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Investigation of effectiveness that surgical orthodontics for orofacial hypogrowth affect sleep apnea and gastroesophageal reflux

Research Project

Project/Area Number 15K11351
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthodontics/Pediatric dentistry
Research InstitutionKagoshima University

Principal Investigator

Kuninori Takaharu  鹿児島大学, 医歯学域歯学系, 助教 (00626666)

Co-Investigator(Kenkyū-buntansha) 宮脇 正一  鹿児島大学, 医歯学域歯学系, 教授 (80295807)
友成 博  鶴見大学, 歯学部, 教授 (70398288)
大牟禮 治人  鹿児島大学, 医歯学総合研究科, 客員研究員 (00404484)
永山 邦宏  鹿児島大学, 医歯学総合研究科, 客員研究員 (60583458)
高田 寛子  鹿児島大学, 医歯学総合研究科, 客員研究員 (80634229)
八木 孝和  鹿児島大学, 医歯学域歯学系, 講師 (10346166)
Project Period (FY) 2015-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords外科的矯正治療 / 睡眠時無呼吸 / 胃食道逆流 / 上顎劣成長 / 下顎劣成長
Outline of Final Research Achievements

The purpose of this study is to investigate of effectiveness that surgical orthodontics for orofacial hypogrowth affect sleep apnea and gastroesophageal reflux. However, in addition to rarely planning an upper/lower jawbone advancement for a patient with maxillary or mandibular deficiency, and largeness of the physical burden of polysomnography or endoscopic examination, there were difficulties in securing subjects.
Therefore, to investigate transversely between nasal patency/air flow of nasal cavity and maxillofacial morphology, we performed rhinomanometry and acoustic rhinometry for 50 subjects since 2017. However, there was no relationship between tem.

Academic Significance and Societal Importance of the Research Achievements

現在、OSAに対して下顎を前方誘導する可撤式の口腔内装置や、GERDに対して薬物療法などの対症療法が行われている。外科的矯正治療が上下顎骨の劣成長に起因する咽頭気道の狭窄を改善することで、睡眠呼吸障害や上部消化管疾患に対する治療効果が解明されれば、呼吸器内科及び消化器内科との隣接領域において歯科が主体となって行う根本療法が将来期待できると考え、鼻腔の開存性や通気性と顎顔面形態との関連について合計50名に対して検証したが、それらの間に関連は認められなかった。

Report

(5 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (3 results)

All 2017

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (2 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Micrognathia with temporomandibular joint ankylosis and obstructive sleep apnea treated with mandibular distraction osteogenesis using skeletal anchorage: a case report2017

    • Author(s)
      Tomonari Hiroshi、Takada Hiroko、Hamada Tomofumi、Kwon Sangho、Sugiura Tsuyoshi、Miyawaki Shouichi
    • Journal Title

      Head & Face Medicine

      Volume: 13 Issue: 1 Pages: 20-20

    • DOI

      10.1186/s13005-017-0150-4

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Factors related to the failure of miniscrew implants and the development of an auxiliary appliance to increase the retention force as its solution.2017

    • Author(s)
      Miyawaki S
    • Organizer
      World implant Orthodontic Conference 2017 (9th WIOC).
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] A possibility of a new physiological significance of sleep bruxism.2017

    • Author(s)
      Miyawaki S
    • Organizer
      31st IADR-SEA 28th SEAADE.
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research

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Published: 2015-04-16   Modified: 2020-03-30  

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