| Project/Area Number |
15K11167
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Prosthodontics/ Dental materials science and
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| Research Institution | Nagasaki University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
渡邊 郁哉 長崎大学, 医歯薬学総合研究科(歯学系), 教授 (00274671)
白石 孝信 長崎大学, 医歯薬学総合研究科(歯学系), 准教授 (10150468)
尾立 哲郎 長崎大学, 病院(歯学系), 講師 (70513167)
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| Project Period (FY) |
2015-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | Zirconia / Zinc phosphate / Calcium phosphate / Calcium Treatment / Bioactive Coating / Zinc Phosphate |
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| Outline of Final Research Achievements |
The purpose of this study was the preparation of a firmly adhered calcium phosphate coating layer on the zinc phosphatized zirconia to be used as a dental implant. Yttria doped ZrO2 (zirconia) plates were placed in an acidic zinc phosphatizing solution in a Teflon vessel covered by a stainless jacket for hydrothermal treatment. The zinc phosphate coating layer was made by hydrothermal treatment in an acidic zinc phosphate solution. Then the zinc phosphatized zirconia substrate was hydrothermally treated by calcium acetate solutions to convert the surface structure to calcium phosphate. In this study the firmly adhered zinc phosphate coating and then calcium phosphate coating were prepared successfully. Surface morphology, elemental analysis, phase transformation, biaxial flexural strength, coating layer adhesion and surface cell response were investigated in this study.
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| Academic Significance and Societal Importance of the Research Achievements |
本研究で創製された新しいHAによるジルコニアのコーティング手法は画期的なインプラント材への応用が可能であると考えられる。歯科インプラント臨床への貢献が期待される。また、本コーティング法は整形外科インプラント等にも応用可能であると考えられるため、歯学インプラント材のみならず歯学・医学を始めとする多方面での新規な材料開発への展開が期待される。
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