Presentation] 地域母子保健情報に基づく妊娠・育児中の女性における喫煙状況の縦断的検討2015

    • Author(s)
      上田勝也,北野尚美,鈴木孝太,南ふみ,戸根弘貴,中山真美子,津村千賀,原出君枝,小田ひろみ,川合さとみ,上かおる,西岡倫代,形部裕昭,松本政信,山縣然太朗
    • Organizer
      第74回日本公衆衛生学会総会
    • Place of Presentation
      長崎ブリックホール、長崎新聞文化ホール他(長崎県長崎市)
    • Year and Date
      2015-11-04
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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