Role of apelin on mechanisms to improve state of periodontitis by physical activity and its application to preventive dentistry
| Project/Area Number |
15K11423
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Kyushu Dental College |
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Principal Investigator |
Akifusa Sumio 九州歯科大学, 歯学部, 教授 (40295861)
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| Co-Investigator(Kenkyū-buntansha) |
有吉 渉 九州歯科大学, 歯学部, 准教授 (40405551)
臼井 通彦 九州歯科大学, 歯学部, 准教授 (10453630)
沖永 敏則 九州歯科大学, 歯学部, 講師 (60582773)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 身体活動 / apelin / 高齢者 / 栄養 / 菌叢解析 / 口腔ケア / 歯周疾患 / 最大呼気量 / 血管流路 / サイトカイン |
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| Outline of Final Research Achievements |
We investigated relationship between physical activity and oral health status in older adults by follow-up survey. The cohort of older adults with dysphagia at baseline deteriorated physical activity and nutritional status at 1 years later, comparing with the cohort having normal swallowing function. Mortality risk of older adults with > 9 remained tooth and dysphagia was 2.89-fold higher than that of older adults > 10 remained tooth and with normal swallowing function. Next we elucidated the peak expiratory flow (PEF), having closing relation with physical activity, in older adults who were intervened with oral care with tongue cleaning. The PEFs of older adults intervened by oral care with tongue cleaning was significantly higher than of those without tongue cleaning. Unfortunately, we could get no significant data on relationship between amounts of blood apelin and PEF.
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Report
(4 results)
Research Products
(22 results)
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[Journal Article] Tooth loss, swallowing dysfunction and mortality in Japanese older adults receiving home care services2017
Author(s)
Furuta, M., Takeuchi, K., Adachi, M., Kinoshita, T., Eshima, N., Akifusa, S., Kikutani, T., Yamashita, Y.
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Journal Title
Geriatrics & Gerontology International
Volume: -
Issue: 6
Pages: 873-880
DOI
Related Report
Peer Reviewed
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[Journal Article] Bacterial diversity in saliva and oral health-related conditions: the Hisayama Study.2016
Author(s)
Takeshita T, Kageyama S, Furuta M, Tsuboi H, Takeuchi K, Shibata Y, Shimazaki Y, Akifusa S, Ninomiya T, Kiyohara Y, Yamashita Y.
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Journal Title
Science Reorts
Volume: 6
Issue: 1
Pages: 1-11
DOI
Related Report
Peer Reviewed / Open Access
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