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Development of bifunctional Organocatalysts Utilizing the Property of Ionic Organo-Functional Group

Research Project

Project/Area Number 15K13685
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Synthetic chemistry
Research InstitutionTohoku University

Principal Investigator

TERADA Masahiro  東北大学, 理学研究科, 教授 (50217428)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords有機分子触媒 / 不斉合成 / 触媒 / 水素結合 / 物質変換
Outline of Final Research Achievements

During the past two decades, organocatalysts, the small organic molecule having catalytic activities, have emerged as an efficient catalyst for organic transformations. However catalytic activities and scope of reactions have still limited to establish practical methods using organocatalysts. In order to overcome these conventional issues, we focused our attention on the utilization of ionic organo-functional group in the catalyst design and this key functional group was embedded into the organocatalysts to achieve “unprecedented high catalytic activity”, “high stereoselectivity”, and “wide substrate scope”. The purpose of this study is the development of bifunctional organocatalysts having ionic organo-functional group as a key element for catalyst design to accomplish these high potentials as mentioned above.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (4 results)

All 2017 2015 Other

All Presentation (2 results) (of which Int'l Joint Research: 1 results) Remarks (2 results)

  • [Presentation] 分子内水素結合を介した活性化を設計指針とするカチオン性キラル2017

    • Author(s)
      柄川 冬輝・清水 雅大・菊池 隼・近藤 梓・寺田 眞浩
    • Organizer
      日本化学会 第97春季年会
    • Place of Presentation
      横浜
    • Year and Date
      2017-03-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] Novel active bifunctional organocatalyst having strong base and ammonium moiety as a hydrogen bond donor site2015

    • Author(s)
      Katsunori Dan, Azusa Kondoh, Masahiro Terada
    • Organizer
      Pacifichem2015
    • Place of Presentation
      Hawaii
    • Year and Date
      2015-12-15
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Remarks] 東北大学・大学院理学研究科・化学専攻・反応有機化学研究室ホームページ

    • URL

      http://www.orgreact.sakura.ne.jp/index.html

    • Related Report
      2016 Annual Research Report
  • [Remarks] 東北大学 大学院理学研究科 化学専攻 反応有機化学研究室ホームページ

    • URL

      http://www.orgreact.sakura.ne.jp/index.html

    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2018-03-22  

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