Specific differentiation mechanisms of visceral adipogenic cells

Research Project

Project/Area Number	15K09413
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Metabolomics
Research Institution	Tokyo Institute of Technology (2016-2017) Osaka University (2015)
Principal Investigator	Yugo Miyata 東京工業大学, バイオ研究基盤支援総合センター, 研究員 (70623453)
Co-Investigator(Kenkyū-buntansha)	大月道夫大阪大学, 医学系研究科, 講師 (00403056) 福原淳範大阪大学, 医学系研究科, 寄附講座准教授 (00437328) 下村伊一郎大阪大学, 医学系研究科, 教授 (60346145) 小林祥子大阪大学, 医学系研究科, 寄附講座助教 (80649111)
Project Period (FY)	2015-04-01 – 2018-03-31
Project Status	Completed (Fiscal Year 2017)
Budget Amount *help	¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000) Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000) Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords	メタボリックシンドローム / 内臓脂肪
Outline of Final Research Achievements	A large number of papers have shown that fat accumulation and the dysfunction of visceral adipose tissue cause abnormalities in whole body metabolic homeostasis. Recently, we developed a practical in vitro culture system for mesenteric adipocytes. Using the system, specific differentiation mechanisms of in vitro mesenteric adipogenic cells was shown.