| Project/Area Number |
15K12701
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied health science
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| Research Institution | Osaka University |
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Principal Investigator |
Yorifuji Shiro 大阪大学, 医学系研究科, 名誉教授 (80191675)
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| Research Collaborator |
ARAKI Toshihiko
ONISHI Mai
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2015: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Keywords | ふたご研究 / 脳磁図 / 運動機能 / 言語機能 / 遺伝 / 環境 / 双子研究 / 動作観察 / 事象関連脱同期 / 遺伝と環境 / ツインスタディ / 高次脳機能 / 言語 / 運動観察 |
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| Outline of Final Research Achievements |
It’s well known that human brain has neuro-plasticity, but there are no data concerning about how human brain changes during long life influenced by gene and environment. Twin study can only solve this question. So we measured movement evoked brain magnetic fields of monozygotic and dizygotic twins during simple finger movement tasks which seemed to be less influenced by environment by magnetoencephalography, and the result of latency differences of movement evoked fields between each twins were significantly small. On the other hand, language function which were more influenced by environment, were measured during verb generation tasks, and the result was that the power values of gamma band event related desynchronization in left frontal area were more significantly related between monozygotic twin pairs than dizygotic and unrelated pairs. We firstly revealed that gene and environment were nearly the same extent influenced on language function in aged human brain.
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