• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Integrated management of atheroembolism during cardiovascular surgery

Research Project

Project/Area Number 15K10231
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Cardiovascular surgery
Research InstitutionHirosaki University

Principal Investigator

FUKUDA IKUO  弘前大学, 医学研究科, 教授 (50344594)

Research Collaborator KOWATARI Ryosuke  
KAWAMURA Tomonori  
AOKI Chikashi  
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordsアテローム性動脈硬化症 / 脳塞栓症 / 心臓外科手術 / 開心術 / アテローム塞栓症 / 大動脈粥状硬化
Outline of Final Research Achievements

Atheroembolism is a major concern for patients undergoing cardiovascular surgery because prevalence of diabetes and obesity is increasing in recent several decades. In aged patients, athrosclerotic change of the aorta may induce embolism of the atheromatous debris in the aortic wall when instrumentation of the aorta is performed. The purpose of this study is to develop less invasive technique to avoid detachment of the debris from the arctic wall during operation.
We developed a less invasive system to connect side branch on the ascending aorta without touching the diseased aorta. This system is consisted of the connecting device and aortic cutter without interruption of the aortic flow during operation. Side-clamp of the aorta is also unnecessary. Therefore, risk of atheromebolism is minimum if this system is used.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (28 results)

All 2018 2017 2016 2015

All Journal Article (13 results) (of which Peer Reviewed: 13 results,  Open Access: 9 results) Presentation (13 results) (of which Int'l Joint Research: 8 results,  Invited: 2 results) Book (2 results)

  • [Journal Article] Matrix Gla protein negatively regulates calcification of human aortic valve interstitial cells isolated from calcified aortic valves2018

    • Author(s)
      Chiyoya Mari、Seya Kazuhiko、Yu Zaiqiang、Daitoku Kazuyuki、Motomura Shigeru、Imaizumi Tadaatsu、Fukuda Ikuo、Furukawa Ken-Ichi
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 136 Issue: 4 Pages: 257-265

    • DOI

      10.1016/j.jphs.2018.03.004

    • NAID

      130007812658

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Management of Pulmonary Thromboembolism Based on Severity and Vulnerability to Thrombolysis2017

    • Author(s)
      Fukuda W, Taniguchi S, Fukuda I, Chiyoya M, Aoki C, Kondo N, Hattori K, Daitoku K, Kowatari R, Minakawa M, Suzuki Y.
    • Journal Title

      Annals of Vascular Diseases

      Volume: 10 Issue: 4 Pages: 371-377

    • DOI

      10.3400/avd.oa.17-00105

    • NAID

      130006282023

    • ISSN
      1881-641X, 1881-6428
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Endovascular "Intimal Flap Septostomy" for Safe Landing of a Stent Graft in an Anastomotic Pseudoaneurysm of Chronic Type B Aortic Dissection.2017

    • Author(s)
      Saito Y, Tani K, Taniguchi S, Fukuda I.
    • Journal Title

      EJCES: European Journal of Vascular Endovascular Surgery

      Volume: 37 Pages: 5-7

    • DOI

      10.1016/j.ejvssr.2017.09.002

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Surgical Embolectomy for Acute Pulmonary Thromboembolism2017

    • Author(s)
      Fukuda I, Daitoku K.
    • Journal Title

      Annals of Vascular Diseases

      Volume: 10 Issue: 2 Pages: 107-114

    • DOI

      10.3400/avd.ra.17-00038

    • NAID

      130006602708

    • ISSN
      1881-641X, 1881-6428
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Rate of Stenotic Bicuspid Aortic Valve Aortic Dilatation After Aortic Valve Replacement, Calculated Using a 3-Dimensional Reconstruction Tool.2017

    • Author(s)
      Hattori K, Fukuda I, Daitoku K, Minakawa M, Itaya H.
    • Journal Title

      Circulation Journal

      Volume: 81 Pages: 1200-1212

    • NAID

      130005859082

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Improved outcomes for ruptured abdominal aortic aneurysms using integrated management imvolving endovascular clamping, endovascular replacement, and ope abdominal decompression.2017

    • Author(s)
      Aoki C, Kondo N, Saito Y, Taniguchi S, Fukuda W, Daitoku K, Fukuda I
    • Journal Title

      Ann Vasc Dis

      Volume: 10 Pages: 22-28

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Surgical management of mycotic aortic aneurysms.2017

    • Author(s)
      Aoki C, Fukuda W, Kondo N, Minakawa M, Taniguchi S, Daitoku K, Fukuda I.
    • Journal Title

      Ann Vasc Dis

      Volume: 10 Pages: 29-35

    • NAID

      130005475937

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] A novel surgical procedure for scimitar syndrome: scimitar vein with right atrium and inferior vena cava wall flap.2016

    • Author(s)
      Kowatari R, Suzuki Y, Daitoku K, Hattori K, Fukuda I.
    • Journal Title

      J Card Surg

      Volume: 10 Issue: 10 Pages: 642-644

    • DOI

      10.1111/jocs.12821

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Numerical simulation of blood flow in femoral perfusion: comparison between side-armed femoral artery perfusion and direct femoral artery perfusion.2016

    • Author(s)
      Kitamura S, Shirota M, Fukuda W, Inamura T, Fukuda I.
    • Journal Title

      J Artif Organs

      Volume: 4 Pages: 336-342

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Direct epicardial assist device using artificial rubber muscle in a swine model of pediatric dilated cardiomyopathy.2015

    • Author(s)
      Saito Y, Suzuki Y, Kondo N, Kowatari R, Daitoku K, Minakawa M, Fukuda I.
    • Journal Title

      International Journal of Artificial Organs

      Volume: 38 Issue: 11 Pages: 588-594

    • DOI

      10.5301/ijao.5000447

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Novel Method of Assessing Ascending Aorta with a Stenotic Bicuspid Aortic Valve.2015

    • Author(s)
      Hattori K, Fukuda I, Daitoku K, Fukuda W, Minakawa M, Suzuki Y.
    • Journal Title

      Journal of Heart Valve Disease

      Volume: 24 Pages: 554-559

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Cardiac supporting device using artificial rubber muscle: preliminary study to active dynamic cardiomyoplasty2015

    • Author(s)
      Saito Y, Suzuki Y, Goto T, Daitoku K, Minakawa M, Fukuda I
    • Journal Title

      Journal of Artificial Organs

      Volume: 18 Pages: 377-381

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Hydrodynamic evaluation of a new dispersive aortic cannula (Stealthflow).2015

    • Author(s)
      Goto T, Inamura T, Shirota M, Fukuda W, Fukuda I, Daitoku K, Minakawa M, Ito K.
    • Journal Title

      Journal of Artificial Organs

      Volume: 18

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Presentation] The interim analysis of the Xarelto post-marketing surveillance in Japanese patients with venous thromboembolism2018

    • Author(s)
      平山篤志、福田幾夫、川杉和夫、小林隆夫、中西宣文、中村真潮、山田典一、武市真希子、岡山豊、砂谷俊行、大橋陽平、坂口俊晃、山本倫行、山中聡
    • Organizer
      第82回日本循環器学会総会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Cerebral vascular disaese is not risk of postoperative cerebral infarction to patients performed aortic valve replacement2018

    • Author(s)
      大徳和之、于在強、皆川正仁、福田幾夫
    • Organizer
      第82回日本循環器学会総会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 高齢者大動脈弁狭窄症に対するSAVRの手術成績と危険因子の検討2018

    • Author(s)
      服部薫、大徳和之、福田幾夫ほか
    • Organizer
      第48回日本心臓血管外科学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 構造破壊を伴う大動脈弁位感染性心内膜炎に対する分類化の試み2018

    • Author(s)
      今村優紀、大徳和之、福田幾夫ほか
    • Organizer
      第48回日本心臓血管外科学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Clinical evaluation of new dispersive aortic cannula2018

    • Author(s)
      Goto T, Fukuda I, et al
    • Organizer
      AmSECT's 56th International Conference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effect of inflow cannulas side-hole number on drainage flow characteristics: flow dynamic analysis using numerical simulation2017

    • Author(s)
      Goto T, Fukuda I et al
    • Organizer
      ESAO and IFA 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Management of acute pulmonary embolism during pregnancy2016

    • Author(s)
      Wakako Fukuda, Ikuo Fukuda, Satoshi Taniguchi
    • Organizer
      9th Conference of the German-Japanese Society of Vascular Surgery
    • Place of Presentation
      Grand Prince Hotel Hiroshima(広島県・広島市)
    • Year and Date
      2016-08-19
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Pulmonary embolectomy in Japan2016

    • Author(s)
      Ikuo Fukuda, Wakako Fukuda, Satoshi Taniguchi
    • Organizer
      9th Conference of the German-Japanese Society of Vascular Surgery
    • Place of Presentation
      Grand Prince Hotel Hiroshima(広島県・広島市)
    • Year and Date
      2016-08-19
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 大動脈弁はなぜ石灰化するのか?ビタミンK依存性マトリックスGlaタンパク質の影響2016

    • Author(s)
      千代谷真理、于在強、瀬谷和彦、大徳和之、古川 賢一、村上学、福田幾夫
    • Organizer
      第46回日本心臓血管外科学会総会
    • Place of Presentation
      名古屋市,名古屋国際会議場
    • Year and Date
      2016-02-15
    • Related Report
      2015 Research-status Report
  • [Presentation] Complicated type B aortic dissectionは血管内治療のみで十分か2016

    • Author(s)
      千代谷真理、福田幾夫
    • Organizer
      第44回日本血管外科学会総会
    • Place of Presentation
      ホテル グランパシフィックLE DAIBA (東京都)
    • Related Report
      2016 Research-status Report
  • [Presentation] Shaggy aortaを伴う胸部下行・胸腹部大動脈瘤の治療2015

    • Author(s)
      福田幾夫
    • Organizer
      第68回日本胸部外科学会総会
    • Place of Presentation
      神戸市, 神戸ポートピアホテル
    • Year and Date
      2015-10-19
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] Retrievable IVC filter. -Which one is more effective and safe-2015

    • Author(s)
      Chiyoya M, Fukuda W, Taniguchi S, Saito Y, Fukuda I
    • Organizer
      UIP Chapter Meeting: Seoul UIP 2015
    • Place of Presentation
      Korea, Seoul
    • Year and Date
      2015-08-28
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Management of acute pulmonary embolism during pregnancy2015

    • Author(s)
      Fukuda I, Fukuda W, Daitoku K, Taniguchi S, Yoshiaki S
    • Organizer
      UIP Chapter Meeting: Seoul UIP 2015
    • Place of Presentation
      Korea, Seoul
    • Year and Date
      2015-08-28
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Book] 心筋保護標準テキストブック2016

    • Author(s)
      上田裕一、山本浩史、福田幾夫
    • Total Pages
      223
    • Publisher
      文光堂
    • Related Report
      2015 Research-status Report
  • [Book] 静脈血栓塞栓症診断・治療マニュアル2015

    • Author(s)
      福田幾夫編集
    • Total Pages
      588
    • Publisher
      医薬ジャーナル社
    • Related Report
      2015 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi