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A study on optimized biomechanical implant prosthetic design based on bone remodeling algorithm using in vivo measured load

Research Project

Project/Area Number 15K11147
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Prosthodontics/ Dental materials science and
Research InstitutionTohoku University

Principal Investigator

Kawata Tetsuo  東北大学, 歯学研究科, 大学院非常勤講師 (80292225)

Co-Investigator(Kenkyū-buntansha) 依田 信裕  東北大学, 歯学研究科, 助教 (20451601)
佐々木 啓一  東北大学, 歯学研究科, 教授 (30178644)
小川 徹  東北大学, 歯学研究科, 准教授 (50372321)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordsインプラント / 生体力学 / 有限要素解析 / 骨リモデリング / 生体内荷重 / 歯科用インプラント / 生体内測定
Outline of Final Research Achievements

This study combines clinical investigation with finite element (FE) analysis to explore the effects of buccal bone thickness (BBT) on the morphological changes of buccal bone. One patient who had undergone an implant treatment in the anterior maxilla and experienced the buccal bone resorption on the implant was studied. Morphological changes of the bone were measured through a series of CT scans. A 3D heterogeneous nonlinear FE model was constructed based on the CT images, and the in-vivo BBT changes are correlated to the mechanical stimuli. The anterior incisory bone region of this model was then varied systematically to simulate different BBTs. Significant changes in BBTs were observed clinically. The pattern of bone resorption fell into a strong correlation with the distribution of mechanical stimuli onsite. This study revealed that the initial BBT can significantly affect mechanical responses, which consequentially determines the bone remodeling process.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (18 results)

All 2017 2016 2015 Other

All Int'l Joint Research (3 results) Journal Article (8 results) (of which Int'l Joint Research: 6 results,  Peer Reviewed: 7 results,  Open Access: 3 results,  Acknowledgement Compliant: 2 results) Presentation (7 results) (of which Int'l Joint Research: 3 results,  Invited: 1 results)

  • [Int'l Joint Research] シドニー大学(オーストラリア)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] The University of Sydney(Australia)

    • Related Report
      2016 Research-status Report
  • [Int'l Joint Research] The University of Sydney(Australia)

    • Related Report
      2015 Research-status Report
  • [Journal Article] Identification of dynamic load for prosthetic structures2017

    • Author(s)
      Zhang. D., Han. X., Zhang. Z., Liu. J., Jiang. C., Yoda. N., Meng. X., Li. Q
    • Journal Title

      Int J Numer Method Biomed Eng

      Volume: 印刷中 Issue: 12

    • DOI

      10.1002/cnm.2889

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Bone morphological effects on post-implantation remodeling of maxillary anterior buccal bone: A clinical and biomechanical study2017

    • Author(s)
      Yoda. N., Zheng. K., Chen. J., Li. W., Sasaki. K., Swain. M., Li. Q.
    • Journal Title

      Journal of Prosthodontic Research

      Volume: 61 Issue: 4 Pages: 393-402

    • DOI

      10.1016/j.jpor.2016.12.010

    • NAID

      130006198479

    • ISSN
      1883-1958, 1883-9207
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effect of Configurations of Implants supporting a Four-unit Fixed Partial Denture on Loading Distribution2017

    • Author(s)
      Yoda. N., Sun. J., Matsudate. Y., Hong. G., Kawata. K., Sasaki. K
    • Journal Title

      Int J Prosthodont

      Volume: 30 Pages: 68-70

    • DOI

      10.11607/ijp.5033

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Simulation of multi-stage non-linear bone remodeling induced by fixed partial dentures of different configurations: a comparative clinical and numerical study2017

    • Author(s)
      Liao. Z., Yoda. N., Chen. J., Zheng. K., Sasaki. K., Swain. M., Li. Q.
    • Journal Title

      Biomech Model Mechanobiol

      Volume: 16 Pages: 411-423

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Effects of food texture on three-dimensional loads on implants during mastication based on in vivo measurements2016

    • Author(s)
      Yoda N, Ogawa T, Gunji Y, Vanegas JR, Kawata T, Sasaki K.
    • Journal Title

      Implant Dentistry

      Volume: 25 Issue: 4 Pages: 515-519

    • DOI

      10.1097/id.0000000000000443

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Role of implant configurations supporting three-unit fixed partial denture on mandibular bone response: biological-data-based finite element study.2016

    • Author(s)
      Yoda N, Liao Z, Chen J, Sasaki K, Swain M, Li Q.
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 43 Issue: 9 Pages: 692-701

    • DOI

      10.1111/joor.12411

    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] An In Vivo Study on Loading Distribution in Different Implant Configurations for Supporting Fixed Partial Denture2016

    • Author(s)
      Kobari H, Yoda N, Chen J, Kawata T, Sasaki K
    • Journal Title

      The International Journal of Oral & Maxillofacial Implants

      Volume: 印刷中

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effect of Configurations of Implants supporting a Four-unit Fixed Partial Denture on Loading Distribution2016

    • Author(s)
      Yoda N, Sun J, Matsudate Y, Hong G, Kawata K, Sasaki K
    • Journal Title

      International Journal of Prosthodontics

      Volume: 印刷中

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] Investigation of Bone Morphological Change in Maxillary Anterior Buccal Bone on Implant: a Clinical and Numerical Study2017

    • Author(s)
      Yoda N, Zheng K, Chen J, Swain M, Li Q, Sasaki K
    • Organizer
      Dentsply Implants World Summit Tour 2017
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2017-02-18
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 生体ベース非線形骨改造アルゴリズムに基づくインプラント周囲の経年的骨密度変化解析2017

    • Author(s)
      依田信裕、小針啓司、 松舘芳樹、 川田哲男、佐々木啓一
    • Organizer
      日本補綴歯学会第126回学術大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 有限要素解析を用いたインプラント機能時の動的力学挙動に関する研究2017

    • Author(s)
      佐藤愛美加、重光竜二、水戸武彦、依田信裕、佐々木啓一
    • Organizer
      第47回日本口腔インプラント学会学術大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Biomechanical effect on bone remodeling in a mandibular reconstruction case using fibula free flap2017

    • Author(s)
      Yoda N, Chen J, Zhang K, Koyama S, Sato N, Kiyama T, Swain M, Li Q, Sasaki K
    • Organizer
      The 4th joint meeting of the ISMR and the AAMP
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] バイオメカニクス・メカノバイオロジーの観点から欠損歯科補綴を考える2016

    • Author(s)
      依田 信裕
    • Organizer
      第2回 補綴歯科臨床研鑽会 プロソ'16
    • Place of Presentation
      ベルサール新宿,東京
    • Year and Date
      2016-12-10
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] Biomechanical Bone Responses by Mandibular Reconstruction with Fibula Free Flap2016

    • Author(s)
      Yoda N, Chen J, Zhang K, Liao Z, Koyama S, Sato N, Li W, Sasaki K, Swain M, Li Q
    • Organizer
      11th Biennial Meeting of the ISMR
    • Place of Presentation
      Belgrade, Serbia
    • Year and Date
      2016-05-04
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] The biomechanical responses of mandibular bone installed with implant-supported dental bridges - a computational mechanics study2015

    • Author(s)
      Yoda N, Liao Z, Chen J, Sasaki K, Li Q
    • Organizer
      The 2nd Australasian Conference on Computational Mechanics
    • Place of Presentation
      Brisbane, Australia
    • Year and Date
      2015-11-30
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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