| Project/Area Number |
15K14217
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Reaction engineering/Process system
|
|---|
| Research Institution | Sojo University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2015-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
|---|
| Keywords | 多孔質材料 / 有機結晶 / シクロデキストリン / 吸着 / 芳香族カルボン酸 / ドラッグキャリア / 両親媒性ナノ孔 / 金属有機構造体 / 多孔質有機結晶 / 結晶化 / 包接 / 新規多孔体 |
|---|
| Outline of Final Research Achievements |
Inner space of cyclodextrin (CD) can include organic compounds due to its hydrophobic nature. Metal-organic framework (CD-MOF) consisting of ganma-CD and KOH was formed by the methanol diffusion method. In addition, CD-MOF is expected to be used as a drug carrier for its biocompatibility. The purpose of this study was to investigate the simultaneous crystallization and inclusion complexation of CD-MOF with ferulic acid. Adsorption behaviors of aromatic carboxylic acids on the CD-MOF were also examined. In the hydrophilic and hydrophobic nanopore of CD-MOF, aromatic carboxylic acids were found to adsorb on the hydrophobic nanopore and be in isolation.
|
