Chronic inflammation and sarcopenia in radiotherapy for cancer: novel prognosticators over chronological age
Project/Area Number |
15K09992
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Radiation science
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Research Institution | Kyoto University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
中村 晶 京都大学, 医学研究科, 助教 (40708591)
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Project Period (FY) |
2015-04-01 – 2018-03-31
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Project Status |
Completed (Fiscal Year 2017)
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Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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Keywords | サルコペニア / 慢性炎症 / 放射線治療 / がん治療 / 肺癌 / 燃え尽き症候群 |
Outline of Final Research Achievements |
We evaluated relationship of chronic inflammation and sarcopenia with survival outcomes after radiotherapy for cancer. In patients treated with stereotactic body radiotherapy for early stage lung cancer, chronic inflammation and sarcopenia were respectively associated with lung cancer death and non-lung cancer death. Patients with locally-advanced lung cancer with chronic inflammation and lower body mass index had poorer prognosis. The results suggested that chronic inflammation and sarcopenia can be novel prognosticators over chronological age or tumor stage.
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Report
(4 results)
Research Products
(14 results)
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[Presentation] Impact of Inflammation and Sarcopenia on Outcomes after Stereotactic Body Radiotherapy for T1N0M0 Non-Small Cell Lung Cancer2016
Author(s)
Matsuo Y, Nagata Y, Wakabayashi M, Eba J, Ishikura S, Onishi H, Kokubo M, Karasawa K, Shioyama Y, Onimaru R, Hiraoka M
Organizer
IASLC 17th World Conference on Lung Cancer
Place of Presentation
Messe Wien Exhibition & Congress Center, Vienna, Austria
Year and Date
2016-12-04
Related Report
Int'l Joint Research
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