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Longitudinal Study of the Association between Breastfeeding and neuromotor Development in Low Birth Weight Infants

Research Project

Project/Area Number 15K11716
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Lifelong developmental nursing
Research InstitutionWakayama Medical University (2018-2019)
Yamanashi Prefectural University (2015-2017)

Principal Investigator

Inoue Miyuki  和歌山県立医科大学, 保健看護学部, 教授 (80347351)

Co-Investigator(Kenkyū-buntansha) 丸山 憲一 (丸山憲一)  群馬県衛生環境研究所, 研究企画係, 研究員 (80728741)
Project Period (FY) 2015-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords超・極低出生体重児 / 神経運動発達 / 母乳 / 母親の学歴 / 新生児看護 / 極低出生体重児 / 母乳栄養 / 子育て支援 / 発達 / NICU / 低出生体重児 / 母親の教育歴 / 家庭環境 / 乳房のセルフケア / 超低出生体重児 / 壊死性腸炎 / 認知発達
Outline of Final Research Achievements

The aim of this study was to clarify the longitudinal relationship between breast-feeding during NICU admission and neuromotor development at 18 months and 3 years of age in low-birth-weight infants weighing less than 1500 g at birth.
The results showed that "No artificial ventilation (intubation)" "High Breastmilk Percentage of Total Enteral Nutrition during NICU Hospitalization" and "Enteral nutrition 100 ml/kg/day" were associated with development test values at 18 months. Associated at age 3 years was "be highly educated by one's mother". These results indicate that at 18 months of age, development was influenced by breast-feeding and the physical condition of the newborn, but at 36 months of age, when family life became longer, it was influenced by the higher education of the mother, who was in a human rearing environment.

Academic Significance and Societal Importance of the Research Achievements

本研究から、子どもの発達のためには、新生児期の身体的な状態だけではなく、母乳栄養、母親の学歴などの養育環境が子どもの発達に影響していることが示唆された。本研究の結果は、出生体重1500g未満の低出生体重児の成長・発達を促進のために母乳栄養は重要となり、母乳栄養を促進するためのエビデンスとなる。また、家庭での生活が長くなると「母親の教育歴が高い」ことが子どもの発達に影響しており、家庭内での母親の関り方により子どもの発達が促進できると考えられる。

Report

(6 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (17 results)

All 2020 2019 2018 2017 2016

All Journal Article (5 results) (of which Peer Reviewed: 4 results,  Open Access: 1 results) Presentation (12 results) (of which Int'l Joint Research: 3 results)

  • [Journal Article] 小児病院の周産期センター化が極低出生体重児の長期予後に及ぼす影響:第1報 3歳時の新版K式発達検査の結果についての検討2020

    • Author(s)
      丸山憲一
    • Journal Title

      小児科臨床

      Volume: 73 Pages: 509-513

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 小児病院の周産期センター化が極低出生体重児の長期予後に及ぼす影響:第1報 3歳時の新版K式発達検査の結果についての検討2019

    • Author(s)
      丸山憲一
    • Journal Title

      小児科臨床

      Volume: 72 Pages: 1689-1693

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 早産児、低出生体重児への母乳投与:第2報 新生児集中治療室退院後1カ月における検討2018

    • Author(s)
      丸山憲一、小泉亜矢、井上文孝、福田一代、市之宮健二、宮川陽一
    • Journal Title

      日本新生児成育医学会雑誌

      Volume: 30 Pages: 77-83

    • Related Report
      2018 Research-status Report
  • [Journal Article] Effects of breast milk on premature infants and low-birth-weight infants with a birth weight of less than 1,500 g: A literature review2018

    • Author(s)
      井上みゆき, 浅井宏美
    • Journal Title

      Journal of Japanese Society of Child Health Nursing

      Volume: 27 Issue: 0 Pages: 43-48

    • DOI

      10.20625/jschn.27_43

    • NAID

      130006594337

    • ISSN
      1344-9923, 2423-8457
    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 早産児、低出生体重児のNICU退院時の母乳投与に関する検討2018

    • Author(s)
      丸山憲一、小泉亜矢、井上文孝、福田一代、市之宮健二、山崎 優、宮川陽一
    • Journal Title

      日本新生児成育医学会雑誌

      Volume: 31 Pages: 54-61

    • NAID

      40021505630

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] Effect of maternal breast milk intake during NICU admission on development of low birth weight infants at 18 months2020

    • Author(s)
      Miyuki Inoue
    • Organizer
      23rd EAST ASIAN FORUM OF MURSING SCHOLARS
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 群馬県内の母乳栄養の地域差の経時的変化に関する検討2020

    • Author(s)
      丸山憲一
    • Organizer
      第46回日本小児栄養消化器肝臓学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 群馬県内の母乳栄養の児の割合の地域間での違いに関する検討2019

    • Author(s)
      丸山憲一
    • Organizer
      第 122回日本小児科学会学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Influence of Breast Self-care on Breastfeeding for Neonates with a Birth Weight less than 1,500 g Admitted to NICU2019

    • Author(s)
      Inoue Miyuki
    • Organizer
      22nd East Asian Forum of Nursing
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] NICU退院時の母乳投与と極低出生体重児の発達予後との関連:総合周産期母子医療センター2施設における検討2018

    • Author(s)
      丸山憲一
    • Organizer
      第63回日本新生児成育医学会・学術集会
    • Related Report
      2018 Research-status Report
  • [Presentation] 早産児、低出生体重児のNICU退院時の母乳栄養に関連する因子についての検討2017

    • Author(s)
      丸山憲一
    • Organizer
      第14回IBCLCのための母乳育児カンファレンス
    • Place of Presentation
      京都烏丸コンベンションホール
    • Year and Date
      2017-02-25
    • Related Report
      2016 Research-status Report
  • [Presentation] Factors Affecting Development of Very Low Birth Weight Infants at 18Monthsand 3 Years2017

    • Author(s)
      Miyuki Inoue
    • Organizer
      International Nursing Research
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] 出生体重1500g未満の子どもを生んだ母親が実施した母乳分泌促進のセルフケア2017

    • Author(s)
      井上みゆき、一ノ瀬彩加、小林幸美
    • Organizer
      日本新生児看護学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 3 歳発達DQ と予定日体重SD値および母の学歴の関連2017

    • Author(s)
      根本篤、渡邊大輔, 前林祐樹, 長谷部洋平, 小林真美, 齊藤千里, 榊原あい子,井上みゆき,内藤敦
    • Organizer
      第62回日本新生児成育医学会学術集会
    • Related Report
      2017 Research-status Report
  • [Presentation] 早産児または極低出生体重児における母乳の効果に関する文献レビュー2016

    • Author(s)
      井上みゆき
    • Organizer
      第36回日本看護科学学会学術集会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2016-12-10
    • Related Report
      2016 Research-status Report
  • [Presentation] 出生体重1500g以下の早産児における経管栄養(母乳)とNEC発症および1.6歳時の発達2016

    • Author(s)
      井上みゆき
    • Organizer
      第26回日本新生児看護学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2016-12-02
    • Related Report
      2016 Research-status Report
  • [Presentation] 文献レビュー:早産児または低出生体重児におけるドナー母乳の効果2016

    • Author(s)
      浅井宏美・井上みゆき
    • Organizer
      第26回日本新生児看護学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2016-12-02
    • Related Report
      2016 Research-status Report

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Published: 2015-04-16   Modified: 2021-02-19  

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