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Development of new composite resin with greater mechanical strength by optimizing structure using in silico analysis

Research Project

Project/Area Number 15K11195
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Prosthodontics/ Dental materials science and
Research InstitutionOsaka University

Principal Investigator

YAMAGUCHI SATOSHI  大阪大学, 歯学研究科, 准教授 (30397773)

Co-Investigator(Kenkyū-buntansha) 今里 聡  大阪大学, 歯学研究科, 教授 (80243244)
Research Collaborator INOUE SAYURI  大阪大学
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords歯学 / 歯科材料 / コンポジットレジン / 有限要素解析 / マルチスケール解析 / 長期耐久性 / シランカップリング / CAD/CAM / 加速疲労試験 / 均質化解析 / 歯科用修復材料 / バイオメカニクス / 有限要素法 / 構造最適化
Outline of Final Research Achievements

In this study, a mechanism to improve the mechanical strength of composite resin (CR) was successfully elucidated by in silico prediction of relevance between parameters (a type of fillers, sizes, contents, and geometric layouts) and the mechanical strength. Furthermore, optimized these parameters demonstrated that the possibility to develop new CR with greater mechanical strength and higher longevity.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (19 results)

All 2018 2017 2016 2015 Other

All Int'l Joint Research (2 results) Journal Article (5 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 5 results,  Acknowledgement Compliant: 3 results) Presentation (11 results) (of which Int'l Joint Research: 6 results,  Invited: 1 results) Remarks (1 results)

  • [Int'l Joint Research] New York University College of Dentistry(米国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] New York University College of Dentistry(米国)

    • Related Report
      2016 Research-status Report
  • [Journal Article] <i>In vitro</i>/<i>in silico</i> investigation of failure criteria to predict flexural strength of composite resins2018

    • Author(s)
      Yamaguchi S, Mehdawi IM, Sakai T, Abe T, Inoue S, Imazato S
    • Journal Title

      Dental Materials Journal

      Volume: 37 Issue: 1 Pages: 152-156

    • DOI

      10.4012/dmj.2017-084

    • NAID

      130006322117

    • ISSN
      0287-4547, 1881-1361
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] <i>In vitro</i> fatigue tests and <i>in silico</i> finite element analysis of dental implants with different fixture/abutment joint types using computer-aided design models2018

    • Author(s)
      Yamaguchi S, Yamanishi Y, Machado LS, Matsumoto S, Tovar N, Coelho PG, Thompson VP, Imazato S
    • Journal Title

      Journal of Prosthodontic Research

      Volume: 62 Issue: 1 Pages: 24-30

    • DOI

      10.1016/j.jpor.2017.03.006

    • NAID

      130006619315

    • ISSN
      1883-1958, 1883-9207
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Multi-scale analysis of the effect of nano-filler particle diameter on the physical properties of CAD/CAM composite resin blocks2017

    • Author(s)
      Yamaguchi S*, Inoue S, Sakai T, Abe T, Kitagawa H, Imazato S
    • Journal Title

      Computer Methods in Biomechanics and Biomedical Engineering

      Volume: 20 Issue: 7 Pages: 714-719

    • DOI

      10.1080/10255842.2017.1293664

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] In silico analysis of the biomechanical stability of commercially pure Ti and Ti-15Mo plates for the treatment of mandibular angle fracture2017

    • Author(s)
      Yamaguchi S*, Anchieta RB, Guastaldi FP, Tovar N, Tawara D, Imazato S, Coelho PG
    • Journal Title

      Journal of Oral and Maxillofacial Surgery

      Volume: 印刷中 Issue: 5 Pages: 1004.e1-1004.e9

    • DOI

      10.1016/j.joms.2016.12.043

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Influence of implant length and diameter, bicortical anchorage, and sinus augmentation on bone stress distribution: three-dimensional finite element analysis2016

    • Author(s)
      Moriwaki H, Yamaguchi S*, Nakano T, Yamanishi Y, Imazato S, Yatani H
    • Journal Title

      The International Journal of Oral & Maxillofacial Implants

      Volume: 31 Issue: 4 Pages: e84-e91

    • DOI

      10.11607/jomi.4217

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] シランカップリングの割合がCAD/CAM コンポジットレジンブロックの圧縮強さに及ぼす影響についてのin silico解析2017

    • Author(s)
      加島佳奈,山口 哲,今里 聡
    • Organizer
      第70回日本歯科理工学会学術講演会
    • Related Report
      2017 Annual Research Report
  • [Presentation] CAD/CAMコンポジットレジン冠の破断荷重と長期耐久性評価2017

    • Author(s)
      山口 哲,可児廉志郎,河上和馬,井上小百合,騎馬和歌子,今里 聡
    • Organizer
      第70回日本歯科理工学会学術講演会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Fatigue resistance of dental implants with different fixture-abutment connections2017

    • Author(s)
      Yamaguchi S, Yamanishi Y, Machado LS, Matsumoto S, Tovar N, Coelho PG, Thompson VP, Imazato S
    • Organizer
      95 General Session & Exhibition of the IADR
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effect of experimental blue and violet LCUs on physical properties of a CQ/TPO resin composite2017

    • Author(s)
      Sampaio CS, Atria J, Rueggeberg FA, Yamaguchi S, Giannini M, Coelho PG, Hirata R, Puppin-Rontani RM
    • Organizer
      95th General Session & Exhibition of the IADR
    • Place of Presentation
      San Francisco (USA)
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Homogenization-analysis of influences of filler-shapes on physical properties of composites2016

    • Author(s)
      Yamaguchi S, Abe T, Sakai T, Imazato S
    • Organizer
      94th General Session & Exhibition of the IADR
    • Place of Presentation
      Seoul (Korea)
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Influence of constant strain on elastic modulus of thermoplastic orthodontic materials2016

    • Author(s)
      Inoue S, Yamaguchi S, Uyama H, Yamashiro T, Imazato S
    • Organizer
      International Dental Materials Congress 2016
    • Place of Presentation
      Bali (Indonesia)
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] In silico biomechanics research of dental materials, tooth, and bone2015

    • Author(s)
      Yamaguchi S
    • Organizer
      Seoul National University Dental Research Institute Seminar(招待講演)
    • Place of Presentation
      Seoul (Korea)
    • Year and Date
      2015-12-08
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] In silico evaluation of mechanical properties of composite resins using high-resolution nano-CT images2015

    • Author(s)
      Sakai T, Abe T, Yamaguchi S, Imazato S
    • Organizer
      The 63rd Annual Meeting of Japanese Association for Dental Research
    • Place of Presentation
      福岡県,福岡国際会議場
    • Year and Date
      2015-10-30
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] In silico multi-scale analysis of composite resin block for CAD/CAM2015

    • Author(s)
      Yamaguchi S, Inoue S, Sakai T, Abe T, Imazato S
    • Organizer
      The Academy of Dental Materials 2015 Annual Meeting
    • Place of Presentation
      Hawaii (USA)
    • Year and Date
      2015-10-07
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] CAD/CAM用コンポジットレジンの機械的特性~マルチスケール解析による圧縮強度の評価~2015

    • Author(s)
      山口 哲,井上小百合,堺 貴彦,安部友大,今里 聡
    • Organizer
      第66回日本歯科理工学会学術講演会
    • Place of Presentation
      東京都,タワーホール船堀
    • Year and Date
      2015-10-03
    • Related Report
      2015 Research-status Report
  • [Presentation] マルチスケール解析に基づく高解像度ナノCT画像を用いたコンポジットレジンの機械的性質の評価2015

    • Author(s)
      堺 貴彦,安部友大,井上小百合,山口 哲,今里 聡
    • Organizer
      日本歯科理工学会近畿・中四国地方会夏期セミナー
    • Place of Presentation
      大阪府,大阪歯科大学 創立百周年記念館
    • Year and Date
      2015-08-22
    • Related Report
      2015 Research-status Report
  • [Remarks] 歯科理工学教室(Publications)

    • URL

      http://web.dent.osaka-u.ac.jp/~techno/publications.html

    • Related Report
      2017 Annual Research Report 2016 Research-status Report 2015 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2022-06-07  

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