Estimation of three-dimensional blood flow vector by super-harmonic echocardiography

• Project/Area Number: 15K15303
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Cardiovascular medicine
• Research Institution: Tohoku University
• Principal Investigator: SAIJO Yoshifumi 東北大学, 医工学研究科, 教授 (00292277)
• Co-Investigator(Kenkyū-buntansha): 長谷川 英之 富山大学, 大学院理工学研究部(工学), 教授 (00344698)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000); Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 超音波 / 血流ベクトル / 2次元 / 3次元 / 超音波ドプラ法 / スーパーハーモニック

Outline of Final Research Achievements

A broadband sector ultrasound probe with 64 elements was developed and ultrasound was emitted and received by a programmable ultrasound RF signal processor. Two-dimensional blood flow velocity was deduced by measuring the blood flow vectors from two different viewpoints. The algorithm was validated by a mock blood flow model. Two-dimensional blood flow information on parallel planes were input in three-dimensional equation of continuity and an algorithm for three-dimensional blood flow measurement was developed.

Research Products

• [Journal Article] Perspective imaging of flow in arterial model obtained with continuous wave Doppler focusing technique. (2016)
  • Author(s): Nagaoka R, Sasaki K, Zama S, Nagone M, Nagai H, Takeuchi Y, Saijo Y
  • Journal Title: Conf Proc 38th IEEE Eng Med Biol Soc Volume: - Pages: 2315-19
  • DOI: 10.1109/embc.2016.7591193
  • Peer Reviewed
• [Journal Article] Measurement of regional pulse-wave velocity using spatial compound imaging of the common carotid artery in vivo (2015)
  • Author(s): Ryo Nagaoka, Genta Masuno, Kazuto Kobayashi, Shin Yoshizawa, Shin-ichiro Umemura, Yoshifumi Saijo
  • Journal Title: Ultrasonics Volume: 55 Pages: 92-103
  • DOI: 10.1016/j.ultras.2014.07.018
  • Peer Reviewed
• [Journal Article] Intrinsic elastography and its dependence on arterial flow volume. (2015)
  • Author(s): Nagaoka R, Kobayashi K, Yoshizawa S, Umemura S, Saijo Y
  • Journal Title: Conf Proc 37th IEEE Eng Med Biol Soc Volume: 1 Pages: 6301-6312
  • DOI: 10.1109/embc.2015.7319835
  • Peer Reviewed
• [Presentation] Two-dimensional blood flow vector and wall shear stress of carotid artery obtained with dual-angle Doppler method. (2016)
  • Author(s): Akagawa O, Fukazu K, Nagaoka R, Saijo Y
  • Organizer: 2016 IEEE International Ultrasonics Symposium
  • Place of Presentation: Tours, France.
  • Year and Date: 2016-09-18
  • Int'l Joint Research
• [Presentation] 高フレームカラードプラ画像のイメージプロセッシングに関する研究 (2015)
  • Author(s): 赤川紀，長岡亮，深津幸助，西條芳文
  • Organizer: 第18回日本栓子検出と治療学会
  • Place of Presentation: 栃木県総合文化センター（栃木県・宇都宮市）
  • Year and Date: 2015-09-25
• [Presentation] 粒子画像速度計測を用いた頸動脈二分岐モデルにおける速度ベクトル分布推定 (2015)
  • Author(s): 深津幸助，赤川紀，長岡亮，西條芳文
  • Organizer: 第18回日本栓子検出と治療学会
  • Place of Presentation: 栃木県総合文化センター（栃木県・宇都宮市）
  • Year and Date: 2015-09-25
• [Remarks] 西條研究室ホームページ
  • URL: http://www.ecei.tohoku.ac.jp/imaging/index.htm