Complex energy absorption process analysis by lipidomics
Project/Area Number |
15K09401
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Metabolomics
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Research Institution | Tokyo University of Pharmacy and Life Science |
Principal Investigator |
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Project Period (FY) |
2015-04-01 – 2018-03-31
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Project Status |
Completed (Fiscal Year 2017)
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Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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Keywords | エネルギー・糖質代謝異常 / 膜輸送と輸送タンパク質 / リピドミクス |
Outline of Final Research Achievements |
Among omics methods for the quantification/qualification of biological substances, this study is oriented to clarify the mechanisms for the intestinal energy absorption by lipidomics. By selecting nineteen types of lipid as analytes, a new lipidomics method was developed by liquid chromatography ion-trap time-of-flight mass spectrometry (LC-IT-TOF-MS). Real sample analysis showed that linoleic acid, lysophosphatidylcholines, phosphatidylcholines and triacylglycerols in enteral nutrition Twinline were detected by LC-IT-TOF-MS.
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Report
(4 results)
Research Products
(9 results)
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[Journal Article] Determination of serum brassicasterol in spontaneously hypertensive rats stroke-prone fed a high-ergosterol diet by ultra performance liquid chromatography.2016
Author(s)
Ohtsubo, T., Kageyama, R., Koseki, Y., Hagi, J., Kotani, A., Yamamoto, K., Kusu, F., Miura, T., Hakamata, H.
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Journal Title
Eur. J. Lipid Sci. Technol.
Volume: 118
Issue: 7
Pages: 1074-1083
DOI
Related Report
Peer Reviewed
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