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VATS lobectomy under HELIOX inhalation

Research Project

Project/Area Number 15K15518
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Respiratory surgery
Research InstitutionWakayama Medical University

Principal Investigator

Kokawa Yozo  和歌山県立医科大学, 医学部, 博士研究員 (30336888)

Co-Investigator(Kenkyū-buntansha) 吉増 達也  和歌山県立医科大学, 医学部, 准教授 (60316099)
Research Collaborator YOSHIMASU TATSUYA  和歌山県立医科大学, 医学部, 准教授 (60316099)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords肺癌 / 胸腔鏡手術 / ヘリウムガス / 胸腔鏡下肺葉切除術 / ヘリオックス
Outline of Final Research Achievements

Heliox is a breathing gas composed of a mixture of helium and oxygen and is used when diving. In order to verify whether Heliox ventilation promotes surgical side pulmonary collapse, a randomized phase II study was performed on lung cancer patients who underwent thoracoscopic surgery. 18 cases were Heliox inhalated ventilation (group H) and 15 cases were normal ventilated group (group C). The visual field was secured (VG) and the degree of collapse of the lung (AG) were evaluated in 5 stages respectively.
There were no significant differences in H group and C group among age, gender, operation type, lesion occupation site, preoperative respiratory function.
There were no significant differences in H group and C group among VG, AG, operation time, bleeding volume, postoperative hospital stay days, drainage period, drain total waste volume, intraoperative SpO2 minimum value, postoperative SpO2 lowest value, postoperative white blood cell maximum value, postoperative CRP maximum value.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (2 results)

All 2017 2016

All Presentation (2 results)

  • [Presentation] Heliox吸入下胸腔鏡下肺葉切除術の臨床試験2017

    • Author(s)
      吉増達也, 川後光正, 平井慶充, 大橋拓矢, 矢田由美, 尾浦正二, 宮坂美和子,西口春香,青石裕香,房本安矢,西村好晴
    • Organizer
      第70回日本胸部外科学会定期学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] HELIOX吸入を用いた胸腔鏡下肺葉切除術の開発2016

    • Author(s)
      吉増達也,尾浦正二,粉川庸三,川後光正,平井慶充,宮坂美和子,矢田由美,本田麻里子,青石裕香,奥あや,西村好晴
    • Organizer
      第69回日本胸部外科学会定期学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2016-09-28
    • Related Report
      2016 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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