| Project/Area Number |
15K11415
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Okayama University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
森田 学 岡山大学, 医歯薬学総合研究科, 教授 (40157904)
江國 大輔 岡山大学, 医歯薬学総合研究科, 准教授 (70346443)
友藤 孝明 朝日大学, 歯学部, 教授 (80335629)
水谷 慎介 岡山大学, 医歯薬学総合研究科, 助教 (90643312)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
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| Keywords | 歯肉炎 / スクリーニング / 唾液LDH / 口腔細菌叢 / 次世代シーケンサー / MMP-9 |
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| Outline of Final Research Achievements |
We investigated the usefulness of non-invasive screening for gingivitis using saliva. Among university students, we investigated the association between gingivitis and lactate dehydrogenase level in saliva in a cross-sectional study and the association between oral microflora in saliva and progression of gingivitis in a longitudinal study. The level of lactate dehydrogenase in saliva was significantly associated with gingivitis. However, there was no significant association between oral microflora and progression of gingivitis in university students.
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