Development of near-infrared fluorescent alloy nanoparticles for detection of cells in deep part of living body based on successive vacuum evaporation method
| Project/Area Number |
15K13724
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Analytical chemistry
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| Research Institution | Wakayama University |
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Principal Investigator |
KIMURA Keiichi 和歌山大学, 学内共同利用施設等, 名誉教授 (50107140)
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| Co-Investigator(Kenkyū-buntansha) |
門 晋平 和歌山大学, システム工学部, 助教 (10423253)
中原 佳夫 和歌山大学, システム工学部, 准教授 (10432600)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 銀超微粒子 / 真空蒸着法 / 保護剤 / オレイル基 / セレン化銀超微粒子 / 近赤外蛍光性 / 原子移動ラジカル重合 / 水分散安定性 / 細胞イメージング剤 / セレン化銀量子ドット / 配位子交換 / オリゴエチレングリコール / 近赤外蛍光 / 透過型電子顕微鏡 / 水分散性 / 真空蒸着 / 銀ナノ粒子 / オレイン酸 / オレイルアミン |
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| Outline of Final Research Achievements |
Effect of protective agents on the preparation of silver nanoparticles by vacuum evaporation on running oil substrate method was investigated. Among five kinds of protective agents bearing a common hydrophobic group (oleyl group), silver nanoparticles, which can be finely re-dispersed in the solvent, were obtained in the high yield in the case of oleic acid. In addition, near-infrared fluorescent silver selenide nanoparticles, which can finely disperse in water, could be obtained by atom transfer radical polymerization of hydrophilic monomers (oligoethyleneglycol methacrylate).
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Report
(3 results)
Research Products
(6 results)
